biomed

ABO system 

A system of four types (A, AB, B, and O) which human blood is classified  into, based on the presence or absence of certain antigens.

adenine 

A component of nucleic acids found in DNA and RNA and in the energy carrying molecule, ATP. Adenine is a purine base.

adenosine tri-phosphate  (ATP)

A compound composed of adenosine and three phosphate groups that  supplies energy for many biochemical cellular processes.

agglutination 

The clumping of particles.

algor mortis 

The change in body temperature after death.

anemia 

A condition in which blood is deficient in red blood cells or in functional  red blood cells; leads to reduced oxygen levels in the body.

antibody 

A protein produced by B cells in the blood; works to impair pathogens.  Also called an immunoglobulin.


antigen 

Anything that stimulates an immune response.

aorta 

The largest artery in the body, the aorta carries oxygenated blood from  the left ventricle of the heart to the rest of the body.

aortic valve 

One of four valves in the heart, the aortic valve separates the left ventricle  and the aorta, and functions to prevent blood from flowing back into the  left ventricle.

artery 

A type of vessel that carries blood from the heart through the body; part  of the circulatory system.

atrioventricular node 

Part of the heart’s conduction system that is responsible for controlling  the impulse delivered by the sinoatrial node (SA); also called the AV  node.

atrium 

An upper chamber of the heart where blood enters. The heart has two  atria: the left atrium connects to the lungs and the right atrium connects  to the veins.

autopsy 

A postmortem evaluation to determine cause of death.

B lymphocyte (B cell) 

A type of lymphocyte (white blood cell) that matures in bone marrow and  produces antibodies.


biomedical science 

A professional field combining biology and medicine with a focus on  healthcare.

biomolecule (macromolecule)

A large molecule, or macromolecule, produced by living organisms.  Examples include: nucleic acids (DNA and RNA), carbohydrates,  proteins, and lipids.

blood plasma 

The pale yellow, liquid portion of blood that consists of water and  dissolved substances, including sugars, lipids, metabolic waste products,  amino acids, hormones, and vitamins.

blood pressure 

The pressure that blood exerts upon the walls of blood vessels, especially  arteries, usually measured with a sphygmomanometer and expressed in  millimeters of mercury.

carbohydrate 

A compound, such as sugar, starch and cellulose, found in foods and  living tissues that can be broken down and used for energy.

cardiology 

The field of study focused on the function and diseases of the heart.

cardiovascular system 

The transport system of the body responsible for carrying oxygen and  nutrients to the body and carrying away carbon dioxide and other wastes;  composed of the heart, blood vessels, and blood.

cell 

The smallest unit of life.


chemical bond 

An attractive force that holds together the atoms, ions, or groups of atoms  in a molecule or compound.

chemical indicator 

A substance that changes color depending on the properties (such as  pH) of the solution being tested.

chemical reaction 

A process where atoms and/or molecules are rearranged to transform  matter.

cholesterol 

A lipid that is an essential component of animal cell membranes and acts  as a precursor molecule for the synthesis of other biologically important  steroids.

chronic traumatic  

encephalopathy (CTE)

A progressive degeneration and/or death of nerve cells caused by  repeated head injuries.

concussion 

An injury to the head that causes the brain to quickly move back and  forth, hitting the inside of the skull.

control group 

The group in an experiment where the independent variable being tested  is not applied. The control group serves as a standard for comparison  against the experimental group where the independent variable is  applied.

coronary artery disease 

The narrowing or blockage of the coronary arteries, usually caused by  atherosclerosis.


coronary bypass 

A surgical bypass procedure to reroute blood around an obstruction in a  coronary artery. The procedure involves grafting one end of a segment of  vein removed from another part of the body onto the aorta and the other  end onto the coronary artery beyond the obstructed area to allow for  increased blood flow.

covalent bond 

A chemical bond in which atoms share electron pairs.

cytosine 

A component of nucleic acids (DNA and RNA); a pyrimidine base.

deoxyribonucleic acid  (DNA)

A type of nucleic acid consisting of nucleotide monomers with a  deoxyribose sugar and the nitrogenous bases adenine (A), cytosine (C),  guanine (G), and thymine (T). DNA is double-stranded and helical and  functions in protein synthesis and as the genome of some viruses. 

dependent variable 

In an experiment, the variable being measured and whose value is  influenced by another variable.

diagnosis 

The process of determining which disease or condition explains a  person’s symptoms and signs.

diastole 

The stage in a heartbeat when the heart is relaxed and the heart  chambers fill with blood.

diastolic pressure 

The pressure in arteries between heartbeats, when the heart is relaxed.

digestive system 

An organ system that breaks down food to extract energy and nutrients  and then evacuates remaining waste.

disaccharide 

A sugar that forms when two monosaccharides join in a dehydration  reaction.


disease 

A disorder of structure or function in an organism that results in specific  signs or symptoms, may affect a specific location in the organism, and is  not a direct result of physical injury.

electrocardiogram (EKG) 

A measurement of heart electrical activity.

electrophoresis 

The separation of charged biological molecules by electrical current in a  gel matrix.

erythrocyte (red blood  cell)

Hemoglobin-rich, red blood cells that transport oxygen through a body.  Erythrocytes give the red color to vertebrate blood and do not have  nuclei.

eukaryotic 

Organisms that have membrane-bound organelles.

experiment 

A research study conducted to understand an observed phenomenon;  determines the effect that one variable has upon another variable.

experimental design 

A process used to carefully plan experiments in order to investigate  scientific questions or problems.


forensic chemistry 

A field of chemistry that tests non-biological samples, such as powders,  pills, and other substances, to identify or quantify them.

forensic science 

The application of scientific knowledge to resolve questions of civil and  criminal law.

gel electrophoresis 

The separation of nucleic acids or proteins on the basis of their size and  electrical charge for analytical purposes.

glucagon 

A hormone secreted by pancreatic endocrine cells that raises blood  glucose levels; an antagonistic hormone to insulin.

glucose 

A monosaccharide, or simple sugar, with the chemical formula C6H12O6;  made primarily by plants.

glucose tolerance test 

A test of the body’s ability to metabolize glucose that involves the  administration of a measured dose of glucose to the fasting stomach and  the determination of blood glucose levels in the blood or urine at intervals  thereafter; used especially to detect diabetes.

guanine 

A component of nucleic acids (DNA and RNA); a purine base.



Health Insurance  

Portability and  

Accountability Act  

(HIPAA)

A set of U.S. national standards that protect an individual’s privacy rights  related to their personal medical information.

heart attack 

An acute episode of heart disease that leads to damage or death of heart  muscle due to insufficient blood supply to the muscle.

heart disease 

An abnormal organic condition of the heart or circulation.

heart rate 

A measure of cardiac activity usually expressed in number of beats per  minute.

helix 

A three-dimensional spiral.

hematocrit 

The proportion, by volume, of blood that is made up of red blood cells.

hemoglobin 

A protein found in red blood cells that transports oxygen.

hemoglobin A1c 

A blood test that measures a patient’s average blood sugar level over two  to three months.

high-density lipoprotein (HDL)

The “good” cholesterol that helps remove the less beneficial forms of  cholesterol from blood.

histology 

The study of the microscopic anatomy of tissues. Also known as  microanatomy.

homeostasis 

The maintenance of stable internal physiological conditions (like body  temperature or the pH of blood), which enables the optimal functioning of  an organism.


hormone 

A signaling molecule produced by glands. A hormone induces a specific  effect on the activity of cells.

hydrophilic 

Having an affinity for water and a tendency to dissolve in, become wet by,  or mix with water.

hydrophobic 

Having an aversion to water and a tendency to coalesce and form  droplets in water.

hyperglycemia 

An excess of sugar in the blood.

hypertension 

An abnormally high blood pressure.

hypoglycemia 

An abnormal decrease of sugar in the blood.

hypothesis 

A statement predicting the anticipated results of an experiment.

independent variable 

In an experiment, the variable that the researcher intentionally changes to  determine its influence on the dependent variable.

inferior vena cava 

The largest vein in the human body, the inferior vena cava returns blood  to the right atrium of the heart from body parts below the diaphragm.

insulin 

A protein hormone secreted by the pancreas; essential for the  metabolism of carbohydrates and the regulation of glucose levels in the  blood.

ionic bond 

A bond between atoms that results from the attraction between  oppositely charged ions.


leukocyte (white blood  cell)

One of the many cells in the blood that lack hemoglobin but have a  nucleus and are active in the immune response. Lymphocytes,  monocytes, neutrophils, eosinophils, and basophils are leucocytes.

lipid 

One of a family of compounds, including fats, phospholipids, and steroids,  that is insoluble in water.

livor mortis 

Pooling of the blood following death that causes a purplish  red discoloration of the skin; also referred to as lividity. 

low-density lipoprotein (LDL)

The “bad” cholesterol that can build up in the arteries and help form  plaques, which can cause coronary artery disease.

macromolecule 

A type of large molecule formed by joining smaller molecules. Proteins,  polysaccharides, lipids, and nucleic acids are macromolecules.

magnetic resonance  imaging (MRI)

A medical imaging technique that uses magnetic fields and radio waves  to take pictures of the soft tissues of the body.

malignant 

A cancerous tumor which will grow and spread to invade other tissues or  parts of the body.

measurable 

1. Able to be measured. 

2. A measurable design criterion provides a precise indicator of a quantifiable characteristic so that a design can be compared to the criterion and deemed acceptable or unacceptable.

medical examiner 

A physician who performs an autopsy when a death might have been  caused accidentally or intentionally. In some jurisdictions, the Medical  Examiner may also serve as the coroner.

medical history 

A record of information about a patient’s past and current health. Includes  information about the patient’s habits, lifestyle, and the health of their  family.


metabolic syndrome 

A group of concurrent diseases (high blood pressure, high blood sugar,  obesity, and high cholesterol) that can result in heart disease, stroke, and  Type 2 Diabetes.

metabolism 

The chemical reaction processes of breaking down molecules for energy  and of using simple building blocks to build up more complex molecules  needed for growth and repair.

metastasis 

The spread of cancerous cells to other tissues or parts of the body.

microbiology 

The study of microorganisms, including archaea, bacteria, protists, fungi,  viruses, and prions.

mitral valve 

A valve in the heart that guards the opening between the left atrium and  the left ventricle; prevents the blood in the ventricle from returning to the  atrium. Also called bicuspid valve.

model 

An accurate representation of an object or phenomenon. Models can be  visual, physical, mathematical, or computational; they are often used in  the development of scientific theories or the engineering of artifacts.

molecule 

A group of atoms held together by chemical bonds.

monomer 

A type of molecules that are the building blocks of polymers.

monosaccharide 

The simplest type of sugar that cannot be broken down into other types  of sugars. Glucose and fructose are monosaccharides.

morgue 

A place where the bodies of dead persons are kept temporarily pending  identification or release for burial or autopsy.


negative control 

In an experiment, the group in which the conditions produce a negative  outcome. Negative control groups help identify outside influences that  were not accounted for when the procedure was created.

negative feedback 

A mechanism of homeostasis in which a change in a physiological  variable triggers a reduction in another variable.

nervous system 

The body system in vertebrates that is made up of the brain and spinal  cord, nerves, ganglia, and parts of the receptor organs. The nervous  system receives and interprets stimuli and transmits impulses to muscles  or glands.

nucleotide 

A building block of DNA that consists of a five-carbon sugar covalently  bonded to a nitrogenous base and a phosphate group.

nutrient 

A substance that the body needs to maintain life and health, such as  proteins, lipids, vitamins, and minerals.

organ 

A collection of tissues in an organism that performs a specific function,  such as the heart, brain, skin, and liver.

organ system 

A group of organs that work together to perform one or more functions.

organelle 

Tiny structures that perform a function in a cell. Functions can include:  producing energy, housing DNA, packaging proteins, and more.

personal protective  

equipment (PPE)

Specialized clothing or equipment that a person wears for protection  against laboratory hazards, such as infectious materials and chemicals.


polymer 

A large molecule consisting of many repeating monomers (chemical units  or molecules) linked together.

polymerase chain  

reaction (PCR)

A laboratory technique for amplifying DNA in-vitro. Uses a thermocycler,  primers, DNA polymerase, and nucleotides.

polysaccharide 

A polymer of monosaccharides (simple sugars) formed by dehydration  synthesis.

positive control 

In an experiment, the group that the researcher expects to have a  positive result, to show that the experimental setup was capable of  producing results.

positive feedback 

A mechanism of homeostasis in which a change in a physiological  variable triggers an increase in another variable.

problem statement 

A clear and concise identification and description of a design problem or  opportunity.

prognosis 

The likely course a disease will take over an individual’s lifetime.

prokaryotic 

Lacking membrane-bound organelles. Unicellular organisms are  prokaryotic.


pulmonary artery 

The large blood vessels that carry deoxygenated blood from the heart to  the lungs.

pulmonary circulation 

Part of the circulatory system in which deoxygenated blood moves from  the right ventricle of the heart to the lungs (through arteries) to become  oxygenated and then returns to the left side of the heart (through veins).

pulmonary valve 

A one-way valve by which blood leaves the heart through arteries. The  valve prevents blood from returning into the right ventricle.

pulmonary vein 

The blood vessels that carry oxygenated blood from the lungs to the left  atrium.

pulse 

The rhythmic expansion and recoil of arteries resulting from heart  contraction.

purine 

An aromatic, heterocyclic organic compound that consists of a pyrimidine  ring fused to an imidazole ring. Adenine and guanine are purines.

pyrimidine 

An aromatic, heterocyclic organic compound. Thymine and cytosine are  pyrimidines.

qualitative 

A description of the qualities of something; color, shape, texture.

quantitative 

A description of the amount of something; how much, how often.

recognition sites 

A sequence of DNA where a restriction enzyme cuts.

respiratory rate 

The number of breaths an organism takes per minute.

respiratory system 

A system of organs that functions in the process of gas exchange  between the body and the environment. The respiratory system consists  of especially the nose, nasal passages, nasopharynx, larynx, trachea,  lungs, bronchi, and alveoli.

restriction digestion 

The process of cutting DNA molecules into smaller pieces using  restriction enzymes.


restriction enzyme 

A degradative enzyme that recognizes specific nucleotide sequences and  cuts DNA at these sequences called restriction sites. Also known as a  restriction endonuclease.

restriction fragment  

length polymorphisms  (RFLPs)

Variations in DNA fragment sizes produced when DNA is cut with  restriction enzymes. The variations in length are due to differences in  each organism’s DNA sequence.

rigor mortis 

The stiffening of joints and muscles after death.

sinoatrial node 

Part of the heart’s conduction system that is responsible for heart rate.  Also called the SA node.


sphygmomanometer 

An instrument for measuring blood pressure, especially arterial blood  pressure.

stroke 

The sudden loss or reduction of blood supply to the brain resulting in  tissue damage, disability, or death.

superior vena cava 

The second largest vein in the human body. The superior vena cava  returns blood to the right atrium of the heart from the upper half of the  body.

symptom 

Any subjective evidence of disease that a patient perceives

system 

A group of organs in a body that work together to perform a specific  function.

systemic circulation 

The series of vessels that bring oxygenated blood from the heart to  tissues and return deoxygenated blood from the tissues back to the heart.

systole 

The stage in a heartbeat when contraction of the heart pushes blood out  of the chambers and into the aorta and pulmonary artery.

systolic pressure 

The pressure generated by the heart’s left ventricle during systole.

T lymphocyte (T cell) 

A type of white blood cell (lymphocyte) produced by the thymus and  involved in the immune response.


thrombocyte (platelet) 

A minute, colorless, anucleate disk-like body of mammalian blood that  assists in blood clotting by adhering to other platelets and damaged  epithelium.

thymine 

A component of the nucleic acid, DNA; a pyrimidine base.

tissue 

An integrated group of cells with a common function and/or structure.

tissue typing 

A process where surface antigens, the HLA, of the tissues of a  prospective donor and recipient are tested to determine compatibility for  transplantation.

trace evidence 

Tiny fragments of physical evidence, such as hairs, fibers from clothing or  carpeting, and pieces of glass.

traumatic brain injury  (TBI)

A brain dysfunction caused by an outside force to the head. 

tricuspid valve 

The valve situated at the opening of the right atrium of the heart into the  right ventricle. The tricuspid valve resembles the mitral valve in structure  but consists of three triangular membranous flaps.


type 1 diabetes 

A form of diabetes that usually develops during childhood or  adolescence. Type 1 is characterized by a severe deficiency of insulin,  leading to high blood glucose levels.

type 2 diabetes 

A form of diabetes that develops especially in adults, most often obese  individuals. Type 2 is characterized by high blood glucose resulting from  impaired insulin use coupled with the body’s inability to compensate with  increased insulin production.

uracil 

A component of the nucleic acid, RNA; a pyrimidine base.

valve 

A body structure that temporarily closes a passage or orifice, or permits  movement of fluid in only one direction.

vein 

A vessel that returns blood—typically deoxygenated—to the heart.

ventricle 

A lower chamber of the heart where blood exits. The heart has two  ventricles: the left ventricle connects to the aorta and the right ventricle  connects to the main pulmonary artery (or pulmonary trunk).

vessel 

A tube—a blood vessel or lymph vessel—in which a body fluid is  transported through the body.

vital signs 

Measurements—specifically pulse rate, temperature, respiration rate, and  blood pressure—that indicate the state of a patient’s essential body  functions.