CSI - Case Study 1 - 4; tAPP

CSI 1 - Fresher’s Flu

Flu vs Common Cold

• Spread of symptoms

  • Flu is systemic whereas common cold is localised

• Symptomatic differences

  • Fever is quite common with the flu

  • Fatigue is more common with the flu

  • Diarrhea sometimes present for flu

• Onset of symptoms

  • Gradual onset for common cold

  • Rapid onset for flu

• Covid Symptoms

  • First symptom usually a fever

  • Loss of taste/smell usually present

  • Dry cough is common

Clinical Manifestations

• Causative Agents

  • Covid-19: Coronavirus

  • Common Cold: Rhinovirus, Adenovirus, Coronavirus, Influenza Virus

  • Flu: Influenza Virus

• Surface Molecules:

  • Coronavirus: ACE2

  • Influenza Virus: Sialic Acid

  • Rhinovirus: ICAM1