Module 1: Reinforce and Recall

Module Practice Guide

Summary Statements‬

‭ 1) Anatomy and physiology are complementary fields of study. This is exemplified by the‬

‭ principle of complementarity wherein a structure’s shape (anatomy) determines its‬

‭ function (physiology).‬

‭ 2) Anatomy is the study of the structure of the body. While gross anatomy focuses on‬

‭ visible structures, microscopic anatomy uses a microscope to study bodily structures.‬

‭ 3) The basic levels of organization in order are as follows: 1) chemical level → 2)‬

‭ cellular level → 3) tissue level → 4) organ level → 5) organ system level → 6) organism‬

‭ level.‬

‭ 4) Homeostasis, which involves maintaining a relatively stable internal environment, is‬

‭ controlled by the nervous and endocrine systems. Homeostatic control mechanisms‬

‭ have 3 components: the receptor (detects change), the control center (determines‬

‭ balance state), and the effector (enables response). Each body system plays a role in‬

‭ maintaining homeostasis.‬

‭ 5) In homeostasis, negative feedback systems are most common and involve increased‬

‭ production of a product resulting in a decrease of the initial stimulus (e.g.,‬

‭ thermoregulation). Positive feedback systems, or cascades, involve increasing the level‬

‭ of the initial stimulus (e.g., blood clotting cascade).‬

‭ 6) Cells, the basic units of life, are necessary for maintenance of tissues, producing‬

‭ molecules and proteins, and energy transfer. Eukaryotic cells, which are defined as‬

‭ having a nucleus (most prominent organelle) and membrane-bound organelles, are the‬

‭ building blocks of the human body. These cells also contain a cytoskeleton composed of‬

‭ microtubules and microfilaments.‬

‭ 7) Organelles serve to carry out the functions of the cell. Several important organelles‬

‭ include the following: nucleus (control center of cell), ribosomes (protein assembly),‬

‭ endoplasmic reticulum (protein modification), Golgi complex (packaging of lipids and‬

‭ proteins), lysosomes (digestive enzymes), proteasomes (protein disassembly), and‬

‭ mitochondria (energy production).‬

‭ 8) Smaller cells have a greater surface area-to-volume ratio, which allows metabolic‬

‭ processes to occur faster. Larger cells, on the other hand, have a small surface‬

‭ area-to-volume ratio, slowing its metabolic rate.‬

‭ 9) The plasma membrane of cells is an asymmetric, dynamic barrier that is composed‬

‭ of proteins and a bilayer of amphipathic phospholipids, which contain outwardly facing‬

‭ hydrophilic (polar, “water-loving”) heads and inwardly facing hydrophobic (non-polar,‬

‭ “water-hating”) tails.‬

‭ 10) The plasma membrane exhibits selective permeability, meaning only certain‬‭‬

‭ materials may cross the barrier. Generally, nutrients move into the cell and wasters‬

‭ move out of the cell. The 3 methods that particles cross a selectively permeable‬

‭ membrane are diffusion (movement of small molecules from high concentration → low‬

‭ concentration), active transport (particle movement against the concentration gradient‬

‭ that requires energy), and vesicular transport (exocytosis, endocytosis, and‬

‭ phagocytosis).‬

‭ 11) Anabolism, which involves synthesis of structures and require energy, and‬

‭ catabolism, which involves breakdown of structures and release of energy, are types of‬

‭ metabolism. Metabolic reactions allow the body to function.‬

‭ 12) Energy, or the ability to do work, exists in several forms in the human body. Potential‬

‭ energy is stored energy, whereas kinetic energy is the energy of motion. Chemical‬

‭ energy is the energy that is stored in chemical bonds, and electrical energy is produced‬

‭ from charged particles moving. Electromagnetic, or radiant energy travels in‬

‭ waves/light. The cell’s main source of energy is ATP, which is produced typically using‬

‭ aerobic pathways, such as cellular respiration.‬

‭ 13) Decomposition reactions (e.g., hydrolysis, food digestion), which break molecules‬

‭ into smaller components, and synthesis reactions (e.g. dehydration), which combine‬

‭ smaller molecules to make larger molecules, are chemical reactions that are typical in‬

‭ the body that allow rearrangement of the atomic structure of molecules.‬

‭ Suggestions for Study Strategies‬

‭ 1) Explain the differences between anatomy and physiology and how they complement‬

‭ each other.‬

‭ 2) List the order of the basic levels of organization of the human body.‬

‭ 3) Write out the basic components of the general homeostatic balance mechanism and‬

‭ their roles.‬

‭ 4) List the roles of the various organ systems in homeostasis.‬

‭ 5) Be able to identify the major organelles of eukaryotic cells and their functions.‬

‭ 6) Explain the relationship between cell size and metabolic rate.‬

‭ 7) Explain the structure and function of the cell membrane. Label the parts of the cell‬

‭ membrane on a diagram. What does it mean when we say that the membrane is‬

‭ selectively permeable?‬

‭ 8) Be able to describe each of the 3 methods by which particles cross the cell‬

‭ membrane.‬

‭ 9) Explain the types of metabolism and chemical reactions that the body uses and the‬

‭ types of energy present in the body.‬

‭ 10) Describe the roles of the major elements and molecules essential for life.‬

Laboratory Practice Guide

Summary Statements‬

‭ 1) The anatomical position is a standard reference point in anatomy where the body is‬

‭ upright, facing forward, with arms at the sides and palms facing forward.‬

‭ 2) Surface Anatomy, Directionality, and Planes: Anatomical vocabulary includes terms‬

‭ for surface landmarks, directional terms, and body planes, which help in accurately‬

‭ describing the locations and movements of body parts in relation to each other. This‬

‭ vocabulary is extensive and is given in the lab manual.‬

‭ 3) Body Cavities and Membrane Linings: The body is divided into cavities or spaces,‬

‭ which have anatomical borders. These cavities are lined by serous membranes, which‬

‭ help reduce friction by secreting fluid as organs move.‬

‭ 4) Osmosis is the movement of water across a semipermeable membrane based on an‬

‭ osmotic gradient created by the solute concentration on either side of the membrane.‬

‭ Water moves from areas of low solute concentration (hypotonic) to high solute‬

‭ concentration (hypertonic), affecting cellular volume and function.‬

‭ Study Tips‬

‭ 1) To memorize surface landmarks, label images, use Post-It notes or tape to label‬

‭ yourself or someone else, or even use a dry erase marker and label yourself in a mirror.‬

‭ 2) To memorize and practice using directional terms, make note cards with 12 or so‬

‭ surface landmarks on them. Shuffle these and then draw two cards and compare them‬

‭ using the directionality terms.‬

‭ 3) Make a concept map to show the branching and division of body cavities. List the‬

‭ type of membrane that would be found lining the wall and organs with the cavity.‬

‭ 4) Draw the 4 and 9 region grids and practice labeling them with their names for the‬

‭ regions and abdominopelvic quadrants.‬

Label Practice