1.1 Intro to the Human Body: Levels of Structural Organization and Major Body Systems
Levels of Structural Organization
The human body is organized from simple to complex levels of structural organization.
Foundational idea: understanding how the body is built helps explain how it functions as a coordinated whole.
Starting point: chemical level, the most basic level of organization.
Chemical Level
Atoms are the smallest units of matter that retain chemical properties.
Examples of atoms/elements in the human body: carbon (C), hydrogen (H), oxygen (O), nitrogen (N).
When atoms join, they form molecules such as:
Water (H2O)
Oxygen gas (O2)
Carbon dioxide (CO2)
Molecules link into larger structures called macromolecules, including:
Proteins
Lipids
Carbohydrates
Nucleic acids (e.g., DNA)
These chemical building blocks form the raw materials of life and lay the foundation for all subsequent levels of organization.
Cellular Level
Cells are the smallest living units capable of carrying out basic life processes (metabolism, growth, reproduction).
The human body contains many different cell types, each with specialized structures and functions:
Muscle cells contract to produce movement.
Nerve cells transmit electrical signals.
Skin cells form protective barriers.
Despite shared features, specialization among cells enables the body to function as a coordinated whole.
Tissues are groups of similar cells that perform coordinated functions.
Tissue Level
Four main tissue types:
Epithelial tissue: covers body surfaces, lines hollow organs and cavities, forms glands.
Connective tissue: supports, binds, protects structures; stores energy, transports substances; rich in blood vessels.
Muscle tissue: responsible for movement; contracts to move; generates heat; includes skeletal (voluntary), smooth, and cardiac (involuntary) muscle.
Nervous tissue: body’s communication system; conducts nerve impulses to regulate activities.
Tissues combine at the organ level to perform complex tasks.
Organ Level
An organ contains at least two types of tissues, and most contain all four tissue types.
Examples:
Heart: pumps blood via coordinated muscle contractions; lined with epithelial tissue; supported by connective and nervous tissues.
Skin: the largest organ; protects, senses, regulates temperature; composed of layers of epithelial, connective, muscle, and nervous tissues.
Organs work together within organ systems to perform major functions.
System Level
Organ systems: teams of specialized organs collaborating to keep the body functioning.
Examples:
Digestive system: mouth, stomach, intestines, and more; breaks down food, absorbs nutrients, eliminates waste.
Respiratory system: lungs, trachea, diaphragm; exchanges O2 and CO2 for cellular respiration.
Some organs participate in more than one system (e.g., the hypothalamus).
Hypothalamus is part of the nervous system and also regulates the endocrine system by controlling the pituitary gland.
Final level: organismal level, the entire human body functioning as an integrated living being made up of trillions of coordinated cells.
Organismal Level
The organismal level focuses on how the body operates as a single living individual.
Emphasizes integration and coordination among all systems to maintain life and health.
Overview of the 11 Major Body Systems
The body operates as an integrated whole; systems constantly communicate and coordinate.
Integumentary system: skin, hair, nails.
Functions: protects the body, regulates temperature, detects sensations.
Skeletal system: bones and joints.
Functions: supports, protects organs, enables movement with muscles, stores minerals, produces blood cells.
Muscular system: mainly skeletal muscle (voluntary); includes smooth and cardiac muscles (involuntary).
Functions: enables movement, maintains posture, produces heat.
Nervous system: brain, spinal cord, nerves.
Functions: processes information, sends nerve impulses, enables rapid responses, maintains vital regulation.
Endocrine system: hormone-producing glands (e.g., hypothalamus, pituitary, thymus).
Functions: regulates growth, metabolism, reproduction; hormones have slower but longer-lasting effects than nervous signals.
Cardiovascular system: heart and blood vessels.
Functions: circulates blood, delivers oxygen and nutrients, removes waste.
Lymphatic and immune systems: defend against disease, return excess fluid to blood.
Key components: lymph nodes, spleen, various immune cells.
Respiratory system: primarily the lungs.
Functions: gas exchange, oxygen intake, carbon dioxide removal.
Digestive system: mouth, esophagus, stomach, small intestine, large intestine, and related organs.
Functions: breaks down food into absorbable nutrients; absorbs nutrients; eliminates waste.
Urinary system: kidneys, ureters, bladder, urethra.
Functions: filters blood, forms urine; regulates water balance, electrolytes, and pH.
Reproductive system: organs involved in offspring production.
Examples: ovaries, testes, uterus, and related structures.
Characteristics of Living Organisms
All living organisms share a defined set of characteristics:
Metabolism: all chemical reactions in the body.
Includes catabolism (broken down to release energy) and anabolism (building up complex molecules and storing energy).
Relationship: metabolism can be viewed as the balance of catabolic and anabolic processes; often summarized as a combined framework for energy flow and material transformation.
Formal note: M = C + A where M is total metabolism, C represents catabolic reactions, and A represents anabolic reactions.
Responsiveness (irritability): ability to detect and respond to internal or external changes.
Movement: motion of the whole body and internal movements (e.g., blood flow, organ contractions).
Growth: increase in size due to cell growth or cell replication.
Differentiation: unspecialized cells become specialized (e.g., stem cells becoming neurons or muscle cells).
Reproduction: formation of new cells for growth or repair via cell division, or production of a new organism via fertilization to form a zygote.
These characteristics distinguish living organisms from non-living matter and explain how complex systems like the human body adapt, survive, and maintain homeostasis.