Etiology and Pathophysiology
Caused by infectious organisms (bacteria, parasites, viruses).
A healthy colon features short-chain fatty acids and beneficial bacteria aiding digestion.
Antibiotics disrupt normal flora, increasing infection susceptibility.
Risk Factors
Immunocompromised individuals.
Tube feedings.
Certain medications.
Food intolerances.
Laxative use.
Underlying diseases.
Clinical Manifestations
Upper GI Infection: Large volume of watery stools, cramping, periumbilical pain, low-grade or normal temperature, nausea and vomiting before diarrhea.
Lower GI Infection: Fever, bloody diarrhea, small, frequent stool amounts.
Severe Diarrhea: Life-threatening dehydration, electrolyte disturbances, acid-base imbalance.
Diagnostics
Stool cultures for severe cases with fever or bloody stool.
Stool specimen exam for blood, mucus, WBCs.
Multi-pathogen tests for viral, bacterial, or parasitic causes.
Lab tests (CBC, BUN, Creatinine).
Chronic diarrhea tests for electrolyte, pH, osmolality, fat, and undigested muscle fiber.
Interprofessional Care
Management depends on severity/cause:
Acute Care: Prevent transmission, replace fluids/electrolytes, protect skin.
Severe Cases: IV fluids/electrolytes/vitamins, total parenteral nutrition (TPN).
Avoid trigger foods/medications; psyllium fiber may help thicken stool; short-term anti-diarrheal medications (not for infectious diarrhea); antibiotics for severely ill/immunocompromised.
Overview
A highly hazardous healthcare-associated infection (HAI).
Risk Factors
Antimicrobial use, chemotherapy, immunosuppressants.
ICU stay, prolonged hospitalization, recent surgeries, acid-suppressing medications.
Prevention & Treatment
Spores survive up to 70 days on surfaces.
Handwashing with soap/water is essential (not alcohol-based rubs).
Use of contact isolation (gown and gloves).
Clean surfaces with 10% bleach wipes.
Treatment options: Oral vancomycin, fidaxomicin, metronidazole, and fecal microbial transplant (FMT) for recurrent cases.
Etiology and Pathophysiology
Motor Function Issues: Impaired rectal sphincter or weak rectal floor muscles (due to trauma/surgery).
Sensory Function Issues: Inability to sense need for defecation (related to stroke, MS, spinal injury).
Fecal Impaction: Hardened feces causing liquid stool to seep around; treatment includes digital de-impaction or cleansing enema.
Diagnostics & Care
Health history, physical exam, abdominal imaging (X-ray, CT scan, colonoscopy).
Treatment focuses on identifying/addressing causes and dietary adjustments (fiber, fluids).
Options include anti-diarrheal medications, Kegels, biofeedback therapy, electrostimulation, Solesta gel injection, and possibly surgery.
Nursing management: Bowel training, frequent toileting, skin care with barrier creams.
Etiology and Pathophysiology
Hard, dry stools; difficulty passing.
Common causes: Low fiber intake, dehydration, inactivity, voluntary stool withholding, certain medications (e.g., opioids).
Overuse of laxatives may lead to cathartic colon syndrome.
Clinical Manifestations
Abdominal discomfort, bloating, rectal pressure.
Complications like hemorrhoids (from straining), obstructive bowel movement, fecal impaction.
Diagnostics & Care
Diagnosed via history, physical exams, imaging (X-ray, colonoscopy).
Treatment strategies include dietary fiber increase, hydration, exercise, possible laxatives.
Nursing management: Encourage bowel regularity, proper positioning during defecation, privacy.
Etiology & Causes
Sudden onset requiring urgent attention; possible causes include gynecologic conditions, infections, vascular issues, obstructions, and trauma.
Potential complications: peritonitis, shock (hypovolemic, septic).
Clinical Manifestations & Diagnostics
Symptoms may include nausea, vomiting, diarrhea, constipation, fever, bloating, rebound tenderness.
Diagnostics include CBC, urinalysis, imaging (X-ray, CT, ultrasound), ECG and pregnancy tests.
Interprofessional Care
Emergency management: Identify cause, monitor complications, manage pain.
Possible emergency surgery, with pre-op management being NPO and Hibiclens bath; post-op care includes treating nausea/vomiting, early ambulation, and monitoring.
Definition & Pathophysiology
Characterized by chronic abdominal pain and altered bowel patterns (diarrhea/constipation).
Linked to psychological stressors, GI infections, food intolerances.
Clinical Manifestations
Abdominal pain at least 1 day/week for 3 months.
Symptoms include bloating, nausea, flatulence, urgency, mucus in stool, fatigue, sleep issues.
Diagnostics & Care
Based on symptom history.
Treatment: Stress management, dietary changes (low FODMAP diet), medications as needed, and keeping a symptom diary.
Etiology and Pathophysiology
Inflammation of the appendix due to obstruction (fecalith).
Leads to venous engorgement and possibly gangrene, perforation, peritonitis.
Clinical Manifestations
Symptoms include dull periumbilical pain, anorexia, nausea, vomiting; pain shifts to right lower quadrant (RLQ).
Low-grade fever and signs like rebound tenderness, muscle guarding.
Diagnostics
Physical examination, laboratory tests (WBC, UA), CT scan preferred for imaging.
Nursing Management
Including hydration, pain management, and preventing complications:
NPO, antiemetics, monitoring vital signs, ongoing patient assessment, post-operative care (ambulation and dietary advancement).
Etiology and Pathophysiology
Inflammation of the peritoneum from primary or secondary causes (like appendicitis, trauma, or perforated viscus).
Clinical Manifestations
Abdominal pain, tenderness, rebound tenderness, muscular rigidity.
Symptoms include shallow breathing due to pain, distention, fever, elevated heart rate.
Diagnostics
Patient assessment, history, CBC, peritoneal aspiration if necessary. Imaging includes X-ray, CT, ultrasound.
Interprofessional Care
Conservative care for mild cases with IV fluids/antibiotics; surgical options for locating causes, draining purulent fluid, and repairing damage.
Overview
Chronic GI tract inflammation characterized by periods of remission and exacerbation. Includes Ulcerative Colitis (UC) and Crohn’s Disease (CD).
Etiology and Pathophysiology
Autoimmune reactions and environmental triggers, with genetic and immune function alterations.
Crohn's Disease: Can affect the entire GI tract; involves all bowel wall layers, leads to deep ulcers and obstructions.
Ulcerative Colitis: Limited to the colon, primarily affects mucosal layer with potential complications.
Clinical Manifestations
Both IBD conditions manifest as diarrhea, weight loss, abdominal pain, fever, and fatigue, with variations in stool features.
Diagnostics and Care
Aimed at ruling out other diseases with lab tests and imaging studies.
Treatment includes drug therapy (aminosalicylates, antimicrobials, corticosteroids) and surgical therapy.
Overview
Occurs when intestinal contents cannot pass through the GI tract. May be partial or complete, mechanical or non-mechanical.
Etiology and Causes
Mechanical obstructions often in the small intestine (adhesions, hernias, cancers), while non-mechanical are due to reduced peristalsis or neuromuscular issues.
Clinical Manifestations
4 hallmark signs: abdominal pain, vomiting, distention, and constipation.
Diagnostics
History, imaging (CT, X-ray), lab tests.
Interprofessional Care
Management based on severity, with non-surgical measures (NG tube, IV fluids) or surgical interventions (resection, colostomy).
Risk Factors
Family history, personal history of IBD or CRC, obesity, high red meat consumption, smoking.
Clinical Manifestations
Early signs like fatigue and weight loss; late signs show rectal bleeding, abdominal pain, changes in bowel habits.
Diagnostics
Colonoscopy for screenings and tissue biopsy starting at age 50 (earlier for high-risk individuals).
Treatment
Surgery (tumor resection), chemotherapy, radiation therapy, with palliative care as needed.
Overview
Diverticulosis: Non-inflamed diverticula.
Diverticulitis: Inflammation causing infection, potentially leading to perforation.
Causes & Risk Factors
Often arises from a low-fiber diet, with increased risk from obesity, smoking, and immunosuppression.
Clinical Manifestations
Mild symptoms include bloating; severe cases can have nausea, vomiting, and LLQ pain.
Diagnostics & Management
Imaging and dietary management with a high-fiber diet during the diverticulosis stage, bowel rest, and antibiotics for diverticulitis.
Hernias
Types include inguinal, umbilical, femoral, and ventral/incisional; management includes surgical repairs and observation for strangulation symptoms.
Celiac Disease
Autoimmune reaction to gluten; management involves a strict gluten-free diet.
Lactose Intolerance
Caused by a deficiency in lactase; symptoms managed with lactose-free diets and supplements.
Short Bowel Syndrome
Results from Crohn’s disease or surgical resection; management includes fluid and nutritional support.
Stoma Care
Emphasize pouch emptying when two-thirds full and hydration to prevent dehydration.
Client Education
Address emotional distress around body image, proper cleaning techniques, diet modifications for gas control, and recognizing stoma complications.
General Management
For diarrhea, prioritize hydration and electrolyte balance; teach dietary management.
For constipation, recommend fiber and hydration, along with monitoring for potential complications.
Clinical Practice Scenarios
Recognize the signs requiring more comprehensive evaluation and intervention for patients with gastrointestinal ailments.
These notes should serve as a comprehensive guide for lower GI problems, addressing key aspects needed for exam preparation and clinical understanding.