Quiz 1 Content (1st 2 weeks)

Neuron

  • leaky bags of charged liquid
  • some - cell body
  • dendrites - input
  • axon - output
    • myelin sheath
    • axon terminals

Action Potential

  • -70mV across neurons membrane
  • neurons depolarize to fire and AP
    • depolarization at -55mV
    • then refractory period happens
  • BCIs record or stimulate action potentials

 

The Synapse

  • axon teminal → synaptic cleft → dendrite
  • presynaptic neuron → post synaptic neuron
    • between:
    • receives neurotransmitters from dendrites
    • generates and action potential
    • releases neurotransmitters from axon terminal

Nervous System

  • PNS
    • Somatic
    • skeletal muscles, sensory organs
    • Autonomic
    • pumping heart, breathing
  • CNS
    • brain
    • spinal cord

Brain Anatomy

  • composed of many nuclei (clusters of neurons)
  • separated into 2 cerebral hemispherse
  • has both distributed and localized neural networks
  • Frontal Lobes:
    • voluntary movement, expressive language, higher level executive functions (future plans, judgment, decision making, inhibition, attention span)
    • not developed until late 20s
  • Parietal Lobes:
    • sensory processing (touch, pressure, hot/cold, pain), navigation + control, judging size shape + distance, symbol interpretation (math, spoken language, writing)
    • useful for judgement or size, distane and shapes’
    • understand math problems and handwriting
  • Temporal Lobes:
    • auditory info, emotions, language, visual perception, encoding memory
    • Determines L/R dominance
    • Dominant left (most people) - understand language, learning, remembering verbal info (right-handed)
    • Non-dominant right (most people) - learn and remember non-verbal info (music)
    • Wemicke’s and Broca’s area- Speech recognition
  • Occipital Lobes:
    • Primary visual corex
    • color interpretation, visual receiving and association
    • Ventral and Dorsal streams
    • ventral - “what” of vision
    • dorsal - “where/how” of vision

Homunculus

  • somatosensory - what you feel
  • motor - voluntary motion
  • represents either motor or sensory distribution along the cerebral cortex of brain

10-20 system

  • EEG - detects cortical neuron activity near electrodes
  • EEG standardization:
    • allows for result validation in independent trials
    • scalable to different skulls, helps pinpoint brain areas
  • Even numbers = right
  • odd numbers = left
  • Terms:
    • C - central
    • P - parietal
    • T - temporal
    • F - frontal
    • Fp - frontal polar
    • O - occipital
    • A - mastoids
    • Naison - top of nose
    • Inion - base of skull
  • 10-20 stands for 10% and 20% intervals between naison and inion

10-10 system

  • increases accuracy with more nodes

How are EEG’s recorded?

  • Take bipolar montages → subtract down he cap → 5 electrodes = 4 signals outputted
  • the differential amplifier used → subtracts input 1 and input 2 → subtraction is outputted

The Bands of an EEG

  • Delta band → 1-3 Hz
    • deep sleep, motivational process
    • highest amplitude, slowest wave
  • Theta band → 4-7 Hz
    • memory and emotional regulation
    • encoding of info during exploratory movements and spatial navigation
    • salience detection
  • Alpha band → 8-12 Hz
    • visual input, perceptual awareness
    • inverse relation to cortical activation
    • plays role in inhibiton
    • eyes closed = inc amplitude
    • eyes open = dec amplitude
  • Beta band → 13-30 Hz
    • decrease during voluntary movements
    • bursts after the act is complete
    • same response when imagining movement
    • plays role in attentive behavior
    • serves as a carrier for attentional activation
    • alertness or arousal → allows perception of stimuli
  • Gamma band → 30-100 Hz
    • construction of object representation
    • increased → complex/demanding tasks
    • bind spatially distinct features of visual objects
    • reflect associations between words and meanings
    • integration of sensory and motor processes during movement