6.1 The Molecular Basis for Inheritance
- DNA carries genetic info on how to create proteins the body needs
- 46 chromosomes in a human
- when the body needs a particular protein, a the specifically coded part of the DNA is activated
- the nucleotide sequence is transcribed into a molecule of RNA
- RNA moves to cytosol
- sequence is translated by ribosomes into amino acid chains called polypeptides
- the polypeptides are then turned into functional proteins elsewhere
Heredity and DNA
- Mendel’s pea experiment taught us heredity
- All new cells arise from the division of existing cells and all optimal info is coded int the DNA
- Eukaryotes: stored in nucleus
- Prokaryotes: stored in cytosol
Genes and Chromosomes
- factors that are passed on are derived from genes
- Genes: the coding regions of DNA, which contain the instructions for building the proteins responsible for each inherited trait
- Several versions of gene: alleles
- Histone: a protein molecule around which DNA is wrapped for safeguarding and compression
- Bacterial DNA is stored in loops
- Plasmids: small circular section of DNA found in cytosol of bacteria, replicates independently of chromosomal DNA
- Nucleoid: region that contains looped DNA
The Genome
- complete set of an organism hereditary information
- spread over many chromosomes
- diploid: 2 pairs
- haploid: 1 copy