Introduction to Biology: The Chemistry of Carbon

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THE CHEMISTRY OF CARBON

Learning Goals

  • Atoms

    • Define what atoms are.

    • Describe their structure.

    • Explain how they bond.

  • Water

    • Understand water's features that support all forms of life.

  • Carbohydrates

    • Describe the structure and function of carbohydrates.

  • Lipids

    • Describe the structure and function of lipids.

  • Proteins

    • Describe the structure and function of proteins.

  • Nucleic Acids

    • Describe the structure and function of nucleic acids.

BIO 111 INTRODUCTION TO BIOLOGY

Opening Roadmap

  • Chemistry is intimately linked to the evolution of life.

  • Key questions addressed:

    • How are atoms, ions, and molecules structured and bonded?

    • How do chemical reactions occur?

  • Key areas of focus:

    • 2.1: Atoms and their structure.

    • 2.2: Unique properties of water.

    • 2.3: Chemical bonding in molecules.

    • 2.4: Carbon's role in life.

    • 2.5: Evolution of life.

WHY STUDY CARBON?

  • Carbon Compounds in Living Organisms:

    • Plants, algae, and many bacteria are classified as autotrophs, contributing to 25% of body carbon compounds, comprising:

    • Proteins/Enzymes

      • Organic compounds made up of carbon forms.

    • Carbohydrates

      • Comprising carbon, oxygen, and hydrogen.

    • Lipids

      • Comprising carbon and hydrogen mainly.

    • Nucleic Acids

      • Essential for genetic information.

    • Animals, fungi, and many bacteria are heterotrophs that rely on these compounds.

MATTER AND ELEMENTS

Properties of Carbon

  • Origin of the Name: Latin "carbo" means coal.

  • Atomic Information:

    • Atomic Mass: 12

    • Atomic Number: 6

    • Symbol: C

  • Significance:

    • Fourth most abundant element in the universe.

    • Non-metallic, tetravalent atom capable of forming four bonds.

  • Carbon Isotopes:

    • Common Isotopes:

    • 12C^{12}C

    • 13C^{13}C

    • 14C^{14}C

BONDS AND STRUCTURES OF CARBON

Carbon Bonding

  • Carbon forms four covalent bonds, allowing for various structures:

    • Single Bonds:

    • e.g., H<em>3CCH</em>3H<em>3C - CH</em>3 (Alkane structure)

    • Double Bonds:

    • e.g., C=CC=C (Alkene structure)

    • Triple Bonds:

    • e.g., CripleCC riple C (Alkyne structure)

Hydrocarbons

  • Definition: Hydrocarbons are compounds consisting solely of carbon and hydrogen.

  • Types:

    • Methane (CH₄): Simplest hydrocarbon, non-polar and hydrophobic.

    • Alkanes, Alkenes, and Alkynes: Varieties of hydrocarbons distinguished by the type of bonds between carbon atoms.

Chain and Structure Variations

  • Hydrocarbons can vary in:

    • Length (e.g., Ethane, Propane, Butane)

    • Branching (e.g., Isobutane)

    • Double Bonds (e.g., 1-Butene, 2-Butene)

    • Rings (e.g., Cyclohexane, Benzene)

Implications of Bond Types

  • Certain bond types lead to:

    • Planar Molecular Structures: No rotation around double bonds (e.g., ethylene and acetylene).

MOLECULAR DIVERSITY

Structural Variation in Hydrocarbons

  • Ethane (C₂H₆) vs. Ethanol (C₂H₅OH)

    • Functional groups substitute hydrogen atoms to confer different biological effects.

Functional Groups

  • Definition: Groups of atoms that confer specific properties to organic compounds.

  • Types:

    • Hydroxyl (-OH): Forms alcohols.

    • Carbonyl (C=O): Includes aldehydes and ketones.

    • Carboxyl (-COOH): Found in fatty acids and amino acids; characterized by inherent acidity.

    • Amino (-NH₂): Acts as a base, typically found in amino acids.

    • Phosphate (-PO₄): Highly reactive and involved in energy transfer.

BIOMOLECULAR SIMILARITIES AND DIFFERENCES

Steroisomers

  • Molecules can have the same molecular formula but differ in structure and function (e.g., L-DOPA vs. D-DOPA).

Hormonal Structures

  • Basic structure of male (Testosterone) and female hormones (Estrogen) is similar but differs at functional groups that affect reactivity and biological function.

CONCLUSION

  • The diverse nature of carbon and its compounds underlies the complexity and adaptability of biological systems in living organisms on Earth.