Unit 3

Term

Explanation

Application/Example/Extension

                          Neurons

Neurons are the building blocks, or messengers, which travel throughout the nervous system allowing communication

Parts of a Neuron

Dendrites- the part of a neuron which receives information from other neurons

As dendrites grow in size, like a bush growing in size, then communication between neurons will be quicker because neurotransmitters do not travel very far to the next neuron.  Neurons don’t regenerate

Axons- part of a neuron where neural impulses take place, which enables information to be sent to other neurons

The longest part of a neuron

Myelin sheath- insulates, or covers the axon, which helps to speed up communication

When myelin sheath starts to disintegrate, or disappear then multiple sclerosis could develop

Nodes of Ranvier- are gaps in the myelin sheath

Neurotransmitters- chemical messengers that travel across a synapse from one neuron to another influencing whether an action potential will occur 

Synapse- the gap between neurons that neurotransmitters cross

          How Neurons Communicate

Neurons are able to communicate through an action potential, which is a brief electrical charge that travels through a neuron allowing a neurotransmitter, or messenger, to exit the neuron and go to another neuron

Neural Impulse

(action potential)

Resting potential- each neuron sits, or rests at a   -70 charge, which is the only time the neuron is capable of firing an action potential

Like the water in your toilet at a constant level waiting to be flushed.

Process Begins












Process Finishes

Depolarization- a message from another neuron causes the inside of the neuron to become positive as sodium starts to enter 

Threshold- through the process of depolarization the inside becomes positive; once this charge exceeds the threshold, which is the minimum level of stimulation necessary to cause an action potential, then the neuron fires.

Think about the threshold as the height requirement to ride an amusement park roller coaster.  If you are above the height line then you can ride (same as a charge being above the threshold) allowing an action potential to occur

All-or-none potential- a neuron will fire each time with the same amount of intensity

Similar to when you fire a gun- the bullet comes out the same way every time you pull the trigger

Repolarization- occurs right after the action potential as potassium moves out of the inside of the cell restoring the inside back to a negative charge 

Think about RE-polarization as RE-storing the charge back to -70

Hyperpolarization- occurs right after the process of repolarization because the inside of the cell’s charge becomes too low, or below the -70 charge. 

Hyperpolarization is referred to as a refractory period, as during this period the neuron can’t fire until the charge returns back to -70

A refractory period is similar to the moment after you flush a toilet- until the water returns back to its original level you can’t flush again, similar to a neuron returning back to -70 before it can fire another action potential

Excitatory message- makes it more likely the neuron will depolarize, causing an action potential

Inhibitory message- makes it more likely neuron will hyperpolarize, not causing an action potential

Remember excitatory means to EXCITE- when the neuron becomes excited it fires an action potential.

Inhibit means to stop, or slow down an action potential

  Nervous Systems                 

Central nervous system

Includes the brain and spinal cord

Interneurons- neurons located within and only travel and communicate in the central nervous system

Remember the spinal cord in centrally located in your body

Peripheral nervous system

The Peripheral nervous system connects the body to the central nervous system

Parts of the Peripheral Nervous System

Somatic nervous system- part of the peripheral nervous system which controls voluntary movements

An example of the somatic nervous system would be moving your arm- you are voluntarily moving your arm

Autonomic nervous system- part of the peripheral nervous system which controls involuntary movements

An example of the autonomic nervous system is your heart rate, which occurs involuntary or automatically

Parts of the Autonomic nervous system

Sympathetic nervous system- part of the autonomic nervous system that speeds up the body

An example of the sympathetic nervous system would be your heart racing, or speeding up as you almost get into a car accident. 

S-ympathetic= S-peed up the body

Parasympathetic nervous system- part of the autonomic nervous system that calms the body down

An example of the parasympathetic nervous system would be your heart-rate retuning back to its normal rate as the accident is over.

P-utting back heart rate= P-arasympathetic  

Neurons and Nerves

Neural Chain- how the brain communicates with the body

Sensory neurons- are neurons that travel within the peripheral nervous system and sense information from the environment

Interneurons- are neurons that communicate within the central nervous system

Motor neurons are neurons that travel within the peripheral nervous system; carry information out to muscles and glands, causing movement

Presynaptic neuron- neuron that sends, or releases a neurotransmitter

Reuptake- presynaptic neuron absorbs back excessive, or unused, neurotransmitters in the synapse 

Reuptake process is like a vacuum- the sending neuron sucks back excessive NTs to later be used- if NTs stay in the synapse for a period of time, then problems could occur, like depression.

Postsynaptic neuron- neuron that receives a neurotransmitter

Nerves are neural cables, or “roads,” comprised of axons that are part of peripheral nervous system, which enable communication back to the central nervous system

Nerves are like ropes.  Ropes are intertwined with string and nerves are intertwined with axons.

Afferent nerves- carry information TO the central nervous system

Sensory neurons- neurons that travel within afferent nerves and SEND information to the central nervous system

Remember the word SAME

Sensory neurons travel through Afferent nerves

Motor neurons travel through Efferent nerves






Efferent nerves- carry information FROM the central nervous system

Motor neurons- neurons that travel within efferent nerves and carry information AWAY from the central nervous system

Tie it all together:

If you were to put your finger in hot water (1) a sensory neuron would detect this hot water travel through an afferent nerve up the peripheral nervous system, towards the central nervous system where (2) an interneuron would take the information, then the brain would process the information, releasing (3) a motor neuron that would travel through an efferent nerve back down the peripheral nervous system, causing your finger to pull out of the hot water.

                                            Types of Neurotransmitters

Neurotransmitter

Function

Problems 

Acetylcholine

Muscle action, learning, memory

Lack of can lead to Alzheimer’s disease 

Dopamine

Learning, attention, emotion- pleasure

Too much dopamine leads to schizophrenia, and too little dopamine could lead to Parkinson’s disease

Serotonin

Mood, hunger, sleep, arousal

Lack of linked to depression

Norepinephrine

Alertness and arousal

Lack of linked to depression

GABA

Inhibitory neurotransmitter- slows down brain activity

Lack of linked to seizures, tremors, and insomnia

Glutamate

Major excitatory neurotransmitter- involved in memory

Too much could lead to migraines or seizures

Endorphins

Pain control and pleasure

Too much pain medication could lead to lack of endorphin supply

Drugs that affect

Neurotransmitters

Agonist is a drug designed to mimic, or perform the same actions as a neurotransmitter- often used when there is not enough of a neurotransmitter

Agonist is like a key that fits a lock and is able to unlock it- the same as an agonist fitting the receptor site of a neuron and mimicking the NT

Antagonist is a drug designed to block a neurotransmitter- often used when there is too much of a neurotransmitter

Antagonist is like a key that fits a lock but does not turn the lock, hence not opening the door- the key is now stuck in the lock, preventing any other key from entering

  Endocrine System







The endocrine system is another type of communication system that uses a set of glands which produce hormones (like neurotransmitters) that circulate through the bloodstream, enabling communication. 

The endocrine system uses the bloodstream making it much slower than the nervous system, which uses electricity

Hypothalamus- part of the brain that links the brain to the endocrine system through control of the pituitary gland

Pituitary gland- “master gland” that controls all other glands

Think of the pituitary gland as “master P”

Thyroid gland- involved in metabolism

Adrenal glands- help trigger “fight-or-flight” response

                    Parts of the Brain

Brainstem- oldest part of the brain; responsible for survival; comprised of the hindbrain and midbrain

If you were to look at a car seat you would notice that it is positioned to hit the top part of the heard, rather than the brainstem, as this could cause serious-to-fatal injury.

Midbrain- controls certain types of automatic behaviors

Hindbrain- an extension of spinal cord involved in blood pressure, heart rate, breathing, and other vital life functions; includes the medulla, reticular formation, cerebellum, and pons

Medulla- controls heartbeat and breathing

Reticular formation- controls wakefulness and arousal

“Pay particular (reticular) attention”

Cerebellum- coordinates movements, balance

Sara-bellum has good balance”

Pons- coordinates movements on the left and right side of the body; dreams

Think about playing ping PONg- hitting back and forth as the pons controls right and left movements

Forebrain- responsible for complex behaviors and mental abilities

Hypothalamus- maintains eating, drinking, body temperature

“The man’s part of the brain”- loves pizza and beer 

Limbic system- regulates memory, fear, aggression, hunger, and thirst

“My emotions are in LIMBO

Hippocampus- processes new memories

Hippos have great memory

Amygdala- linked to fear and emotion

“Don’t ever make AMY mad”

Thalamus- relay center for sensory information except smell

The “secretary” of the brain- sends information to proper place.

Cerebral cortex- most sophisticated area of the brain

Very similar to a CPU unit of a computer- the processor

Cerebral hemispheres- the left and right side of the cerebral cortex 

Corpus callosum- connects the two hemispheres 

Like a cord that connects two computers

Split-brain- refers to people who have had their corpus callusum severed/ Roger Sperry found to reduce epileptic seizures

Each hemisphere is divided into four lobes.

Association areas are present on all 4 lobes and are responsible for higher mental functions such as learning, speaking, remembering, and thinking

Frontal lobes- largest lobe- involved in planning, thinking, emotional control, and muscle movement

People will often hit themselves in the front of the head and say, “I am so stupid”- makes sense- it is the thinking portion of the brain.

Motor cortex- controls voluntary movements

The right hemisphere controls the left side of the body and the left hemisphere controls the right side of the body

Parietal lobes- located top of the hear- processes body information- touch

In duck-duck-goose people “pat” others on the top of the head

Occipital lobes- located back of the head- processes visual information

Think about the eye store, D.O.C. cipitial, or remember, “O-h, I C (see)

Temporal lobes- processes auditory information

You listen to the “tempo” or the beat

  Spatial ability       and   Language

Lateralization- notion that each hemisphere is responsible for specific abilities and tasks

Right hemisphere- handles nonverbal- spatial, musical, and visual- recognition tasks

Left hemisphere processes language which includes the Broca’s and Wernicke’s areas

Broca’s area- involved in spoken language

Think about “boco” in Spanish- means mouth, or “broken” speech

Wernicke’s area- processes the ability to understand language, communication

Think about Professor Wernicke- no one can understand him

Aphasia- refers to the inability to speak or understand

It is possible for someone to not be able to speak- Broca’s aphasia, but understand and vice versa.

Imaging the brain

CAT Scan- X-ray photographs of the brain

MRI- uses magnetic fields that produce computer images of the brain

EEG- measures electrical activity of the brain- often used to measure brain waves during sleep

PET scan- measures brain activity through injecting radioactive glucose while the brain is performing functions

Lesioning- involves destroying a piece or part of the brain