Lecture 20 Photosynthesis 3 Dark reactions, intro to glycolysis and cellular respiration_2_0
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HW #11: Due today by 11:59 PM, posted in Week 12 module.
HW #12: Due 11/19 by 11:59 PM, posted in Week 13 module.
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Covers material from lectures #13 - #18.
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Today's Topic
The Dark Reactions (In detail)
Relevant Reading: Chapter 8
Light Reactions Overview
Components:
Stroma
Thylakoid Membrane
Light Energy
Chlorophyll Reaction Center
H2O splitting produces 1/2 O2, including protons (H+).
Process:
Linear Electron Flow (LEF):
Produces about 1.2 ATP per NADPH.
Dark reactions utilize approximately 1.5 ATPs per NADPH.
Requires additional ATP production.
Cyclic Electron Flow (CEF)
CEF Process:
Instead of reducing NADP+, electrons from PS1 return to the proton pump.
Increases ATP production for use in dark reactions.
Dark Reactions (Calvin Cycle)
Location: Occur in the stroma of the chloroplast.
Requirements: NADPH & ATP (from light reactions), CO2.
Three Steps:
Carbon Fixation: Converts CO2 into organic form (PGA).
Reduction of PGA: Electrons from NADPH reduce PGA into G3P.
Regeneration of RuBP: Necessary for the carbon fixation step.
Carbon Fixation Details
Initial Components: RuBP (5-C sugar, carbon acceptor) and CO2.
Process:
RuBP & CO2 bond to form a 6-C intermediate.
This is catalyzed by Rubisco enzyme.
The 6-C intermediate splits into two 3-C PGA molecules.
More on Rubisco
Rubisco:
Most abundant enzyme globally (~20 lbs per human).
Fixes about 100 billion tons of CO2 annually (200 trillion lbs).
Reduction of PGA
Using:
NADPH (electron source).
ATP (energy source).
Conversion:
PGA is reduced to G3P.
G3P Functions:
Used for glucose synthesis.
Used for RuBP regeneration.
Summary of Dark Reactions
Key Components:
Enzyme: Rubisco.
Produces a 6-C intermediate that breaks down into two 3-C PGA molecules.
G3P derived from NADPH electrons and ATP energy.
Some G3P used for glucose, others for regenerating RuBP.
Beyond Glucose Production
Dark Reactions Yield:
More than just glucose, including other sugars, amino acids, lipids, and nucleic acids.
Glucose as a Fuel Source
Energy Content:
Glucose: 686 kcal/mol.
ATP Hydrolysis: ∆G = -7.3 kcal/mol.
Energy Extraction:
Through glucose oxidation, which proceeds through two phases: Glycolysis and Cellular Respiration.
Glucose Oxidation Phases
Phase 1: Glycolysis:
Location: Cytoplasm.
Converts glucose to pyruvate.
Phase 2: Cellular Respiration (CR):
Location: Mitochondria.
Divided into three stages: Oxidation of pyruvate, Citric Acid Cycle (Krebs Cycle), Electron Transport Chain.