BIO142 timeline

DNA substance is in the nuclei

Miescher

1869

Chromosomes are made up of DNA and protein; nucleus basis of heredity Collaborative work

1887

Classical theories on inheritance published and then rediscovered

Mendel

1866, 1900

Nitrogenous bases make up DNA

Kossel

late 1800's

Genetic material and proteins are linked; faulty enzyme causes heritable disease (alkaptonuria)

Garrod

1908

Transformation principle; phenotypes can be transferred

Griffith

1928

A gene codes for a protein

Beadle and Tatum

1941

DNA is the agent that causes transformation

Avery, McLeod, and McCarty

1944

In DNA, amount of adenine=amount of thymine, and cytosine=guanine

Chargaff

1948

DNA is made up of polynucleotide chains

Todd

1951

DNA is the material that is passed down from parental virus to progeny viruses

Hershey and Chase

1952

Secondary structure of DNA

Watson and Crick

1953