respiratory
RESPIRATORY SYSTEM
COMPLETE STUDY GUIDE
Upper & Lower Anatomy · Physiology · Disorders · Clinical Care
Upper Anatomy Lower Anatomy Physiology Disorders Patient Care
LEARNING TARGETS
Know these before your quiz
UPPER RESPIRATORY TARGETS LOWER RESPIRATORY TARGETS
FOUNDATIONAL UNDERSTANDING
FOUNDATIONAL UNDERSTANDING
■ I can identify the structures of the upper respiratory system (nose, sinuses, pharynx, larynx).
■ I can identify the structures of the lower respiratory system (trachea, bron
■ I can explain the function of the upper respiratory system in protecting and filtering air.
■ I can explain how gas exchange occurs in the alveoli.
PATHOLOGY & BODY RESPONSE
PATHOLOGY & BODY RESPONSE
■ I can describe what is happening in the body during: cold, flu, sinusitis, pharyngitis, laryngitis, tonsillitis.
■ I can describe what is happening in the body during: pneumonia, asthma
■ I can compare viral vs. bacterial infections and how they affect the body differently.
■ I can explain how these disorders impair oxygen exchange.
■ I can recognize common signs and symptoms of upper respiratory illnesses.
■ I can recognize signs of respiratory distress: shortness of breath, wheezi
PATIENT CARE & CLINICAL THINKING
PATIENT CARE & CLINICAL THINKING
■ I can explain appropriate patient care interventions for upper respiratory conditions.
■ I can identify appropriate patient care interventions (oxygen therapy, inha
■ I can differentiate when antibiotics are appropriate versus when they are not.
■ I can analyze patient scenarios to determine severity of a respiratory con
■ I can apply knowledge to patient scenarios and determine appropriate care strategies.
■ I can explain the role of bronchodilators, steroids, and antibiotics.
PREVENTION & HEALTH PROMOTION
PREVENTION & HEALTH PROMOTION
■ I can identify prevention strategies such as hand hygiene and avoiding exposure.
■ I can identify prevention strategies including vaccines, smoking cessation
■ I can explain how lifestyle choices impact respiratory health.
■ I can explain the long-term impact of smoking and environmental exposu
SECTION 1 · UPPER RESPIRATORY ANATOMY
Overview
The upper respiratory system filters, warms, and humidifies incoming air and protects the body from airborne irritants before
air reaches the lungs. It includes: nasal cavities · paranasal sinuses · pharynx · larynx · trachea.
Respiratory System Study Guide · Page 1Nasal Septum Divides the nose into 2 nostrils via cartilage and bone.
Mucosa Lining Lines cavity walls — warms & humidifies air, traps foreign particles.
Cilia Hair-like cells that sweep trapped debris toward the throat for digestion.
Conchae 3 bony ridges (superior/middle/inferior) that increase surface area and create air
turbulence — traps more particles before they reach the lungs.
Hard & Soft Palate Hard palate = bone; soft palate = muscle. Separates nasal cavity from mouth.
Uvula Hangs from soft palate; prevents food from entering nasal cavity during swallowing.
Paranasal Sinuses
Location Air-filled spaces surrounding and draining into the nasal cavity (frontal, sphenoid, ethmoid,
maxillary).
Functions 1. Lighten the skull 2. Resonate speech 3. Produce mucus
Rhinitis Inflammation of sinus spaces. Caused by allergens or respiratory viruses. Symptoms:
runny nose, congestion, sneezing.
Pharynx (Throat)
Definition Shared passageway for both the respiratory AND digestive systems.
Nasopharynx Nasal portion — located behind nasal cavity. Contains pharyngeal tonsil (adenoid).
Oropharynx Oral (mouth) portion. Contains 2 palatine tonsils.
Laryngopharynx Lowest section — opens into larynx & esophagus. Contains epiglottis.
Tonsils (5 total) Pharyngeal/adenoid (1) + Palatine (2) + Lingual (2). Lymphatic tissue that traps & destroys
pathogens.
Larynx (Voice Box)
Description Short section of cartilage (9 pieces total) connecting pharynx to trachea.
3 Functions 1. Provide open airway (cartilage) sound (vocal cords)
2. Divert food to esophagus (epiglottis) 3. Produce
Thyroid Cartilage Largest cartilage — forms the Adam's apple.
Cricoid Cartilage Ring-shaped cartilage below thyroid — attaches larynx to trachea.
Hyaline Cartilage Keeps soft tissue of upper airway from collapsing during breathing.
Epiglottis Flap of elastic cartilage. Breathing: open — air passes freely. Swallowing: tips down to
cover larynx, directing food to esophagus.
Vocal Cords Volume = more air pushed through. Pitch = tension/thickness of cords. Articulation =
tongue, lips, teeth.
Vestibular Folds Beyond vocal cords — help close larynx to prevent food from entering respiratory system.
Nasal Cavity
Respiratory System Study Guide · Page 2Structure Rigid tube ~5 inches long. Reinforced by horseshoe-shaped cartilaginous rings (open
posteriorly).
Ring function Rings prevent tracheal collapse; flexible tissue between rings maintains neck flexibility.
Posterior surface Open rings connect to the esophagus, allowing it to expand when food passes.
Mucous membranes Trap dust/particles — cilia move them up to pharynx to be swallowed.
Trachea (Windpipe)
SECTION 2 · LOWER RESPIRATORY ANATOMY
Structures of the Lower Respiratory Tract
Bronchi Trachea splits (behind heart) into 2 primary bronchi — right and left, one entering each
lung. Continue branching: primary → secondary → tertiary.
Bronchioles Smaller tubes branching from bronchi. No cartilage — smooth muscle only. Lead to alveoli.
Alveoli Tiny grape-like air sacs at end of bronchioles. Site of gas exchange. Each surrounded by
capillary beds. ~300 million per lung.
Surfactant Secreted by Type II alveolar cells. Mixture of phospholipids & lipoproteins. Prevents
alveoli from collapsing by reducing surface tension.
Respiratory Zone Alveoli + surrounding capillaries = site of gas exchange. Distinguished from conducting
zone (trachea → bronchioles) which only moves air.
Respiratory Membrane Thin barrier (~0.5 µm) between alveolar air and capillary blood. O2 diffuses in; CO2
diffuses out.
Alveolar Macrophages Immune cells patrolling inside alveoli — engulf bacteria and particles.
The Lungs
Right Lung 3 lobes: superior, middle, inferior.
Left Lung 2 lobes: superior, inferior + cardiac notch (indentation to accommodate the heart).
Pleura Double-layer membrane. Visceral pleura = covers lung. Parietal pleura = lines thoracic
cavity.
Pleural Space Space between the two pleural layers filled with pleural fluid — reduces friction so lungs
slide smoothly during breathing.
Apex / Base Apex = narrow top. Base = broad bottom, resting on diaphragm.
SECTION 3 · PHYSIOLOGY & BREATHING
Mechanics of Breathing
Phase What Happens Key Note
Inhalation (Inspiration) Diaphragm + external intercostals CONTRACT → rib
cage expands → chest volume ↑ → pressure ↓ → air
rushes IN.
ACTIVE — requires muscle effort.
Respiratory System Study Guide · Page 3Exhalation (Expiration) Diaphragm + intercostals RELAX → rib cage recoils →
chest volume ↓ → pressure ↑ → air flows OUT.
PASSIVE at rest; forced exhalation
(coughing, singing) uses abdominal
muscles.
Lung Volumes
Tidal Volume (TV) Air exchanged with each normal resting breath (~500 mL).
Inspiratory Reserve Volume (IRV) Additional air that can be inhaled beyond a normal tidal breath.
Expiratory Reserve Volume (ERV) Additional air that can be exhaled beyond normal exhalation.
Residual Volume (RV) Air remaining in lungs after a maximum forced exhalation — keeps alveoli from collapsing.
Vital Capacity (VC) Maximum air consciously exchanged: TV + IRV + ERV.
Total Lung Capacity (TLC) Vital Capacity + Residual Volume ≈ 6 liters (adult men); ~10% less for adult females.
Type Where It Occurs What Moves
External Respiration Between alveoli and pulmonary capillary blood (in the
lungs).
O2 enters blood; CO2 enters alveoli to be
exhaled.
Internal Respiration Between systemic capillary blood and body tissues
(throughout body).
O2 delivered to cells; CO2 picked up and
returned to lungs.
Ventilation The mechanical process of breathing (moving air in and
out).
Precedes external respiration.
Respiratory Control
Primary Control Centers Medulla oblongata (VRG + DRG) and pons of the brainstem.
VRG — Ventral Respiratory Group Controls neurons for quiet, regular breathing rhythm. Primary pacemaker.
DRG — Dorsal Respiratory Group Collects sensory input from chemoreceptors and stretch receptors → relays to VRG.
Pons Centers Modify timing and smooth out breathing by communicating with VRG.
Most Important Stimulus CO2 level — rising CO2 → more carbonic acid → lower blood pH → chemoreceptors in
aorta & carotid artery signal medulla → increased breathing rate.
Physical Factors Talking, coughing, exercise, body temperature. Stretch receptors prevent overinflation.
Conscious Control Voluntary breathing is possible but limited — brainstem overrides when CO2/O2 reach
extreme levels.
Emotional Factors Gasping when scared, rapid breathing from stress, sighing.
Gas Exchange: External vs. Internal Respiration
SECTION 4 · UPPER RESPIRATORY DISORDERS
Respiratory System Study Guide · Page 4Common Cold — (Rhinovirus)
Pathology Viral infection of upper airways by rhinovirus.
Body Response Sneezing, congestion, runny nose, sore throat, low-grade fever.
Patient Care Rest, fluids, OTC symptom relief.
Prevention Hand hygiene, avoid touching face.
Tx Note NO antibiotics — viral infection.
Influenza — (Flu)
Pathology Influenza virus A, B, or C. More severe than cold.
Onset SUDDEN (within hours) — distinguishes it from cold (gradual, days).
Body Response High fever, muscle aches, headache, fatigue, cough, runny nose.
Treatment Antiviral medications effective if taken within 48 hours of onset.
Extra Notes Children more likely to get fever with cold than adults. Flu can cause ear infections.
Sinusitis
Pathology Inflammation of paranasal sinus cavities.
Body Response Facial pressure/pain, headache, nasal discharge, congestion.
Patient Care Hydration, nasal irrigation, decongestants.
Prevention Avoid allergens, treat colds early.
Treatment Decongestants. Antibiotics ONLY if bacterial.
Pharyngitis
Pathology Throat (pharynx) inflammation — viral or bacterial.
Body Response Sore throat, redness, difficulty swallowing.
Patient Care Warm fluids, lozenges, OTC pain relief.
Treatment Antibiotics ONLY for bacterial strep — prevents rheumatic fever.
Prevention Avoid infected individuals, hand washing.
Laryngitis
Pathology Inflammation of the larynx, usually viral.
Body Response Hoarseness, voice loss.
Patient Care Voice rest, hydration.
Prevention Avoid smoking and irritants.
Treatment Treat underlying cause (antibiotics if bacterial).
Respiratory System Study Guide · Page 5Tonsillitis
Pathology Body Response Patient Care Prevention Treatment Inflammation of the tonsils — viral or bacterial.
Sore throat, swollen lymph glands, fever.
Warm fluids, pain relief.
Hand washing, avoid infected contact.
Antibiotics if bacterial. Tonsillectomy if chronic/recurrent.
Cold vs. Flu — Quick Comparison
Feature Cold Flu
Cause Various viruses (mainly rhinoviruses) Influenza A, B, or C
Onset Gradual — over several days Sudden — within hours
Fever Rare in adults; possible in children Common, often high
Body Aches Mild Severe
Fatigue Mild Severe
Treatment Symptom management only (no Rx) Antivirals within 48 hours
Antibiotics? No (viral) No (viral — antivirals only)
Prevention Hand hygiene Annual flu vaccine
■ KEY RULE: Antibiotics ONLY work on bacteria. NEVER prescribe for viral infections (cold, flu). Antibiotic use for viral illness
contributes to antibiotic resistance and provides no benefit to the patient.
SECTION 5 · LOWER RESPIRATORY DISORDERS
Pneumonia
Pathology Body Response Patient Care Prevention Key Fact Infection (bacterial, viral, or fungal) inflames alveoli; alveoli fill with fluid or pus.
Impaired gas exchange → shortness of breath, fever, productive cough, decreased O2.
Antibiotics (if bacterial), monitor O2 levels, deep breathing exercises, hydration.
Pneumococcal vaccine, annual flu vaccine, hand hygiene.
Most common bacterial cause: Streptococcus pneumoniae.
Respiratory System Study Guide · Page 6Chronic Bronchitis
Pathology Chronic inflammation of bronchi; excess mucus production blocks airflow.
Definition Productive cough ≥3 months/year for ≥2 consecutive years.
Body Response Chronic cough with mucus, decreased O2, possible cyanosis.
Patient Care Smoking cessation, inhalers (bronchodilators), O2 therapy, pulmonary rehab.
Prevention Avoid smoking, wear mask in polluted environments, annual flu shots.
Asthma
Pathology Chronic inflammation + reversible narrowing of airways; triggered by allergens, cold air, exercise.
During Attack Bronchospasm (smooth muscle tightens) + mucosal swelling + mucus buildup → wheezing, chest
tightness.
Patient Care Rescue inhaler (bronchodilator — albuterol) for acute attack. Maintenance inhaler (corticosteroid)
long-term.
Monitoring Peak flow meter tracks airway obstruction over time.
Prevention Identify/avoid triggers, prescribed inhalers, stay vaccinated.
COPD
Definition Chronic Obstructive Pulmonary Disease — progressive combination of chronic bronchitis +
emphysema.
Emphysema Alveolar walls destroyed → loss of elasticity → air trapping → barrel chest, difficulty exhaling.
Body Response Coughing, fatigue, breathlessness, cyanosis.
Primary Cause Smoking (#1 risk factor).
Patient Care Smoking cessation, bronchodilators, steroids, O2 therapy, small meals, pulmonary rehab.
Prevention Avoid smoking, use protective gear, flu and pneumonia vaccines.
Tuberculosis (TB)
Pathology Bacterial infection — Mycobacterium tuberculosis — primarily in lungs. Airborne transmission.
Body Response Granulomas (tubercles) form to wall off bacteria. Symptoms: chronic cough, night sweats, weight
loss, fever.
Patient Care Long-term multi-drug antibiotics (6–9 months), isolation, monitor liver function.
Prevention BCG vaccine, high-risk screening, proper ventilation, masks.
Transmission Airborne droplets from coughing, sneezing, spitting.
✓ ALL lower respiratory disorders impair oxygen exchange in some way. Early detection and management dramatically improve
patient outcomes. Prevention: vaccines + smoking cessation + reducing environmental exposures.
SECTION 6 · CLINICAL CARE & PREVENTION SUMMARY
Respiratory System Study Guide · Page 7Condition Antibiotics? Instead / Note
Bacterial Pneumonia YES — antibiotics Core treatment
Strep Pharyngitis (strep throat) YES — antibiotics Prevents rheumatic fever
Bacterial Sinusitis YES — antibiotics Only if confirmed bacterial
Tonsillitis (bacterial) YES — antibiotics Tonsillectomy if chronic
Tuberculosis YES — multi-drug
antibiotics
6–9 months, liver monitoring
Common Cold NO — viral Symptom management only
Influenza (Flu) NO — viral Antivirals (e.g., Tamiflu) within 48 hrs
Viral Sinusitis NO — viral Decongestants + hydration
Laryngitis (viral) NO — viral Voice rest, hydration
Asthma NO — inflammatory Bronchodilators + steroids
COPD NO (unless infection) Bronchodilators, O2 therapy
Bronchodilators Relax smooth muscle around airways → widen bronchi/bronchioles. Used in asthma
(rescue inhaler: albuterol) and COPD.
Corticosteroids (Inhaled) Reduce long-term airway inflammation. Maintenance inhalers for asthma/COPD. NOT for
acute attacks.
Oxygen Therapy Given when SpO2 drops to dangerous levels. Common in severe COPD exacerbations
and pneumonia.
Peak Flow Monitoring Handheld device measuring max exhalation speed. Used in asthma to monitor control.
Green/yellow/red zones guide medication decisions.
Pulmonary Rehabilitation Structured program: exercise, breathing techniques, education. Improves quality of life in
COPD patients.
Antivirals For influenza — must be given within 48 hours of symptom onset. Example: oseltamivir
(Tamiflu).
When to Use Antibiotics — Decision Guide
Key Medications & Interventions
Prevention Strategies by Condition
Condition Behavioral Prevention Vaccine / Medical Prevention
Common Cold / Flu Hand hygiene, avoid sick contacts Annual flu vaccine
Pneumonia Hand hygiene, avoid sick contacts Pneumococcal vaccine + flu vaccine
Tuberculosis Ventilation, N95 mask, high-risk screening BCG vaccine
Asthma Identify and avoid allergens/triggers Prescribed maintenance inhaler
COPD / Bronchitis Smoking cessation, protective gear, clean air Flu + pneumonia vaccines
Tonsillitis / Pharyngitis Hand washing, avoid infected people Complete antibiotic course if bacterial
Respiratory System Study Guide · Page 8Cyanosis Bluish discoloration of skin/lips/fingernails. Indicates critically low blood oxygen. Medical
emergency.
Wheezing High-pitched whistling sound during breathing. Indicates airway narrowing (asthma,
COPD).
Shortness of Breath Difficulty breathing; reduced air movement. Can indicate pneumonia, asthma, COPD, TB.
Productive Cough Cough that produces mucus/sputum. Key feature of chronic bronchitis, pneumonia, TB.
Night Sweats Drenching sweats during sleep. Classic sign of tuberculosis.
Barrel Chest Rounded, enlarged chest from air trapping. Sign of advanced emphysema/COPD.
Signs of Respiratory Distress — Know These
SECTION 7 · MASTER VOCABULARY
Respiratory System Study Guide · Page 9Nasal Septum Cartilage/bone wall dividing the nose into 2 nostrils.
Respiratory Membrane Thin barrier (~0.5 µm) between alveolar air and
capillary blood.
Mucosa Lining Moist membrane lining nasal cavity; warms air,
traps particles.
Pleura Double membrane covering lungs and lining
thoracic cavity.
Conchae 3 bony nasal ridges increasing surface area and air
turbulence.
Pleural Fluid Lubricating fluid in pleural space; reduces friction
during breathing.
Paranasal Sinuses Air spaces around nasal cavity; lighten skull,
resonate speech, produce mucus.
Cardiac Notch Indentation in left lung accommodating the heart.
Rhinitis Inflammation of nasal/sinus lining; caused by
allergens or viruses.
Diaphragm Primary breathing muscle; contracts = inhalation.
Tidal Volume Air exchanged per normal resting breath (~500 mL).
Uvula Fleshy flap on soft palate; prevents food entering
nasal cavity during swallowing.
Residual Volume Air remaining after maximum exhalation; prevents
lung collapse.
Pharynx The throat; shared by respiratory and digestive
systems.
Vital Capacity Maximum air consciously moved: TV + IRV + ERV.
Nasopharynx Nasal section of pharynx; contains pharyngeal
tonsil (adenoid).
Total Lung Vital capacity + residual volume (~6L men, ~10%
less women).
Oropharynx Oral section of pharynx; contains palatine tonsils.
External Respiration Gas exchange between alveoli and pulmonary
blood in the lungs.
Laryngopharynx Lowest pharynx section; contains epiglottis, opens
to larynx + esophagus.
Internal Respiration Gas exchange between blood and body tissues
throughout the body.
Larynx Voice box; connects pharynx to trachea; 3
functions: open airway, divert food, sound.
VRG Ventral Respiratory Group; pacemaker for quiet,
regular breathing.
Epiglottis Elastic cartilage flap; covers larynx during
swallowing to prevent aspiration.
DRG Dorsal Respiratory Group; collects sensory input,
relays to VRG.
Thyroid Cartilage Largest laryngeal cartilage; forms the Adam's
apple.
Chemoreceptors Sensors in aorta/carotid artery detecting CO2 and
O2 levels.
Cricoid Cartilage Hyaline Cartilage Ring-shaped cartilage attaching larynx to trachea.
Structural cartilage keeping larynx and trachea from
collapsing.
Bronchodilator Medication relaxing airway smooth muscle; widens
bronchi.
Cyanosis Blue skin/lips from critically low blood oxygen.
Vocal Cords Elastic tissue folds in larynx that vibrate to produce
sound.
Surfactant Prevents alveoli from sticking shut; deficient in
premature infants.
Trachea Windpipe; ~5 inch rigid tube with horseshoe
cartilage rings to bronchi.
Granuloma Immune cell cluster walling off infection (TB
tubercles).
Bronchi Two large tubes (R+L) branching from trachea into
each lung.
BCG Vaccine Bacille Calmette-Guérin; protects against
tuberculosis.
Bronchioles Small tubes branching from bronchi; lead to alveoli.
Alveolar Macrophage Immune cell engulfing bacteria and particles inside
Alveoli Microscopic air sacs where O2/CO2 gas exchange
occurs.
alveoli.
Surfactant Phospholipid/lipoprotein mix preventing alveolar
collapse.
Pulmonary Structured program improving function in chronic
lung disease.
Respiratory Zone Alveoli + capillaries; actual site of gas exchange.
Peak Flow Monitoring Measures max exhalation speed; tracks asthma
control.
Capacity Rehab SECTION 8 · QUICK-REFERENCE COMPARISON TABLES
Upper Respiratory Disorders at a Glance
Disorder Cause Key Symptoms Treatment
Common Cold Rhinovirus Congestion, sneezing, mild sore throat Rest/fluids; NO antibiotics
Influenza Influenza A/B/C Sudden fever, body aches, fatigue,
cough
Antivirals within 48 hrs; vaccine
Sinusitis Viral or bacterial Facial pressure, headache, discharge Decongestants; antibiotics if bacterial
Respiratory System Study Guide · Page 10Pharyngitis Viral or bacterial
(strep)
Sore throat, redness Antibiotics if strep
Laryngitis Viral (usually) Hoarseness, voice loss Voice rest, hydration
Tonsillitis Viral or bacterial Sore throat, swollen glands Antibiotics if bacterial; tonsillectomy if
chronic
Disorder Main Cause Key Body Changes + Symptoms Treatment / Prevention
Pneumonia Bacteria/virus/fungus Fever, cough, SOB, low O2; alveoli fill with
fluid/pus
Antibiotics (if bacterial), O2,
hydration; vaccines prevent
Chronic Bronchitis Smoking (mainly) Productive cough 3+ months/yr, mucus, cyanosis Smoking cessation, inhalers, O2,
pulm rehab
Asthma Allergens/irritants Wheezing, chest tightness, bronchospasm Rescue inhaler; avoid triggers;
maintenance inhaler
COPD Smoking (#1) SOB, fatigue, air trapping, cyanosis Stop smoking, bronchodilators,
steroids, O2
Tuberculosis M. tuberculosis
(airborne)
Chronic cough, night sweats, weight loss, fever Multi-drug antibiotics 6-9 months,
isolation; BCG vaccine
1. The 3 sections of the pharynx: nasopharynx, oropharynx, laryngopharynx
2. The 3 functions of the larynx: open airway, divert food, produce sound
3. Epiglottis: OPEN during breathing, CLOSES during swallowing
4. Trachea rings: horseshoe-shaped, open posteriorly (connects to esophagus)
5. Gas exchange happens in the alveoli (respiratory zone)
6. Surfactant prevents alveoli from collapsing
7. Inhalation = ACTIVE (muscle contraction); Normal exhalation = PASSIVE (muscle relaxation)
8. Most important breathing stimulus = CO2 level (not O2)
9. Antibiotics for BACTERIA only — NEVER for viral infections
10. COPD = chronic bronchitis + emphysema; #1 cause = smoking
11. TB symptoms: chronic cough + night sweats + weight loss + fever
12. Cyanosis = medical emergency = critically low O2
13. Rescue inhaler (bronchodilator) for acute asthma; maintenance inhaler for long-term control
14. Right lung = 3 lobes; Left lung = 2 lobes + cardiac notch
15. Cold = gradual onset; Flu = SUDDEN onset within hours
Rescue Inhaler: Albuterol
Type: Short‑acting bronchodilator (SABA)
Where it works:
Bronchi + bronchioles (the small tubes that carry air into the lungs)
How it works in the body:
●
●
●
●
Albuterol attaches to beta‑2 receptors on the smooth muscles of the bronchioles.
This causes the muscles to relax immediately.
Relaxation = airways open wider → more oxygen can move in and out.
Works in 1–5 minutes and lasts 3–4 hours.
Why it’s used:
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●
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Asthma attacks
Sudden shortness of breath
Wheezing
Exercise‑induced bronchospasm
Helpful Tip
Albuterol is like a “quick‑release button” that instantly opens tight airways.
2. Maintenance Inhaler: Fluticasone
Type: Inhaled corticosteroid (ICS)
Where it works:
Bronchi + bronchioles (lining of the airway)
How it works in the body:
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●
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Fluticasone reduces inflammation inside the airway walls.
Less inflammation =
○
Less swelling
○
Less mucus
○
Fewer flare‑ups
Works slowly — takes days to weeks to reach full effect.Why it’s used:
●
●
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Long‑term asthma control
Prevents symptoms from happening
Reduces airway sensitivity
Helpful Tip
Fluticasone is like a daily lotion for the airways — it keeps them calm and prevents irritation.
3. Maintenance Inhaler: Symbicort
Type: Combination inhaler
●
●
Budesonide (steroid → reduces inflammation)
Formoterol (long‑acting bronchodilator → keeps airways open)
Where it works:
Bronchi + bronchioles
How it works in the body:
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●
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Budesonide reduces swelling and mucus over time.
Formoterol relaxes airway muscles for 12 hours.
Together they:
○
Prevent asthma attacks
○
Improve daily breathing
○
Reduce emergency inhaler use
Why it’s used:
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Moderate to severe asthma
COPD
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Students should know: NOT for sudden attacks
Helpful tip
Symbicort is like a security system:
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One part reduces inflammation
One part keeps the airways open all day4. Bronchodilator: Levalbuterol
Type: Short‑acting bronchodilator (similar to albuterol)
Where it works:
Bronchi + bronchioles
How it works in the body:
●
●
●
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Targets beta‑2 receptors like albuterol
Relaxes airway muscles
Opens airways quickly
Often causes fewer side effects (less jitteriness)
Why it’s used:
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●
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Asthma attacks
COPD flare‑ups
Patients sensitive to albuterol side effe