Neuroscience

chapter 1 (history)

  • biopsychology/neuroscience used interchangeably

  • dated to 1700 BC

    • first recorded writing about brain

    • edwin smith surgical papyrus

      • surgical techniques and brain

    • egyptians didn’t prioritize the brain, greeks did

  • dark ages

    • trepanation

      • first attempt at brain surgery

      • bore hoke in skull to drain pus or let out evil spirits, relieve pressure

  • renaissance

    • brain depicted in art

    • andreas vesalius created anatomy books

  • scientific revolution , 17th/18th century

    • renes descartes (1596-1650)

      • mind and body are separate (dualism)

      • governed by material flesh and the nonphysical soul

      • soul and mind are one, reside in pineal gland (monism)

    • empiricism

      • knowledge through sensory experience of natural world

  • 19th/20th century

    • great advances

      • staining techniques

        • charles darwin

        • wilhelm wundt

        • camillo golgi

        • santiago ramon y cajal

    • phrenology

      • reading bumps on the skull (pseudoscience)

  • importance of biopsychology

    • foundations of other psychology disciplines

    • effective in applied psychology

  • future

    • nanotechnology

      • brain-computer interface

    • whole brain emulation

    • transhumanism

chapter 2 (functional anatomy)

  • nervous system

    • central nervous system

      • brain and spinal cord

    • peripheral nervous system

      • nerves outside of CNS

        • somatic - conscious muscle movement

        • autonomic - not conscious

          • sympathetic - fight or flight

          • parasympathetic - low arousal

    • made up of cells

      • cell membrane keeps structure

        • protein transport

        • extracellular fluid

        • intercellular fluid


    • neuron

      • cell body/soma (entirety of cell)

      • dendrites (branches that protrude from cell body)

        • receive stimulation from other neurons

        • chemical or electrical stimulation

      • axon (only one)

        • contains microtubials that allow neurotransmitter to travel down axon

        • terminal branches

        • terminal butons

        • myelin sheath - covering of axon

      • types of neurons

        • anaxonic

        • bipolar

        • pseudounipolar

        • multipolar

      • supported by glial cells

        • supply nutrients, insulate neurons, cleanup, protect neurons from disease

        • four types

          • astrocytes (CNS)

          • oligodendrocytes (CNS)

          • microglia (CNS)

          • schwann cells (PNS)

    • anatomical directions

      • dorsal - above

      • ventral - below

        • anterior / rostal - toward the face or front

        • posterior - toward the tail or back

        • superior - above

        • inferior - below

        • lateral - to the side

        • medial - to the middle

    • twelve cranial nerves

      • “on old olympic towering tops a fin and german vault, skip, & hop”

        shapiro_1-31669-fig264.png (1000×751)
  • cerebral spinal fluid and ventricles

    • CSF

      • clear liquid

      • removes waste

      • found in/around spinal cord, brain, and in ventricles

        • ventricles are spaces within the brain

        • two lateral ventricles

        • third and fourth ventricle


  • meninges

    • dura mater

      • outer layer rests against skull

    • pia mater

      • membrane following contours of cerebral cortex

    • arachnoid

      • web like membrane between dura and pia

      • contains CSF and blood vessels


  • telecephalon

    • cerebral cortex (neocortex)

      • frontal lobe - decision making, motivation, attention, cognitive resoning

      • parietal lobe - integration of sensory information

      • occipital lobe - visual processing

      • temporal lobe - language, visual, and auditory perception


    • limbic system (emotions, learning, motivation, sexual behavior)

      • amygdala

      • hippocampus

      • cingulate cortex

      • fornix

      • septum

    • basal ganglia (coordinates smooth muscle movement)

      • striatum

      • globus pallidus

      • nucleus accumbens

  • diencephalon

    • thalamus (relay sensory information)

      • lateral geniculate nucleus (visual)

      • medial geniculate nucleus (auditory)

      • ventral posterior nucleus (touch)

    • hypothalamus (hormone regulation)

    • pituitary gland

    • optic chiasm

    • mammillary bodies

  • mesencephalon

    • superior colliculus

    • inferior colliculus

    • periaqueductal grey

    • substantia nigra

    • ventral tegmentum

  • metencephalon

    • pons

    • cerebellum

      • purkinje cells

  • myelencephalon

    • medulla oblongata

    • reticular formation


chapter 3 (neuron communication)

  • ions (charged particles)

  • membrane potential

    • neuron membrane surrounds cell

    • semi-permeable

    • maintains electrical charge between inter and extra cellular fluid

    • membrane potential (The voltage difference between the intracellular fluid and extracellular fluid across the membrane of a neuron.)

    • resting potential (the voltage difference between the intracellular fluid and extracellular fluid across the membrane of a neuron)

  • depolarization

  • repolarization