Infection Control

Terminology

  • Biohazard: Biological hazard; harmful to health.

  • Biosafety: Safe handling of biological substances.

  • Blood-borne pathogen: Infectious microorganisms in blood/body fluids.

  • CDC: Center for Disease Control; investigates and controls diseases.

  • DOT: Department of Transportation.

  • NIOSH: National Institute for Occupational Safety and Health; research and prevention for workplace injuries.

  • OSHA: Occupational Safety and Health Administration; enforces safe working conditions.

Chain of Infection

  • Infection: Occurs when microorganisms invade the body and cause disease.

  • Microorganism: Microscopic organism; includes bacteria, viruses, fungi, and protozoa.

  • Pathogen: Microorganism that causes disease.

  • Nosocomial infections: Acquired in hospitals.

  • Healthcare-associated infections (HAI): Infections from healthcare delivery in all settings.

Components of Chain of Infection

  • Infectious agent: Pathogenic microbe causing infection.

  • Reservoir: Place where microorganisms survive and multiply (e.g., humans, animals, food, water).

  • Exit pathway: How pathogen exits (eyes, nose, mouth, blood).

  • Means of transmission: Includes airborne, contact (direct/indirect), droplet, vector, vehicle.

  • Entry pathway: Ways pathogens enter the body (orifices, mucous membranes, skin breaks).

  • Susceptible host: Individuals with reduced ability to resist infection (newborns, elderly, immunocompromised).

Infection Control Procedures

  • Infection control program: Required to monitor and prevent infections.

  • Employee screening/immunization: Required TB screening, immunizations provided free (HBV, MMR).

  • Hand hygiene: Essential for infection prevention; includes washing and using alcohol-based cleansers.

  • Personal protective equipment (PPE): Protects against exposure to infectious substances; includes gloves, gowns, masks, and goggles.

    • Gloves: Required during high-risk procedures (e.g., phlebotomy).

    • Gowns: Fluid resistant, protects skin.

    • Masks: Protect against droplets; single use.

Infection Control Precautions

  • Universal Precautions: Treat all blood and body fluids as potentially infectious.

  • Body Substance Isolation (BSI): Isolate workers from pathogens.

  • Standard Precautions: Combines elements of UP and BSI.

  • Transmission-based Precautions: Includes airborne, droplet, and contact precautions.

Biosafety

  • Biohazard exposure routes:

    • Parenteral: Exposure other than digestive tract.

    • Ingestion: Hand hygiene neglect leading to contamination.

    • Airborne: Inhalation of aerosols or splashes.

    • Non-intact skin: Exposure through cuts or abrasions.

    • Percutaneous: Needle sticks or similar injuries.

    • Permucosal: Entry through mucous membranes (e.g., eyes).

Blood-Borne Pathogens

  • Blood-borne pathogens: Infectious microorganisms in blood/body fluids (e.g., HBV, HCV, HIV).

  • BBP Standard: OSHA-mandated standard to reduce occupational exposure risk.