Diagnostic Radiology Physics – Lecture 1 Notes

Introduction to Diagnostic Radiology Physics

  • Course code: ZMT 234/4 – Physics of Diagnostic Radiology

    • Lecturer: Dr. Nurul Hashikin Ab. Aziz

    • Institution: School of Physics, Universiti Sains Malaysia

    • Contact: hashikin@usm.my

  • Session focus: “Introduction to Diagnostic Radiology Physics”

Definition & Scope of Diagnostic Radiology

  • Diagnostic radiology = field of medicine utilising X-rays to:

    • Detect & diagnose diseases / injuries.

    • Manage patient care.

    • Guide various medical treatments.

  • Reference definition: International Atomic Energy Agency (IAEA) link – https://www.iaea.org/resources/rpop/health-professionals/radiology
    (underscores clinical & safety dimensions).

Historical Perspective

  • Wilhelm Conrad Röntgen (inventor of X-rays, 1895).

    • Left slide imagery: portrait of Röntgen.

    • Right slide imagery: first radiograph – his wife’s hand “Hand mit Ringen” (hand with rings).

    • Demonstrated medical potential immediately after discovery.

Electromagnetic (EM) Spectrum – Position of X-rays

  • Wavelength (λ) span presented (approximate):
    100\,\text{m} \;\to\; 0.0001\,\text{nm}

  • Regions & everyday examples:

    • Radio waves – FM/TV, Radar (\sim100\,\text{m} to 1\,\text{m}).

    • Microwaves / IR – TV remote, light bulb.

    • Visible spectrum – sunlight (labelled “Building size” “Atom size” scale overlay).

    • Ultraviolet.

    • X-raysX-ray machine.

    • Gamma rays – highest photon energy.

  • Notable reminder slide: “Where are α and β radiations?”

    • Alpha & beta are particulate, thus not located on EM spectrum.

Radiation Classification

  • Two broad categories:

    1. Particulate Radiation

    • α (\alpha^{++}), β⁺, β⁻, electrons (e^-), protons (p^+), neutrons (n).

    • Directly ionizing (charged particles deposit energy continuously).

    1. Electromagnetic Radiation

    • Radio, microwave, IR, visible, UV, X-rays, γ-rays.

    • Indirectly ionizing photons; energy imparted via liberated secondary electrons.

  • Ionizing vs Non-ionizing EM:

    • Non-ionizing: radio → lower-energy UV.

    • Ionizing: higher-energy UV, X-rays, γ-rays.

  • Ion-pair concept visualised:

    • Photon (h\nu) interacts → ejects electron → ion pair formation.

    • Electron = directly ionizing; photon = indirectly ionizing.

Roles of a Medical Physicist in Diagnostic Radiology (prompt posed)

  • Although explicit bullet list not given, implied duties include:

    • Equipment specification, acceptance & commissioning.

    • Quality control & assurance.

    • Patient & staff radiation safety.

    • Optimisation of image quality vs dose.

    • Teaching & research on emerging technologies.

Course Administrative Information

Course Outline (13 Topics)

  1. X-ray tube & generator.

  2. X-ray spectrum.

  3. X-ray interaction in human body.

  4. Scattered radiation.

  5. Film-screen radiography.

  6. Fluoroscopy.

  7. Tomography.

  8. Mammography.

  9. Digital radiography.

  10. Quality control & testing of radiographic X-ray machine.

  11. Radiographic quality (contrast, resolution, MTF).

  12. Radiation hazards associated with diagnostic radiology.

  13. Current developments in diagnostic radiology.

Course Structure & Weightage

  • Coursework 50 %

    • Tests: 2 \times 7.5\% = 15\%

    • Assignments (4): 25\%

    • Quizzes: 10\%

  • Final Examination: 50\%
    ————————
    Total: 100\%

  • “END of class briefing…” indicates administrative discussion concluded.

Fundamentals of X-ray Production

  • Requires high-speed electrons suddenly decelerated in a target (X-ray tube).

  • Two dominant emission processes: Characteristic & Bremsstrahlung.

Characteristic X-rays

  • Occur when incident electron energy Ee is greater than binding energy of an inner-shell electron Eb.
    Ee > Eb \;\Rightarrow\; \text{eject inner electron}

  • Electron vacancy filled by outer-shell electron → discrete photon emitted:
    E{X\text{-ray}} = E{\text{outer}} - E_{\text{inner}}

  • Energy depends on “gap” between shells; example range:
    E_{K\beta} \approx 10{,}000\,\text{eV} - 100\,\text{eV} (material specific).

  • Spectrum lines labelled: Kα, Kβ, …

    • Idealised intensity chart showed sharp spikes at those energies.

Bremsstrahlung (Braking) X-rays

  • Produced when incident electron is decelerated in the Coulomb field of nucleus.

  • Photon energy distribution is continuous from 0 to the maximum electron kinetic energy.

  • Probability ↑ with higher atomic number Z (denser nuclear charge enhances deceleration).

    • Slide examples: 40\,\text{keV}, 60\,\text{keV}, 100\,\text{keV} electron energies.

  • Photon energy magnitude depends on:

    • Deflection angle of electron.

    • Incident electron energy.

    • Distance of closest approach to nucleus.

Composite X-ray Spectrum (Tube Output)

  • Superposition of:

    • Continuous Bremsstrahlung curve (broad).

    • Discrete characteristic spikes (narrow).

  • Graph axis: relative intensity vs photon energy (0 → 150\,\text{keV}).

    • Endpoint energy equals accelerating voltage (kVp).

    • Peak positions of characteristic lines remain fixed for a given target material.

Ethical, Practical & Real-World Implications (highlighted implicitly)

  • Use of ionizing radiation mandates adherence to radiation protection principles:

    • Justification, Optimisation (ALARA), Dose Limitation.

  • Historical example (Röntgen) shows rapid clinical adoption—but emphasises need for ongoing safety oversight (medical physicist role).

  • Course topics on radiation hazards & quality control reinforce safety culture.

Teasers for Future Lectures

  • Slides hinted at advanced imaging (fluoroscopy, tomography, mammography, digital).

  • Mentions of Soteria.AI, OMEGA, Cytom 16, Nosot could refer to AI or vendor systems—suggesting upcoming discussions on current developments & machine learning in radiology.

Introduction to Diagnostic Radiology Physics - Course code: ZMT 234/4 – Physics of Diagnostic Radiology - Lecturer: Dr. Nurul Hashikin Ab. Aziz - Institution: School of Physics, Universiti Sains Malaysia - Contact: hashikin@usm.my - Session focus: “Introduction to Diagnostic Radiology Physics” ## Definition & Scope of Diagnostic Radiology - Diagnostic radiology = field of medicine utilising X-rays to: - Detect & diagnose diseases / injuries. - Manage patient care. - Guide various medical treatments. - Reference definition: International Atomic Energy Agency (IAEA) link – https://www.iaea.org/resources/rpop/health-professionals/radiology

(underscores clinical & safety dimensions). ## Historical Perspective - Wilhelm Conrad Röntgen (inventor of X-rays, 1895). - Left slide imagery: portrait of Röntgen. - Right slide imagery: first radiograph – his wife’s hand “Hand mit Ringen” (hand with rings). - Demonstrated medical potential immediately after discovery. ## Electromagnetic (EM) Spectrum – Position of X-rays - Wavelength (λ) span presented (approximate):

100\,\text{m} \;\to\; 0.0001\,\text{nm} - Regions & everyday examples: - Radio waves – FM/TV, Radar (\sim100\,\text{m} to 1\,\text{m}). - Microwaves / IR – TV remote, light bulb. - Visible spectrum – sunlight (labelled “Building size” “Atom size” scale overlay). - Ultraviolet. - X-raysX-ray machine. - Gamma rays – highest photon energy. - Notable reminder slide: “Where are α and β radiations?” - Alpha & beta are particulate, thus not located on EM spectrum. ## Radiation Classification - Two broad categories:1. Particulate Radiation - α (\alpha^{++}), β⁺, β⁻, electrons (e^-), protons (p^+), neutrons (n). - Directly ionizing (charged particles deposit energy continuously). 1. Electromagnetic Radiation - Radio, microwave, IR, visible, UV, X-rays, γ-rays. - Indirectly ionizing photons; energy imparted via liberated secondary electrons. - Ionizing vs Non-ionizing EM: - Non-ionizing: radio → lower-energy UV. - Ionizing: higher-energy UV, X-rays, γ-rays. - Ion-pair concept visualised: - Photon (h\nu) interacts → ejects electron → ion pair formation. - Electron = directly ionizing; photon = indirectly ionizing. ## Roles of a Medical Physicist in Diagnostic Radiology (prompt posed) - Although explicit bullet list not given, implied duties include: - Equipment specification, acceptance & commissioning. - Quality control & assurance. - Patient & staff radiation safety. - Optimisation of image quality vs dose. - Teaching & research on emerging technologies. ## Course Administrative Information ### Course Outline (13 Topics) 1. X-ray tube & generator. 2. X-ray spectrum. 3. X-ray interaction in human body. 4. Scattered radiation. 5. Film-screen radiography. 6. Fluoroscopy. 7. Tomography. 8. Mammography. 9. Digital radiography. 10. Quality control & testing of radiographic X-ray machine. 11. Radiographic quality (contrast, resolution, MTF). 12. Radiation hazards associated with diagnostic radiology. 13. Current developments in diagnostic radiology. ### Course Structure & Weightage - Coursework 50 % - Tests: 2 \times 7.5\% = 15\% - Assignments (4): 25\% - Quizzes: 10\% - Final Examination: 50\%

————————

Total: 100\% - “END of class briefing…” indicates administrative discussion concluded. ## Fundamentals of X-ray Production - Requires high-speed electrons suddenly decelerated in a target (X-ray tube). - Two dominant emission processes: Characteristic & Bremsstrahlung. ### Characteristic X-rays - Occur when incident electron energy Ee is greater than binding energy of an inner-shell electron Eb.

Ee > Eb \;\Rightarrow\; \text{eject inner electron} - Electron vacancy filled by outer-shell electron → discrete photon emitted:

E{\text{X-ray}} = E{\text{outer}} - E_{\text{inner}} - Energy depends on “gap” between shells; example range:

E_{K\beta} \approx 10{,}000\,\text{eV} - 100\,\text{eV} (material specific). - Spectrum lines labelled: Kα, Kβ, … - Idealised intensity chart showed sharp spikes at those energies. ### Bremsstrahlung (Braking) X-rays - Produced when incident electron is decelerated in the Coulomb field of nucleus. - Photon energy distribution is continuous from 0 to the maximum electron kinetic energy. - Probability ↑ with higher atomic number Z (denser nuclear charge enhances deceleration). - Slide examples: 40\,\text{keV}, 60\,\text{keV}, 100\,\text{keV} electron energies. - Photon energy magnitude depends on: - Deflection angle of electron. - Incident electron energy. - Distance of closest approach to nucleus. ## Composite X-ray Spectrum (Tube Output) - Superposition of: - Continuous Bremsstrahlung curve (broad). - Discrete characteristic spikes (narrow). - Graph axis: relative intensity vs photon energy (0 → 150\,\text{keV}). - Endpoint energy equals accelerating voltage (kVp). - Peak positions of characteristic lines remain fixed for a given target material. ## Ethical, Practical & Real-World Implications (highlighted implicitly) - Use of ionizing radiation mandates adherence to radiation protection principles: - Justification, Optimisation (ALARA), Dose Limitation. - Historical example (Röntgen) shows rapid clinical adoption—but emphasises need for ongoing safety oversight (medical physicist role). - Course topics on radiation hazards & quality control reinforce safety culture. ## Teasers for Future Lectures - Slides hinted at advanced imaging (fluoroscopy, tomography, mammography, digital). - Mentions of Soteria.AI, OMEGA, Cytom 16, Nosot could refer to AI or vendor systems—suggesting upcoming discussions on current developments & machine learning in radiology.

Introduction to Diagnostic Radiology Physics - Course code: ZMT 234/4 – Physics of Diagnostic Radiology - Lecturer: Dr. Nurul Hashikin Ab. Aziz - Institution: School of Physics, Universiti Sains Malaysia - Contact: hashikin@usm.my - Session focus: “Introduction to Diagnostic Radiology Physics” ## Definition & Scope of Diagnostic Radiology - Diagnostic radiology = field of medicine utilising X-rays to: - Detect & diagnose diseases / injuries. - Manage patient care. - Guide various medical treatments. - Reference definition: International Atomic Energy Agency (IAEA) link – https://www.iaea.org/resources/rpop/health-professionals/radiology

(underscores clinical & safety dimensions). ## Historical Perspective - Wilhelm Conrad Röntgen (inventor of X-rays, 1895). - Left slide imagery: portrait of Röntgen. - Right slide imagery: first radiograph – his wife’s hand “Hand mit Ringen” (hand with rings). - Demonstrated medical potential immediately after discovery. ## Electromagnetic (EM) Spectrum – Position of X-rays - Wavelength (λ) span presented (approximate):

100\,\text{m} \;\to\; 0.0001\,\text{nm} - Regions & everyday examples: - Radio waves – FM/TV, Radar (\sim100\,\text{m} to 1\,\text{m}). - Microwaves / IR – TV remote, light bulb. - Visible spectrum – sunlight (labelled “Building size” “Atom size” scale overlay). - Ultraviolet. - X-raysX-ray machine. - Gamma rays – highest photon energy. - Notable reminder slide: “Where are α and β radiations?” - Alpha & beta are particulate, thus not located on EM spectrum. ## Radiation Classification - Two broad categories:1. Particulate Radiation - α (\alpha^{++}), β⁺, β⁻, electrons (e^-), protons (p^+), neutrons (n). - Directly ionizing (charged particles deposit energy continuously). 1. Electromagnetic Radiation - Radio, microwave, IR, visible, UV, X-rays, γ-rays. - Indirectly ionizing photons; energy imparted via liberated secondary electrons. - Ionizing vs Non-ionizing EM: - Non-ionizing: radio → lower-energy UV. - Ionizing: higher-energy UV, X-rays, γ-rays. - Ion-pair concept visualised: - Photon (h\nu) interacts → ejects electron → ion pair formation. - Electron = directly ionizing; photon = indirectly ionizing. ## Roles of a Medical Physicist in Diagnostic Radiology (prompt posed) - Although explicit bullet list not given, implied duties include: - Equipment specification, acceptance & commissioning. - Quality control & assurance. - Patient & staff radiation safety. - Optimisation of image quality vs dose. - Teaching & research on emerging technologies. ## Course Administrative Information ### Course Outline (13 Topics) 1. X-ray tube & generator. 2. X-ray spectrum. 3. X-ray interaction in human body. 4. Scattered radiation. 5. Film-screen radiography. 6. Fluoroscopy. 7. Tomography. 8. Mammography. 9. Digital radiography. 10. Quality control & testing of radiographic X-ray machine. 11. Radiographic quality (contrast, resolution, MTF). 12. Radiation hazards associated with diagnostic radiology. 13. Current developments in diagnostic radiology. ### Course Structure & Weightage - Coursework 50 % - Tests: 2 \times 7.5\% = 15\% - Assignments (4): 25\% - Quizzes: 10\% - Final Examination: 50\%

————————

Total: 100\% - “END of class briefing…” indicates administrative discussion concluded. ## Fundamentals of X-ray Production - Requires high-speed electrons suddenly decelerated in a target (X-ray tube). - Two dominant emission processes: Characteristic & Bremsstrahlung. ### Characteristic X-rays - Occur when incident electron energy Ee is greater than binding energy of an inner-shell electron Eb.

Ee > Eb \;\Rightarrow\; \text{eject inner electron} - Electron vacancy filled by outer-shell electron → discrete photon emitted:

E{\text{X-ray}} = E{\text{outer}} - E_{\text{inner}} - Energy depends on “gap” between shells; example range:

E_{K\beta} \approx 10{,}000\,\text{eV} - 100\,\text{eV} (material specific). - Spectrum lines labelled: Kα, Kβ, … - Idealised intensity chart showed sharp spikes at those energies. ### Bremsstrahlung (Braking) X-rays - Produced when incident electron is decelerated in the Coulomb field of nucleus. - Photon energy distribution is continuous from 0 to the maximum electron kinetic energy. - Probability ↑ with higher atomic number Z (denser nuclear charge enhances deceleration). - Slide examples: 40\,\text{keV}, 60\,\text{keV}, 100\,\text{keV} electron energies. - Photon energy magnitude depends on: - Deflection angle of electron. - Incident electron energy. - Distance of closest approach to nucleus. ## Composite X-ray Spectrum (Tube Output) - Superposition of: - Continuous Bremsstrahlung curve (broad). - Discrete characteristic spikes (narrow). - Graph axis: relative intensity vs photon energy (0 → 150\,\text{keV}). - Endpoint energy equals accelerating voltage (kVp). - Peak positions of characteristic lines remain fixed for a given target material. ## Ethical, Practical & Real-World Implications (highlighted implicitly) - Use of ionizing radiation mandates adherence to radiation protection principles: - Justification, Optimisation (ALARA), Dose Limitation. - Historical example (Röntgen) shows rapid clinical adoption—but emphasises need for ongoing safety oversight (medical physicist role). - Course topics on radiation hazards & quality control reinforce safety culture. ## Teasers for Future Lectures - Slides hinted at advanced imaging (fluoroscopy, tomography, mammography, digital). - Mentions of Soteria.AI, OMEGA, Cytom 16, Nosot could refer to AI or vendor systems—suggesting upcoming discussions on current developments & machine learning in radiology.