Genetic Drift Notes

Corn Populations and Heritability

  • Two corn populations are discussed.
  • The heritability (h²) is given as 1.0 for both, indicating that all phenotypic variation is due to genetic variation.

Misapplication to Human Races and IQ

  • The discussion references the misapplication of these concepts to human races, specifically IQ scores in the USA.
  • Mentioned are studies of post-WWII children raised in Europe, specifically children of African-American US soldiers, showing no difference in IQ scores.

Chapter 7: Genetic Drift – Isolating the Concept

  • Chapter 7 focuses on genetic drift.
  • To isolate the concept, selection and mutation are ignored.

Definition of Genetic Drift

  • Genetic drift is defined as the random change in allele frequencies within populations.
  • Along with natural selection, it is one of the most important processes affecting allele frequencies.
  • Random events are unpredictable and probabilistic, unlike deterministic events.

Random Change in Allele Frequency

  • Random change in allele frequency is likened to flipping a coin; the probability of an allele frequency increasing or decreasing is equal in any generation.
  • This contrasts with natural selection, where frequency changes are deterministic.

Allele Frequency Graphs

  • Several graphs depict allele frequency (p) over generations.
  • These graphs illustrate the random fluctuations in allele frequencies over time.

Fixation and Loss

  • Genetic drift eventually leads to one allele becoming fixed (frequency = 1) and the other being lost (frequency = 0).
  • Although the process is random, probabilistic predictions can be made.

Probabilistic Nature of Genetic Drift

  • It's impossible to predict what happens in any single generation, but overall trends can be predicted.
  • Eventually, one allele will be fixed, and the other will go extinct.

Start at p = 0.5

  • 20 populations all start at p=0.5p = 0.5. With 9 individuals and 18 gene copies

Probability of Allele Fixation

  • Graphs illustrate allele frequency changes over generations in multiple populations.
  • Probability distributions show the likelihood of allele fixation at different time points (t = 0.1N, 0.2N, 0.5N, N, 2N generations).

Examples of Drift

  • Examples using $$"bw