Helicobacter pylori and its Impact on Gastric Health

Overview of Helicobacter pylori

• Definition: Helicobacter pylori (H. pylori) is a spiral-shaped bacterium that resides in the human stomach.

  • The name 'Helicobacter' comes from the Greek word ‘helix’ meaning spiral, and ‘pylori’, which refers to the pylorus, the lower part of the stomach.

Transmission and Acquisition

• Modes of Transmission:

  • Contaminated food

  • Contaminated water

  • Close contact with an infected individual

Mechanism of Survival

• Survival in Stomach Acid:

  • H. pylori can withstand stomach acidity by producing the enzyme urease.

  • Function of Urease:

    • Urease neutralizes the acidic environment in the stomach, allowing H. pylori to thrive.

Pathogenicity and Effects

• Adhesion and Colonization:

  • The bacterium burrows into the mucus lining that protects the stomach.

  • It attaches to the epithelial cells located underneath the mucus layer.

• Impact on Gastric Health:

  • Disruption of the stomach's defenses leads to:

  • Triggering of inflammation.

  • Development of fissures.

  • Formation of ulcers.

Workshop Information

• Event Details:

  • Type: Three-day workshop

  • Audience: Academic staff and postgraduate students

  • Location: International Institute of Islamic Thought (IIT), West Africa Regional Office

  • Dates: January 26th - 28th, 2026

  • Additional Note: SPARK Camera Settings: 30C, 27mm f/1.6, 1/60s, ISO1006