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Bones and the Skeletal System Review

Skeletal System Introduction

  • The skeletal system is composed of:

    • Bones

    • Cartilages

    • Joints

  • It forms the internal framework of the body, providing support, protection, movement, and other crucial functions.

Cartilage

Location in the Adult Body

  • Aids in support of the body through cushioning.

  • It is a tough but flexible tissue that withstands twisting and compressive forces.

  • Specific locations include:

    • External ear

    • Articular cartilage (at the ends of most bones at movable joints)

    • Between vertebrae (intervertebral discs)

    • Articular discs

    • Epiglottis

    • Nose

    • Costal cartilage (connecting ribs to sternum)

    • Pubic symphysis

    • Larynx

    • Airways

Cartilage Matrix

  • Cartilage is a connective tissue with an extensive extracellular matrix (ECM).

  • It consists primarily of water, ranging from 60\% to 80\%, which allows it to return to its original shape once compressed.

  • The specific cells in cartilage are called chondrocytes.

  • Each chondrocyte resides in a space known as a lacuna.

  • Notably, cartilage contains no nervous innervation or blood vessels, making its healing process slower.

Types of Cartilage

There are three main types of cartilage in the body:

  1. Hyaline Cartilage:

    • Characterized by being flexible and resilient.

    • Found in articular cartilage, costal cartilage, and respiratory cartilage.

  2. Elastic Cartilage:

    • Highly bendable due to a high concentration of elastic fibers.

    • Located in the epiglottis and the outer ear.

  3. Fibrocartilage:

    • Designed to resist both compression and tension forces.

    • Found in the knee menisci and the annulus fibrosus of intervertebral discs.

Bones

Functions of Bones

  • Support and Protection: Provides a framework for the body and protects internal organs.

  • Levers for Movement: Serves as attachment sites for muscles and tissues, creating levers for movement.

  • Hematopoiesis: The process of blood cell production occurs within the bone marrow.

  • Storage of Mineral and Energy Reserves: Primarily stores calcium and phosphate, essential minerals for various bodily functions.

Bones as Organs

  • Bones are classified as organs because they contain several different types of tissues:

    • Bone Tissue: A specialized connective tissue with an extensive ECM composed of:

      • An organic component (e.g., cells like osteoblasts, osteocytes) for tensile strength.

      • An inorganic component (e.g., mineral salts, specifically hydroxyapatites) for hardness.

      • Bone tissue is dynamic and continuously undergoes remodeling.

      • This process involves:

        • Osteogenic cells: Stem cells that differentiate into bone-forming cells.

        • Osteoblasts: Responsible for depositing the organic material of the bone matrix.

        • Osteocytes: Mature bone cells surrounded by the matrix, maintaining bone tissue.

        • Osteoclasts: Cells responsible for breaking down bone tissue.

    • Nervous Tissue: Contains nerves that innervate the bone.

    • Blood Tissue: Contains blood vessels that supply nutrients and remove waste.

    • Cartilage: Articular cartilage is found at the ends of bones in joints.

    • Epithelial Tissue: Lines blood vessels within the bone.

Bone Shapes

  • Flat Bones: Thin and may be slightly curved (e.g., skull bones, sternum).

  • Irregular Bones: Have elaborate and complex shapes (e.g., vertebrae, hip bones).

  • Long Bones: Characterized by a shaft and two ends, longer than they are wide (e.g., femur, humerus).

  • Short Bones: Roughly cube-shaped (e.g., carpals, tarsals).

    • Sesamoid Bones: A special type of short bone that forms within a tendon (e.g., patella).

Compact and Spongy Bone

  • Compact Bone (also known as cortical bone):

    • Appears solid to the unaided eye but contains many microscopic passageways for blood and lymphatic vessels and nerves.

    • The structural unit of compact bone is the osteon (or Haversian system), a cylinder of bone tissue.

    • Found as the external layer on all bones and forms the bulk of the diaphysis (shaft) of long bones.

  • Spongy Bone (also known as trabecular bone):

    • Structural units are trabeculae, which are flat, needle-like or plate-like bone pieces that form a network of