Drug Subcategories of Antiviral Drug

Drug Subcategories of Antiviral Drugs

I. The Viral Growth Cycle (“A Penguin Unknowingly Entered The Late Party And Rolled.")

  1. Attachment

  2. Penetration (AAGG)

    • Antiviral Antibodies (Gamma Globulin)

  3. Uncoating (“Amazing Roosters Inspire."/TADINE; exc. Interferons/ARI)

    • AmanTADINE

    • RimanTADINE

    • Interferons

  4. Early Translation (Early mRNA and protein synthesis) (F)

    • Fomivirsen

  5. Transcription (Viral Genome Replication) (DR.)

    • Inhibitors of DNA-polymerase ( “Amazing Gorillas Find Courage Very Inspiring To Follow."/OVIR/INE; exc. Foscarnet/AGFCVITF)

      • AcyclOVIR

      • GancyclOVIR

      • FamciclOVIR

      • CidofOVIR

      • VidarabINE

      • IdoxuridINE

      • TrifluridINE

      • Foscarnet

    • Inhibitors of RNA-dependent DNA-polymerase (Reverse Transcriptase) (“Zebras Don't Swim, Zookeepers Love Fish."/INE; exc. Vidarabine, Idoxuridine, Trifluridine (DNA Polymerase Inhibitor), Foscarnet/ZDSZLF)

      • ZidovudINE

      • DidanosINE

      • StavudINE

      • ZalcitabINE

      • LamivudINE

      • Foscarnet

  6. Late Translation (Late mRNA and protein synthesis) (Rose Ivy/RI)

    • Ribavirin

    • Interferons

  7. Posttranslational Modifications (Proteolytic cleavage)

    • Protease inhibitors (NAVIR/SIR)

      • SaquiNAVIR

      • IndiNAVIR

      • RitoNAVIR

  8. Assembly (Packaging of viral nucleic acids) (Ivy Rose)

    • Interferons

    • Rifampin

  9. Release (Virion released from cell) (AACTL)

    • Antiviral Antibodies

      • Cytotoxic T lymphocytes

II. Agents to Treat Specific Viruses

  • Herpes Simplex Virus (HSV) & Varicella Zoster Virus (VZV) (“Amazing Vampires Fly Past Trees."/OVIR; exc. Trifluridine/AVFPT)

    • AcyclOVIR

    • VancyclOVIR

    • FamciclOVIR

    • PenciclOVIR

    • Trifluridine

  • Cytomegalovirus (CMV) (“Great Vikings Can Fight Fiercely."/OVIR; exc. Foscarnet, Fomiversen/GVCFF)

    • GanciclOVIR

    • ValganciclOVIR

    • CidofOVIR

    • Foscarnet

    • Fomivirsen

III. Antiretroviral Agents (“New Neighbors Need Perfect Friends.")

  • Nucleoside Reverse Transcriptase Inhibitors (NRTIs) ( “Zebras Dance, Lions Zip Swiftly Along."/INE; exc. Abacavir)

    • ZidovudINE

    • DidanosINE

    • LamivudINE

    • ZalcitabINE

    • StavudINE

    • Abacavir

  • Nucleoside Inhibitors (NIs) (T)

    • Tenofovir

  • Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) (“Never Drive Exhausted."/INE; exc. Efavirenz)

    • NevirapINE

    • DelaviridINE

    • Efavirenz

  • Protease Inhibitors (PIs) (“Singing Rhinos Leap In Nearby Airports."/NAVIR)

    • SaquiNAVIR

    • RitoNAVIR

    • LopiNAVIR

    • IndiNAVIR

    • NelfiNAVIR

    • AmpreNAVIR

  • Fusion Inhibitors (FIs) (“Enthusiastic Dolphins.”)

    • Enfuvirtide (HIV)

    • Docosanol (HSV)

IV. Anti-Hepatitis Agents (“Lazy Alligators Imagine Perfect Rivers.")

  • Lamivudine

  • Adefovir

  • Interferon alpha

  • Pegylated interferon alpha

  • Ribavirin

V. Anti-Influenza Agents (“Amazing Rhinos Zigzag Obliquely.”/TADINE/MIVIR)

  • AmanTADINE

  • RimanTADINE

  • ZanaMIVIR

  • OseltaMIVIR

VI. Other Antiviral Agents (“Playful Iguanas”)

  • Palivizumab

  • Imiquimod