DIY Pharma (1)
Page 1: Clicker Question
Experience of THE QUIZ?
Responses include:
Confusion about which quiz.
Challenging feelings for Yankees fans.
Frustration from doomscrolling election news.
Ease felt by Dodgers fans.
Need to find a Halloween costume.
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Page 3: DIY Pharma
Questioning the feasibility of manufacturing drugs or designing medical devices at home.
Page 4: Class Exercise
Discuss in groups about DIY experiences.
Questions to consider:
What was your DIY project and motivation?
What defines a project as DIY?
Discuss limits of DIY endeavors.
Would you DIY in healthcare (dentistry, surgery, pharmaceuticals)?
Share any DIY disaster stories.
Page 5: Today's Questions
Exploration of why DIY Pharma exists.
Conditions enabling the DIY Pharma movement.
Page 6: Learning Objectives and Goals
Explain the history of the DIY movement.
Reflect on varying values represented in DIY projects.
Examine the history of self-experimentation.
Discuss implications of technology in DIY.
Analyze the limits of knowledge among DIY practitioners.
Debunk myths around DIY through understanding networks.
Critique the vision of some entrepreneurs involved in DIY.
Connect DIY principles with The Right to Repair movement.
Page 7: Unpacking DIY Pharma
A closer look at the term "DIY Pharma" and its implications.
Page 8: Pharmakons and Pharmaceuticals
Definition of "Pharmakon" from ancient Greek; means cure, poison, or scapegoat.
Plato’s view of writing as a Pharmakon: a remedy and poison metaphorically.
Discussion of technologies (writing, ChatGPT) as modern Pharmakons.
Page 9: Starting Points for the DIY Movement
Overview of the seven key starting points for the DIY movement.
Page 10: Actions Outside Institutional Boundaries
Definition of DIY: activities happening outside professional and institutional limits.
Page 11: Self-Experimentation
Importance of self-experimentation in science; historically significant.
Caution against self-experimentation; liability disclaimer.
Notable role in the historical development of scientific practices.
Page 12: References to Self-Experimentation
Citations of academic studies regarding self-experimentation in medical research.
Page 13: Instances of Self-Experimentation
Statistical representation of self-experimentation instances (1800-1999) across various fields.
Page 14: Changing Trends in Self-Experimentation
Table showing trends in self-experimentation by different fields from 1800-1999.
Page 15: Nobel Prizes and Self-Experimentation
Table outlining Nobel Prize winners who engaged in self-experimentation, including their research areas and causes of death.
Page 16: Mechanics of DIY
Historical context of DIY in relation to mechanical design; necessity of self-created tools pre-WW2.
Parallel development in electronics and DIY culture.
Page 17: Simplicity of Great Inventions
The significance of simplicity in mechanics and invention; natural laws and creativity in DIY.
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Page 19: Radio Shack and Hacking Culture
Overview and reference to Radio Shack’s impact on DIY electronics and hacking culture.
Page 20: Parts and Components for DIY
A list of available components at Radio Shack, aimed at hobbyists and DIYers.
Page 21: Family-Friendly DIY
Post-WW2 promotion of DIY as a family-friendly hobby in suburban areas.
The concept and term "DIY" gained popularity during this time.
Page 22: Google Ngram Viewer
Analysis of the phrase "do it yourself" usage over time using Ngram Viewer.
Page 23: Advertising and DIY Culture
Insights into DIY advertising and cultural references from 1959, emphasizing practical DIY projects.
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Page 26: DIY Healthcare Networks
Historic examples of DIY healthcare networks:
Underground DIY abortion providers (the Janes).
Act Up's advocacy during the AIDS crisis for clinical trials.
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Reference to a documentary on DIY abortion services from the Janes.
Page 28: DIY Doula Zine
Introduction to a zine offering practical, non-medical advice for abortions with a warm voice.
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Page 30: Punk and DIY Politics
Relationship between punk culture and DIY aesthetic; rejection of mass-produced media.
Description of a political stance opposing institutional norms.
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Page 32: Events and DIY Culture
Mention of an event related to DIY culture at UCLA, involving performances and activities.
Page 33: UCLA Punk Collective
Overview of UCLA's Punk Collective; focus on preserving and promoting punk music culture.
Call for participation and research in punk music collecting.
Page 34: The Right to Repair
Discussion of the right to repair for various devices:
Apple products, John Deere equipment, insulin pumps, powered wheelchairs.
Page 35: DIY Innovations in Diabetes Care
Examination of community efforts in developing accessible insulin solutions.
Page 36: John Deere Hacker Access
Mention of a jailbreak for John Deere tractors, showcasing the Right to Repair conflicts.
Page 37: DIYbio and Innovation
Explanation of how DIYbio embodies the convergence of various DIY ideologies and biological experimentation.
Page 38: Costs of DIYbio Equipment
Overview of pricing for DIYbio lab setup, including costs for major lab equipment.
Page 39: Getting Started in DIYbio
Tips for setting up a DIYbio lab on a budget using creative solutions.
Page 40: Community-centered Insulin Production
Description of collaborative efforts to establish accessible insulin production models.
Page 41: Balancing Danger and Disruption in DIYbio
Discussion on the ethical and safety considerations in DIYbio practices.
Page 42: Attraction of DIYbio
Appeals of DIYbio labs, including their non-restrictive intellectual property policies.
Page 43: Circulation of Lab Materials
Examination of the changing perceptions of lab material sharing and intellectual property constraints.
Page 44: Dangers of DIYbio
Considerations of hazards associated with DIYbio practices.
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Page 46: DNA Collection and Ethics
Concerns regarding government collection of genetic data for potential misuse.
Page 47: Hacking DNA
Reference to unethical applications in genetic hacking related to high-profile genetic data.
Page 48: Characteristics of DIY Movements
Explanation of the multifaceted nature of DIY movements: goals, methods, values.
Page 49: Characteristics of DIY Pharma
Characteristics of DIY Pharma projects, including their oppositional nature and reliance on networked expertise.
Page 50: Tour of Exemplary DIY Pharma Projects
Introduction to notable DIY Pharma projects, possibly involving visual media.
Page 51: Scroggins Science-y Scale of Biotech Speculation
Scale regarding the plausibility of various biotech ideas from "WTF!?" to "I’ll take a dozen."
Page 52: Academic DIY Projects
Overview of DIY projects undertaken by academic professionals.
Page 53: Seth Roberts
Presentation of Seth Roberts’ contributions to DIY nutrition and self-experimentation with butter.
Page 54: Roberts' Dietary Experimentation
Overview of Seth Roberts’ column expressing his beliefs on butter consumption impacting cognitive function.
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Page 56: DIY Vaccines Controversy
Examination of risks associated with DIY vaccines and self-experimentation efforts during the pandemic.
Page 57: Zayner and DIY Vaccine Argument
Discussion on Josiah Zayner’s advocacy for personal choice in medical care linked to DIY movements.
Page 58: Artistic Provocations in DIY
Summary of provocative and artistic interpretations of DIY in drug design.
Page 59: Tuur van Balen's Presentation
Description of a performance involving pharmaceutical addition to yogurt, raising ethical questions about DIY biology.
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Page 62: Housewives Making Drugs
Concept of a fictional show addressing hormone synthesis at home, promoting body sovereignty and critique of systems.
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Page 64: Safety Statements
Clarification regarding safety and viability of DIY hormone synthesis at home.
Page 65: Approaches to Drug Costs
Discussion of various DIY initiatives aimed at reducing pharmaceutical costs.
Page 66: 4 Thieves Vinegar Collective
Introduction to the Collective’s project providing affordable alternatives to EpiPens.
Page 67: The Microlab
Overview of the DIY Controlled Lab Reactor (CLR) and its functionalities in drug synthesis.
Page 68: Drug Supply and Equipment
Overview of drug supply and injection equipment available for individuals engaging in DIY processes.
Page 69: Open-source DIY Pharmaceutical Projects
Reflections on the efforts for open-source medicine development by activists.
Page 70: Ascendence Biomedical
Mention of considerations of untested experimental therapies by biohackers.
Page 71: Public Experimentation
Controversial cases of live public experimentation with a DIY herpes treatment.
Page 72: News References
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Page 73: CRISPR Safety Regulations
Discussion surrounding regulations imposed on DIY genetic engineering kits.
Page 74: Open Insulin Foundation Meetings
Notification regarding meetings for new volunteer integration into the Open Insulin project.
Page 75: Open Insulin Initiative
Description of the open and collaborative nature of the Open Insulin Foundation.
Page 76: DIY Insulin Production
Mention of individuals involved in DIY insulin production efforts and their implications.
Page 77: Insulin Accessibility Issue
Insight into the US’s specific challenges with insulin access compared to other regions.
Page 78: Legal Perspectives on DIY Invention
Comparison of patent laws in the US and Europe regarding home experimentation.
Page 79: Regulatory Challenges for Open Insulin
Consideration of regulatory structures needed for successful insulin production.
Page 80: Potential Structures for Insulin Production
Exploration of various models for insulin production within the Open Insulin framework.
Page 81: Scaling Challenges of DIY Projects
Discussion about difficulties faced in scaling DIY projects to broader, practical applications.
Page 82: Appeal of DIY Pharma
Analysis of the reasons behind the sustained interest in DIY Pharma despite challenges.