Insulin Preparations

Insulin Preparations

1. Soluble (Regular) Insulin

• Only preparation suitable for intravenous use.

• Administered in diabetic emergencies.

• Given subcutaneously before meals for chronic management.

2. Formulations of Human Insulins

• Available in various ratios of short-acting and longer-lasting forms (e.g., 30:70).

• Commonly used twice daily.

• Some marketed in prefilled injection devices ('pens') for patient convenience.

3. Administration Details

• Small doses of soluble insulin control hyperglycemia post-injection.

• Risk of hypoglycemia in early morning hours.

• For a two-dose regimen :

  • Two-thirds of daily dose before breakfast.

  • One-third before evening meal.

• If patient engages in strenuous work, morning dose is reduced to prevent exercise-induced hypoglycemia.