Genetics Study Guide

Gregor Mendel

  • Known as 'The Father of Genetics'.

Key Terminology

  • Homozygous: An organism with two of the same alleles for a particular trait.
  • Heterozygous: An organism with two different alleles for a particular trait.

Fundamental Laws of Genetics

  • Law of Segregation: States that two alleles for each trait separate during meiosis.
  • Law of Independent Assortment: Indicates that genes on separate chromosomes sort independently during meiosis.

Pedigree Functions

  • Function of a Pedigree: A diagram that traces the inheritance pattern of a particular trait through generations.

Inheritance Patterns

  • Codominance: A genetic scenario where both alleles for a trait are fully expressed.
    • Example: Type AB blood, where both A and B alleles are expressed equally.
  • Incomplete Dominance: Occurs when the resulting phenotype is a blend of both parental traits.

Sickle Cell Trait and Malaria

  • In central Africa, high malaria rates result in the heterozygous state being protective; individuals with one sickle cell allele are resistant to malaria.

Genetic Complexity

  • Multiple Alleles: The presence of more than two alleles for a genetic trait.
  • Epistasis: The interaction of alleles, where one allele can mask the effects of another allele.

Sex-Linked Traits

  • These are influenced by genes located on the X chromosome, with examples including red-green color-blindness.

Polygenic Traits

  • Traits controlled by more than two genes have a polygenic inheritance pattern; an example is skin color, which is influenced by multiple gene pairs.