BIO 120 Lecture Notes

BIO 120 Lecture Notes

Cell Structures

Typical Features of a Cell
  • Organelle: Tiny organ inside a cell responsible for specific functions.

  • Nucleus: Unofficial center of the cell; primary storage location of DNA.

  • Mitochondria: Known as the energy center; organelles that produce ATP through cellular respiration.

  • Cytoskeleton: Provides structural support to the cell; a network of protein filaments and tubules.

  • Centrioles: Essential for cell division; involved in organizing microtubules.

  • Endoplasmic Reticulum (ER): Involved in lipid and protein synthesis.

    • Smooth ER: Lacks ribosomes; involved in lipid and steroid synthesis.

    • Rough ER: Contains ribosomes; site of protein synthesis.

  • Lysosomes: Contain digestive enzymes that break down macromolecules; involved in waste processing.

  • Golgi Apparatus: Modifies, sorts, and packages proteins and lipids; often referred to as the “FedEx” of the cell.

  • Peroxisomes: Organelles that break down specific molecules, including fatty acids and amino acids.

Differences Between Plant and Animal Cells

Similarities
  • Both have mitochondria and a cell membrane.

Differences
  • Animal Cells:

    • Have lysosomes and centrioles.

    • Lack a cell wall.

  • Plant Cells:

    • Have a cell wall, which provides structure and protection.

    • Contain a central vacuole, that stores water and maintains turgor pressure.

    • Possess chloroplasts for photosynthesis.

The Endomembrane System

  • Defined as a specific set of organelles surrounded by membranes.

  • Organelles within this system have specific functions and work together continuously, ensuring efficient cellular processes.

    • Vesicles: Transport materials between organelles; are described as vehicles.

    • Budding: Process by which vesicles are formed by the membrane of an organelle.

    • Merging: Process by which vesicles fuse with the membranes of organelles or the plasma membrane.

Exocytosis and Endocytosis

Exocytosis
  • Defined as the process of exiting molecules from a cell; involves vesicles moving toward the plasma membrane.

Endocytosis
  • Defined as the process of entering molecules into the cell; vesicles fuse with the membrane to facilitate transport.

Functioning of the Endomembrane System

  • Vesicles play a crucial role by fusing with the membranes of organelles or the plasma membrane to transport materials.

  • Transfer of genetic material (DNA, RNA) occurs through nuclear pores to the Endoplasmic Reticulum, where ribosomes synthesize proteins.

Endoplasmic Reticulum (ER)
  • Composed of many membranes called Cisternae.

    • Smooth ER: Engaged in the synthesis of lipids and steroids, no ribosomes present.

    • Rough ER: Has ribosomes attached that synthesize proteins.

    • Hepatic Cells: Involved in breaking down toxins and contain extensive networks of smooth and rough ER.

Golgi Apparatus
  • Functions to modify, package, and transport lipids and proteins; analogous to a shipping company.

  • Modification Methods:

    • Glycosylation: The addition of carbohydrates to proteins; yields glycoproteins which serve protective functions.

    • Glycolipids are also synthesized here.

Lysosomes
  • Described as flexible, movable stomachs in cells that digest waste materials.

  • Maintain a constant internal pH (around 5) optimal for enzyme function.

    • Contain transport proteins (proton pumps) that help maintain the acidic environment inside lysosomes.

  • Example: Tay-Sachs Disease results from lysosomes failing to break down waste effectively.

Vacuoles
  • Large storage structures found within cells.

    • Create osmotic pressure in plant cells, particularly through the central vacuole for water storage.

    • Contractile Vacuole: Present in protists, such as Paramecium, to pump excess water out of the cell.

  • Phagocytosis: The process of engulfing and digesting food particles by the cell.

  • Pinocytosis: The process of ingesting extracellular fluid; it’s often referred to as “cell drinking.”

Organelles Not Included in the Endomembrane System

  • Mitochondria: The powerhouse of the cell, involved in energy production through aerobic respiration.

  • Chloroplasts: Involved in photosynthesis; found in plant cells.

  • Both mitochondria and chloroplasts are thought to have originated from ancient engulfed prokaryotic cells (Endosymbiotic Theory).

Interconnectedness of Cellular Components
  • The cell functions as an integrated unit where no single component operates in isolation.

  • Continuous coordination among organelles is essential for the survival of cells and the overall organism.