Bacterial cell wall
bacterial wall-Main functions include keeping cell shape (like an
exoskeleton).
Prevents cell lysis. (can withstand internal
high as water osmotic]pressure. pressosmotic floods in the
· Pressure builds.
:- the cell wall acts
-
:.......as a dam to keep
water in
.
Most bacterial cell walls comprised of peptidoglycan /made of sugar+ amino acids.
- glycan part alternates+ repeats sugars
peptido--amino acids form peptide bond cross links·
N-acetyl giucosomine (NAG)
·
connect the Chains of Sugars (NAG, NAM·
N-acetylmuranic acid (NAM)
Gramtvs . Gram-
Gram positive cells have a thick layer of peptidoglycan
· 90 % peptidoglycanand 20-80nm thick
· They have teichoic acids anchored in cell wal
Gram negative have a thin layer of peptidoglycan (onlyn 2nm)
outer membrane contains Lipopolysaccharides (LDS)* Lipid A : acts as endotoxin
Periplasm: Space between cell + outer membrane
Gram Positive+ Gram Negative Cells have different susceptibility to :
enzymes and antibiotics