6.1 The Molecular Basis for Inheritance

  • DNA carries genetic info on how to create proteins the body needs
  • 46 chromosomes in a human
  • when the body needs a particular protein, a the specifically coded part of the DNA is activated
  • the nucleotide sequence is transcribed into a molecule of RNA
  • RNA moves to cytosol
  • sequence is translated by ribosomes into amino acid chains called polypeptides
  • the polypeptides are then turned into functional proteins elsewhere
Heredity and DNA
  • Mendel’s pea experiment taught us heredity
  • All new cells arise from the division of existing cells and all optimal info is coded int the DNA
  • Eukaryotes: stored in nucleus
  • Prokaryotes: stored in cytosol
Genes and Chromosomes
  • factors that are passed on are derived from genes
  • Genes: the coding regions of DNA, which contain the instructions for building the proteins responsible for each inherited trait
  • Several versions of gene: alleles
  • Histone: a protein molecule around which DNA is wrapped for safeguarding and compression
  • Bacterial DNA is stored in loops
  • Plasmids: small circular section of DNA found in cytosol of bacteria, replicates independently of chromosomal DNA
  • Nucleoid: region that contains looped DNA
The Genome
  • complete set of an organism hereditary information
  • spread over many chromosomes
  • diploid: 2 pairs
  • haploid: 1 copy