Key Terms

Module 7.1

  • Aerobic: Referring to processes that require oxygen.

  • Anaerobic: Relating to processes that do not require oxygen.

  • Antagonistic: Pertaining to muscles that work against each other to produce movement.

  • Muscles: Tissues in the body that can contract to produce movement.

  • Ballistic: A type of movement that is quick and powerful, often involving a fast release of energy.

  • Movement: The act or process of changing position or location.

  • Cardiac muscles: Muscles that make up the heart, responsible for pumping blood.

  • Central pattern generators: Network of neurons that manage rhythmic movements, such as walking.

  • Extensor: Muscle that extends or straightens a limb.

  • Golgi tendon organs: Sensory receptors that detect tension in muscles.

  • Flexor: Muscle that bends or decreases the angle between body parts.

  • Fast-twitch fibers: Muscle fibers that contract quickly and are used for short bursts of speed.

  • Motor program: A set of commands sent from the brain to execute a movement.

  • Muscle spindle: A sensory receptor located in muscles that detects changes in muscle length.

  • Neuromuscular junction: The synapse or connection between a motor neuron and a muscle fiber.

  • Proprioceptor: Sensory receptor that receives stimuli from within the body, mainly related to position and movement.

  • Reflexes: Automatic responses to stimuli.

  • Skeletal (striated) muscles: Muscles attached to bones that facilitate movement.

  • Slow-twitch fibers: Muscle fibers that are more fatigue-resistant and used for endurance activities.

  • Smooth muscles: Involuntary muscles found in organs that are not under conscious control.

  • Stretch reflex: An automatic muscular response to being stretched.

Module 7.2

  • antisaccade task: A task that measures the ability to inhibit a reflexive eye movement in response to a stimulus.

  • basal ganglia: A group of nuclei in the brain involved in coordinating movement and cognitive processes.

  • cerebellar nuclei: Clusters of neurons located in the cerebellum that play a key role in the coordination of movement.

  • corticospinal tracts: Neural pathways that transmit signals from the cerebral cortex to the spinal cord, controlling voluntary movements.

  • lateral corticospinal tract: The major pathway for voluntary motor control, primarily responsible for fine motor skills in limbs.

  • medial corticospinal tract: A pathway involved in controlling postural and trunk movements.

  • mirror neurons: Neurons that fire when an individual observes an action performed by another, thought to be involved in understanding intentions and social interactions.

  • parallel fibers: Axons that run parallel to each other in the cerebellum, playing a crucial role in cerebellar processing.

  • posterior parietal cortex: A part of the brain that integrates sensory information and helps in spatial awareness and movement planning.

  • prefrontal cortex: The region of the frontal lobe associated with complex cognitive behavior, decision making, and moderating social behavior.

  • premotor cortex: An area of the brain responsible for planning and coordinating movements before they are executed.

  • primary motor cortex: The section of the brain that directly controls voluntary movements of skeletal muscles.

  • Purkinje cells: GABAergic neurons found in the cerebellum, which act to inhibit and modulate the activity of other neurons within cerebellar circuits.

  • readiness potential: A measure of brain activity that precedes voluntary movement, indicating preparation for action.

  • red nucleus: A structure in the midbrain involved in motor coordination and the control of limb movements.

  • striatum or dorsal striatum: A component of the basal ganglia involved in the regulation of movement and a variety of cognitive functions.

  • supplementary motor cortex: An area of the brain involved in the planning of movements and coordination of complex movements.

Module 7.3

  • huntingtin: A protein that is produced by the HTT gene, mutations in which cause Huntington's disease.

  • Huntington's disease: A genetic disorder characterized by the degeneration of neurons in certain areas of the brain, leading to motor dysfunction, cognitive decline, and psychiatric symptoms.

  • L-dopa: A medication used to treat Parkinson's disease, it is a precursor to dopamine that helps improve motor symptoms by replenishing dopamine levels in the brain.

  • MPP+: A neurotoxin derived from MPTP that selectively damages dopaminergic neurons and is used in research to model Parkinson's disease in animals.

  • MPTP: A synthetic compound that causes Parkinson-like symptoms by inducing the degeneration of dopaminergic neurons in the substantia nigra when metabolized into MPP+.

  • Parkinson's disease: A neurodegenerative disorder that primarily affects movement, causing tremors, rigidity, and bradykinesia due to the loss of dopamine-producing neurons.

  • stem cells: Undifferentiated cells that have the potential to develop into various cell types, including neurons, and are being researched for their potential to treat neurodegenerative diseases like Parkinson's and Huntington's disease.