• A pedigree is a chart of the genetic history of a family over several generations.
  • Males are represented as squares.
  • Females are represented as circles.
  • Shaded symbols signify that the individual is affected by the condition.
  • Unshaded shapes signify that the individual is unaffected by the condition.
  • A horizontal line between man and woman represents mating and resulting children are shown as offshoots to this line.
  • Generations are labeled with Roman numerals.
  • Individuals are ordered best on age. Oldest to the left, and youngest to the right.

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Autosomal Dominant -

  • If both parents are affected and an offspring is unaffected, the trait must be autosomal dominant (parents are both heterozygous).
  • All affected individuals for autosomal dominant must have at least one affected parent.
  • If both parents are unaffected for autosomal dominant traits, all offspring must be unaffected (homozygous recessive).

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Autosomal Recessive -

  • If both parents are unaffected and an offspring is affected in autosomal recessive, the trait must be recessive (parents are heterozygous carriers).
  • If both parents show a trait in autosomal recessive, all offspring must also exhibit the trait (homozygous recessive).

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X-Linked Recessive -

  • If a female shows a trait in X-linked recessive, so too must all sons as well as her father.
  • An unaffected mother in x-linked recessive genes can have affected sons if she is a carrier (heterozygous).
  • X-linked recessive traits tend to be more common in males.