Anatomical Differences
Similarities and differences among homologous structures help determine how recently species shared a common ancestor
Molecular Comparisons
Chemical comparisons like Amino Acid Sequences
Closely related species have more similar amino acid sequences in proteins, showing shared ancestry.
Weakness: can be affected by mutations
Comparison of small segments of DNA like a single gene
Similar genes across species suggest inherited traits from a common ancestor.
Weakness: only focuses on a small part of the genome, not representing overall relationships
Comparison of genomes.
The more similar the full genomes, the more closely related the species are.
Weakness: Requires advanced technology and lots of data, which isn't always available.