I. The Science of Biology
Characteristics of Life (MRS GREN):
Movement:
Respiration:
Sensitivity:
Growth:
Reproduction:
Excretion:
Nutrition:
Basic Theories of Modern Biology
Cell Theory (All Cells Pre-exist):
Cells are the basic unit of life.
All cells come from pre-existing cells.
All metabolism occurs in cells.
Gene Theory (DNA Rules Everything):
Genetic info is stored in DNA (genes).
Genes control aspects of an organism.
DNA transcribed to RNA, translated to protein.
Homeostasis:
Living organisms maintain constant internal environment.
Purpose: Ensure proper body function.
II. Chemical Basis of Life
Cell Organelles & Functions (My Very Energetic Mother Just Served Us Nachos):
Mitochondria: Powerhouse.
Vacuole: Storage
Endoplasmic Reticulum: Transports materials.
Microtubules: Cell Shape
Junctions: cellular connection
Solgi appartus: Packages and Modifies.
Uh oh sorry guys
Nucleus: Control center.
Cell Membrane: Lipid bilayer for protection, communication, selective exchange.
Passive Transport (DownHill): Osmosis, diffusion, facilitated diffusion (high to low concentration).
Active Transport (UpHill): Movement against natural diffusion.
Cell Types:
Prokaryotes: Bacteria (DNA, ribosomes, cell membrane, NO organelles).
Eukaryotes: Animals & Plants (organelles, cell membranes).
Plants also have chloroplasts & cell walls.
Atoms: Electrons, neutrons, protons.
Molecules: Formed by atoms joined by chemical bonds.
Chemical Bonds:
Ionic Bond (Electron Thief): Atoms lose or gain electrons.
Covalent Bond (Electron Share): Atoms share electrons (strong, in organic chemicals).
Hydrogen Bond (Weak Attraction): Weak electrical attraction between molecules.
Buffers: Resist pH change.
pH: Concentration of hydrogen ions [H^+]
Organic Molecules (CLuNP): Carbohydrates, Lipids, Nucleic Acids, Proteins
III. Cellular Respiration
Aerobic Respiration (Oxygen Required):
Glycolysis (Splitting Glucose): Glucose broken down into pyruvate (2 ATP).
Krebs Cycle (Energy Extraction): Acetyl CoA cycles, electrons passed to NADH & FADH2 (2 ATP).
Oxidative Phosphorylation (ATP Production): 32 ATP produced.
Anaerobic Respiration (No Oxygen):
Glycolysis (Splitting Glucose): Glucose to pyruvate (2 ATP).
Fermentation (Recycling Glycolysis): Pyruvate broken down into ethanol or lactic acid.
Metabolism (Life Chemical Reactions): Chemical reactions for life.
Anabolism (Building Up): Construction of molecules (protein synthesis, glycogenesis).
Catabolism (Breaking Down): Breakdown of molecules (glycolysis, beta oxidation).
IV. Photosynthesis
Chloroplast: Organelle in plant cells where photosynthesis occurs.
Photophosphorylation (ATP Light): ATP generated via light reactions.
Light Reaction (Light Energy): Light harvested, electron transfer occurs (ATP, NADPH, O2 generated).
Dark Reaction (Calvin Cycle or Carbon Fixation): CO2 fixed, carbohydrates generated (ATP & NADPH consumed).
Chlorophyll: Proteins in chloroplasts that absorb sunlight.
V. The Cell Cycle (IPMAT):
(I Pee More At The Toilet)
Interphase
Prophase: Chromosomes condense, nuclear envelope breaks down, centrioles move.
Metaphase: Chromosomes line up in the middle, spindle fibers attach.
Anaphase: Sister chromatids separate and move to opposite sides.
Telophase: Chromosomes dissolve, nuclear envelopes reform.
Checkpoints (Guarding The System): G1, S, G2, M (ensure proper progression).
VI. Introduction to Ecology
Ecology (Eco-Living): Study of organisms and environment.
Organisms show behavioral, physiological, morphological responses to the environment
Environment (ALIVE): Abiotic, Living Interactions Value Earth Abiotic (non-living) and biotic (living) factors.
Abiotic: Temperature, water, light, soil, wind, fire.
Biotic: Plants, animals.
Ecological Levels (Big Cats Play In Parks):
Biosphere: Entire portion of Earth inhabited by life.
Biomes: Major communities with similar vegetation.
Community: Group of populations in the same area.
Population: Group of individuals of the same species.
Producers: Green plants capturing sunlight.
Consumers: Organisms that eat other organisms.
Food Web: Complex feeding relationships.
Chemical Cycling: Transfer of energy between forms.
VII. Communities, Ecosystems, and Biomes
Ecological Succession:
Primary Succession (New Life): Life begins where none existed before.
Secondary Succession (Life Returns): Change in species composition.
Aquatic Ecosystems: Oceans, lakes, streams, rivers, estuaries.
Terrestrial Biomes: Ecosystems sharing climate, flora, fauna.
Community Interactions (CPM):
Competition (interspecific, competitive exclusion principle).
Predation (plant/animal defenses).
Symbiosis: Parasitism, Commensalism, Mutualism
Ecological Niche:The role and position a species has in its environment; how it meets its needs for food and shelter, how it survives, and how it reproduces
VIII. Population Ecology
Population: Group of individuals of a species in a specific area.
Population Density: Individuals per unit area.
Dispersion (CUR): Pattern of spacing within population (clumped, uniform, random).
Population Range: Geographic limits of a population.
Absolute density vs. Ecological density
Habitat Selection: Behavior of animals moving toward specific microenvironment.
Limiting Factors:
Density-independent: Weather, natural disasters.
Density-dependent: Parasitism, predation, human activities, disease, competition.
IX. Conservation Ecology
Reforestation: Development of forest in deforested area.
Conservation: Safeguarding, maintaining natural resources.
Resources: Materials satisfying human needs.
Plant and animal wealth, land, soil, air, minerals, water, energy.
Types of Resources (CNR):
Continuous Resources
Renewable Resources
Non-renewable Resources
X. Genetics
Chromosome: Functional unit of heredity, contains DNA.
Meiosis: Reproductive process producing unique haploid cells (gametes).
Haploid & Diploid: 1 Copy, 2 Copies
Dominant/Recessive Alleles (Strong Over Weak): If present, the dominant allele appears in the phenotype.
Co-Dominance (Both Expressed): Both dominant alleles show up in the phenotype.
Incomplete Dominance (Blend): Phenotype is a mix of the two alleles.
Polygenic Traits (Many Genes): Multiple genes combine to create a trait.
XI. Nucleic Acids
DNA (Genetic Code):
Cellular genetic material.
Two strands with base pairing (A-T, C-G).
Anti-parallel double helix.
RNA Classes (mTRN): Copies info from DNA.
mRNA: Copies info from DNA.
tRNA: Carries amino acids.
rRNA: Component for ribosome.
ncRNA: Regulates cellular processes.
The Central Dogma (DMRProt): DNA → mRNA → Protein
Transcription (DNA copy): RNA polymerase reads DNA, produces pre-mRNA, which is then spliced into mRNA.
Translation (mRNA decode): Ribosomes read mRNA, tRNA brings amino acids to produce proteins.
XII. The Human Genome
Genetic Disorder: Disease caused by DNA at birth.
Autosomal-Recessive (Both parents):
Sex-Linked
Autosomal-Dominant all it takes is one copy
Genetic Engineering
Bacterial Cells (insert into plasmid)
Plant Cells (insert engineered DNA, infect with virus)
Animal Cells (inject into egg nucleus)
XIII. Evolution
Heritable Adaptation: Inherited trait leading to reproductive advantage.
Punctuated Equilibrium: Rapid evolutionary changes followed by stabilization.
Natural selection:
Differential reproductive success of species carrying particular traits
Survival of the “Fittest”. Fit refers to best fit to environment
Random Variation of traits in a population
Adaptation more offspring carrying advantageous traits
Interaction of species with environment
XIV. Evolutionary History
Precambrian Time: 99% of Earth’s history, aquatic life.
Paleozoic Era: First invertebrates and vertebrates, movement onto land.
Mesozoic Era: Age of Reptiles, dinosaurs, mammals appeared.
Cenozoic Era: Age of Mammals, humans appeared.
XV. Classification
Taxonomy: Study and classification of organisms.
Animalia: Kingdom of heterotrophic consumers.
Binomial Nomenclature: Genus and species naming system.
Phylogeny: Classifying organisms based on evolutionary relationships.
Five Kingdom System: Monera, Protista, Fungi, Plantae, Animalia
XVI. Bacteria and Viruses
Bacteria: Smallest prokaryotes.
Binary Fission: Asexual reproduction in prokaryotes.
DNA Transfer Methods (ConTransTrans):
Conjugation (sex pilus)
Transformation (uptake of dead bacteria's DNA)
Transduction (virus mediated)
Oxygen Requirements (AOF):
Obligate Anaerobes (no oxygen)
Facultative Anaerobes (with or without oxygen)
Aerobic (require oxygen)
Viral Life Cycles:
Lytic Cycle (kills host cell)
Lysogenic Cycle (integrates into host DNA)
Virus Structure: Capsid, Genetic Material, Tail Fibers
XVII. Plants
Transpiration: Evaporation pulls water from roots via stomata.
Plant vs. Animal Cells:
Cell wall (cellulose in plants)
Large central vacuole (structure support)
Chloroplast (photosynthesis)
Plant Structures (Leaves Stem Root):
Root (anchors, absorbs nutrients)
Stem (support, transport)
Leaves (photosynthesis, transpiration)
XVIII. The Nervous System
Neuron Components (Dendrites Axon):
Dendrite
Cell Body
Axon
Terminal Branches
Neurotransmitter: Carries information to the next neuron.
Nervous System Divisions:
Central (Brain, Spinal Cord)
Peripheral (Motor, Sensory)
Autonomic (Sympathetic, Parasympathetic)
Somatic
XIX. The Skeletal, Muscular, and Integumentary Systems
Muscle Types (Skeletal Smooth Cardiac):
Skeletal Muscle (striated, voluntary, attached to bones)
Smooth Muscle (not striated, involuntary, intestines)
Cardiac Muscle (striated, heart)
Actin and Myosin are proteins involved in muscle contraction
XX. Respiratory and Circulatory Systems
Respiratory System: Gas exchange.
Circulatory System: Delivers oxygenated blood.
XXI. Digestive and Excretory Systems
Digestive System Processes (IDEA):
Ingestion (mouth, esophagus)
Digestion (stomach, liver, pancreas)
Absorption (small/large intestine)
Elimination (rectum)
Excretory System (Skin Lung Liver Kidney):
Skin (excretes urea)
Lungs (excretes CO2)
Liver (detoxifies compounds)
Kidneys (filters blood)
XXII. Endocrine and Reproductive Systems
Key Glands:
Hypothalamus (controls pituitary)
Pituitary (signals other glands)
Thyroid (thyroxine, metabolism)
Parathyroid (calcium levels)
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