Biology Playlist Recap Flashcards
Characteristics of Life
- Life is difficult to define, with many exceptions when considering its characteristics.
- The video encourages viewers to think about characteristics of life and what differentiates living from non-living things.
Biological Levels of Organization
- The biological levels of organization start with the cell, the smallest living unit (part of cell theory).
- Cell theory:
- The cell is the smallest living unit in all organisms.
- All living organisms are made up of cells.
- All cells come from pre-existing cells.
- Cells combine to form tissues, tissues form organs, organs form organ systems, and organ systems form an organism.
- An individual organism can be part of a population (same species), a community (different species), an ecosystem (including abiotic factors like rocks and temperature), a biome, and finally the biosphere.
Biomolecules
- Four major macromolecules (biomolecules) are essential for living organisms:
- Carbohydrates
- Lipids
- Proteins
- Nucleic acids
- Their building blocks (monomers) are:
- Monosaccharides (carbohydrates)
- Fatty acid and glycerol (lipids)
- Amino acids (proteins)
- Nucleotides (nucleic acids)
- Monomers are true monomers for carbs, proteins, and nucleic acids.
- Functions of biomolecules are vital for life.
- A popular mnemonic helps remember the major elements in these structures.
Enzymes
- Most enzymes are made of proteins.
- Enzymes have an active site where a substrate binds.
- Enzymes speed up reactions by breaking down or building up substrates.
- Products are formed as a result of enzyme activity.
- Digestive enzymes are specific for breaking down fats, sugars, or proteins.
- Enzymes require a specific temperature and pH range to function correctly; if these conditions are not met, they can denature.
Cells: Prokaryotic vs. Eukaryotic
- Prokaryotic cells lack a nucleus and other membrane-bound organelles.
- Eukaryotic cells have a nucleus and other membrane-bound organelles.
- Mnemonic: pro rhymes with no (no nucleus), and u rhymes with do (do have a nucleus).
- Prokaryotes include bacteria and archaea, while eukaryotes include plants, animals, protists, and fungi.
- Both prokaryotic and eukaryotic cells have common features like DNA, cytoplasm, ribosomes, and a cell membrane.
- Eukaryotes exclusively contain membrane bound organelles like the nucleus, endoplasmic reticulum, Golgi apparatus, and mitochondria.
Cell Membrane (Plasma Membrane)
- The cell membrane is essential for homeostasis as it controls what enters and exits the cell.
- It is composed of phospholipids with polar heads and nonpolar tails.
- Passive transport: Molecules move across the membrane without added energy, following the concentration gradient.
- Simple diffusion
- Facilitated diffusion (through a protein)
- Active transport: Uses ATP to move molecules against the concentration gradient.
- Water moves across the membrane through osmosis, either directly or via aquaporins.
- Osmosis can be viewed as water moving from high to low water concentration or from low to high solute concentration.
- Hypertonic areas have high solute concentration, and water moves towards them.
Organelles: Mitochondria and Chloroplast
- In eukaryotes, mitochondria are involved in cellular respiration, while chloroplasts are involved in photosynthesis.
- Cellular respiration breaks down glucose to produce ATP, which all organisms must make.
- If oxygen is unavailable, some organisms use anaerobic respiration or fermentation.
- Photosynthesis produces glucose using sunlight energy and occurs in chloroplasts in eukaryotic cells.
- Reactants and products are switched between the two processes, but they are not simply the reverse of each other and have different steps.
Nucleus and DNA
- The nucleus of a eukaryotic cell contains DNA.
- DNA, a nucleic acid, carries genetic information found in almost all body cells.
- A nucleotide, the monomer of DNA, consists of a phosphate, deoxyribose, and a nitrogenous base.
- The sequence of bases determines genetic information.
- Mnemonic: "Apples in the tree, cars in the garage" (Adenine pairs with Thymine, Cytosine pairs with Guanine).
- DNA is tightly coiled into chromosomes; humans have 46 chromosomes (23 from each parent).
- DNA consists of two antiparallel strands running five' to three' and three' to five'.
DNA Replication
- DNA replication is necessary for creating new body cells for growth and repair.
- Key player enzymes:
- Helicase: unwinds DNA
- Primase: lays down primers
- DNA polymerase: builds a new strand in the five' to three' direction, requiring primers.
- Ligase: seals Okazaki fragments on the lagging strand.
- Due to the directional building, one strand is a lagging strand with Okazaki fragments.
Cell Cycle
- The cell cycle includes:
- G1 (cell growth)
- S phase (DNA synthesis/replication)
- G2 (further growth and preparation for division)
- M phase (mitosis and cytokinesis)
- G1, S, and G2 are part of interphase (non-dividing phase).
- Checkpoints control whether a cell can continue through the cycle; if requirements aren't met, the cell undergoes apoptosis (self-destruction).
- The cell cycle is controlled by proteins like CDK, cyclin, and p53.
- Cancer cells bypass checkpoints and divide uncontrollably.
Mitosis
- Mitosis is a type of cell division that produces identical body cells for growth and repair.
- Chromosomes (condensed DNA and protein) are easily moved into new daughter cells.
- Mnemonic: PMAT - prophase, metaphase, anaphase, and telophase.
- Cytokinesis splits the cytoplasm, fully dividing the cell.
Meiosis
- Meiosis produces gametes (sperm and egg cells) for sexual reproduction.
- Gametes have half the number of chromosomes as body cells (haploid).
- Body cells are diploid (two sets of chromosomes), while gametes are haploid (one set of chromosomes).
- PMAT occurs twice in meiosis (Meiosis I and Meiosis II), resulting in four haploid cells.
- These cells are genetically different due to independent assortment and crossing over.
- Crossing over occurs during prophase I, where homologous chromosomes exchange information.
Genetics
- In humans, sperm and egg cells have 23 chromosomes each; when combined, the fertilized egg has 46 chromosomes.
- Genes, located on chromosomes, code for specific traits.
- Genes come in different forms called alleles.
- Example: PTC tasting gene has alleles for tasting (T, dominant) and non-tasting (t, recessive).
- Genotypes and Phenotypes:
- TT (homozygous dominant): PTC tasting
- Tt (heterozygous): PTC tasting
- tt (homozygous recessive): non-PTC tasting
- Mendelian inheritance involves the expression of recessive alleles when a dominant allele is not present.
Types of Genetics
- Mendelian genetics include monohybrid and dihybrid crosses, solved using Punnett squares.
- Non-Mendelian inheritance includes:
- Sex-linked traits
- Multiple alleles
- Incomplete dominance
- Codominance
- Incomplete Dominance vs. Codominance: In codominance, both alleles are expressed; in incomplete dominance, the phenotype is a blend of the two traits.
Pedigrees
- Pedigrees track traits of interest (sex-linked or autosomal).
- Females are represented by circles, males by squares; shaded shapes indicate individuals with the trait.
Protein Synthesis
- DNA codes for proteins, which are involved in many traits and functions.
- Two major steps in protein synthesis:
- Transcription: mRNA is made in the nucleus.
- Translation: occurs in the ribosome and produces a polypeptide chain of amino acids.
- Other forms of RNA (rRNA, tRNA) are also involved.
- Codon charts are used to determine which amino acids are produced.
- Proteins often require folding to become functional.
Codons and Mutations
- Codons are three-base sequences on mRNA that specify an amino acid.
- tRNA has an anticodon complementary to the mRNA codon and carries the corresponding amino acid.
- Gene Mutations:
- Substitution
- Deletion
- Insertion
- Insertions and deletions are more likely to cause frameshift mutations.
- Frameshift mutations alter the reading frame, affecting multiple codons.
- Chromosomal Mutations:
- Duplication
- Deletion
- Inversion
- Translocation
- Mutations can be neutral, harmful, or beneficial, but they are random.
Natural Selection
- Natural selection acts on populations where variety exists within a species due to meiosis or mutations.
- Organisms with traits that provide a better fit for their environment (higher fitness) are more likely to survive and reproduce.
- Fitness is determined by reproductive success (number of offspring).
- Over time, the frequency of advantageous traits increases in the population.
Genetic Drift
- Both genetic drift and natural selection are mechanisms of evolution.
- In genetic drift, survival and reproduction are due to random chance, not necessarily biological fitness.
- Examples of genetic drift include the bottleneck effect and founder effect.
Bacteria
- Bacteria are unicellular prokaryotes.
- Some bacteria are autotrophs (make their own food), and others are heterotrophs (consume organic material).
- Bacteria lack a nucleus and membrane-bound organelles but have genetic material, cytoplasm, and ribosomes.
- Bacteria can be helpful or harmful.
- Helpful roles include breaking down food, acting as decomposers, making foods, and fixing nitrogen.
- Harmful bacteria (pathogens) can be treated with antibiotics.
Viruses
- Viruses are not considered living organisms because they are not cells and require a host to reproduce.
- Viruses have genetic material (DNA or RNA) and a protein coat (capsid); some have envelopes.
- Viruses reproduce using the lytic or lysogenic cycle.
- Viral diseases (e.g., common cold, HIV, influenza) do not respond to antibiotics.
Classification of Living Organisms
- Life is organized into three domains: Bacteria, Archaea, and Eukarya.
- Taxonomy levels after domain are: kingdom, phylum, class, order, family, genus, and species.
- Mnemonic: (i.e., "Dear King Philip Came Over For Good Spaghetti")
- Scientific names (binomial nomenclature) are more reliable than common names.
Plants
- Plants are autotrophs that provide a significant amount of Earth's oxygen.
- Structure:
- Nonvascular plants get water by osmosis.
- Vascular plants have xylem (water transport) and phloem (sugar transport).
- Chloroplasts capture light energy.
- Stomata (pores) facilitate gas exchange, controlled by guard cells.
- Reproduction:
- Asexual reproduction
- Sexual reproduction (primarily in flowering plants/angiosperms).
- Angiosperm structures: petals, sepals, anther, filament, stigma, style, ovary.
- Pollination & Fertilization: pollen transfer to stigma, pollen tube formation, sperm fertilizes egg and polar nuclei (double fertilization), ovules become seeds, ovary becomes fruit.
Ecology
Plants are producers in food chains/webs; consumers (heterotrophs) eat other organisms.
Food chains illustrate energy flow:
- producers -> primary consumers -> secondary consumers -> tertiary consumers
Energy pyramid shows energy transfer between trophic levels (approximately 10% energy transfer).
Example Energy flow pyramid with 10,000 kcal at the base:
Energy is lost as heat or undigested material.
Food webs are complex networks of interacting food chains.
Biodiversity contributes to the sustainability of a community.
Ecological Succession
- Ecological succession is the gradual change in an ecological community over time.
- Primary succession: Occurs in new areas without soil like cooled lava flows.
- Pioneer species (lichen, moss) colonize first, breaking down rock and forming soil.
- Small vascular plants, shrubs, and trees follow.
- Secondary succession: Occurs in areas with existing soil after an ecological disturbance (e.g., forest fire).
- Small plants can quickly colonize the area.
Nutrient Cycles
- Carbon cycle: Carbon is found in biomolecules, the ocean, rocks, fossil fuels, living organisms, and the atmosphere (as carbon dioxide).
- Photosynthetic organisms take in carbon dioxide.
- Cellular respiration releases carbon dioxide.
- Decomposition releases carbon stored in sediments.
- Burning fossil fuels releases carbon dioxide.
- Nitrogen cycle: Nitrogen is important in building proteins and nucleic acids.
- Nitrogen-fixing bacteria convert nitrogen into ammonia and ammonium.
- Nitrifying bacteria convert ammonium to nitrates and nitrites.
- Plants assimilate nitrates and nitrites.
- Decomposers return ammonia and ammonium to the soil (ammonification).
- Denitrifying bacteria convert nitrates and nitrites back into nitrogen gas.
Ecological Relationships
- Predation: One organism (predator) eats another (prey).
- Competition: Organisms compete for resources.
- Symbiotic Relationships:
- Commensalism: One organism benefits, the other is neutral.
- Parasitism: One organism benefits (parasite), the other is harmed (host).
- Mutualism: Both organisms benefit.
Human Body Systems
- 11 Body Systems:
- Circulatory
- Digestive
- Endocrine
- Excretory
- Immune/Lymphatic
- Integumentary
- Muscular
- Nervous
- Reproductive
- Respiratory
- Skeletal
- Systems don't work in isolation but work together.