otra vez
lecture 1 - blurting method
propeties and strucutre of memb rane - there are phrohlipdis and the fuck ass glycerides that are abunant and there are many types of phoshyolipids but choelstorl is notone of htem idl
prhoatyl glyceride includes the cholien group, he serine gorup, ehtanol, and linositol
the choline, serine, ethanol,a nd losontil, ethanol and lonsil linosutol. linositol. linositol.
lipids include, the spomyeling ,glcyolipid, choline, liostol, ethanol, serine, but not he cholestrol
properites of the membrane - ohorskuoud itgabuzautib us vased on ghdrpiobi and amipathinc interactison the tails structurfe matters, the hydrophobi vander wall. the cholesotryl is amipathi cbc of hte OH group.
serine will be fliped by flipase and the amcrophage fucks hem up , higer temp the tsruture of the lipds ovbilit, etc
okie so the frap line will tell u how fast it recovers, so a mjore steerp curve wshows faster recovy of the rptoeisn in the area after they hav ebeen quenched,
emembrane associated proteins. there is the plams amene transmmebrane,k anchor , peripheral
anchor is done through prenylation by adding a prenyl group to the protein throuh the caax moticfv.e involved playera re the prenyl tranferase, the protease caax and the ethyl trancferase.
many tranmembrean eproteiuns cros s the bilayer with a shoot a helical domain
,.,
tranembrea ne proteins will cross through with short a helical domains lolollol and htese domain are the tramembran. rprians that area a helical
some anchor proteins are attached throguh rpentyl on the c terminla or acylation through n termianl or gi anhcor c.
for prneylation it is the cystein and for aceytlation is it sthe glucine .
for prenylin it is the glycine and for acylation it is the glycin GLYCIN. GLYCI GLYhcin
ag ag ag ag
ag like
acretyl and glycin a like apples eat
acylation is for a a is for apple apples are eaten by gators. a is for acylation a i sof rpapple and apples are eaten byt gatos, again acylation is fo rht en terminsu and it is the palmatite acyl grop or he myristate mysterious muristate at the glycien groups cuz apples are eaten by gatos
the alipathic caax is the alla laue or val and the rest is andom is can b gaax or caax
sinlging mjoclules cna be roteisn pepdies amio acidxs neucleotide sterot
there are four types of main singal suivcal die cellprlideriaon and idfferneitation
ncuela refpcter super familu
homron erecpots
and cell sruface repsitrs and trnamemrbna ent he toher ones are intraceleualr
nfkb connection goes - ligan recptor - then the traf6, e3ligase, tac 1 and then theikkk ikk to ikb then the amcjhineray ligase tthen the 20s proteiase