CELL-TRANSPORT
Cell Transport Overview
Various types of transport processes occur across the cell membrane.
Simple Diffusion
Requires no energy.
Molecules move from an area of high concentration to an area of low concentration.
Diffusion
It is a passive process, meaning no external energy is used.
Molecules move spontaneously due to their natural kinetic energy.
Diffusion of Lipids
Process illustrated as:
(a) Dye is dropped into water.
(b) Diffusion begins, molecules start to distribute.
(c) Over time, dye molecules become evenly distributed among water molecules.
Diffusion Through a Membrane
High concentration on one side and low concentration on the other.
Solute moves down the concentration gradient (high to low).
Osmosis
Specifically refers to the diffusion of water across a membrane.
Water moves from areas of high water concentration to low water concentration.
Water is attracted to solutes; thus, it moves towards areas of higher solute concentration.
Direction of Water Movement
High Water Concentration: Water diffuses from higher to lower concentration.
Low Water Concentration: Water moves to areas with higher solute concentration.
Solutions and Cell Response
Isotonic Solution:
Solute concentration inside the cell is equal to that outside.
Water moves in and out at equal rates (equilibrium).
Hypotonic Solution:
Solute concentration outside the cell is lower than inside.
Water flows into the cell, causing it to swell.
Hypertonic Solution:
Solute concentration outside the cell is higher.
Water flows out, making the cell shrink.
Cellular Effects of Solutions
Cytolysis:
Occurs in hypotonic solutions; cells swell and burst.
Plasmolysis:
Occurs in hypertonic solutions; cells shrink and shrivel.
Osmosis in Red Blood Cells
Red blood cells exhibit different responses in isotonic, hypotonic, and hypertonic solutions.
Transport Mechanisms
Passive Transport
Simple Diffusion: Requires no energy; substances move from high to low concentration (e.g., oxygen, carbon dioxide).
Facilitated Diffusion: Uses transport proteins; molecules move from high to low concentration without energy (e.g., glucose).
Active Transport
Requires energy (ATP) to move substances against their concentration gradient (from low to high concentration).
Examples: Sodium-Potassium Pump; transports Na+ out and K+ in.
Types of Transport Proteins
Channel Proteins: Have pores for materials to cross.
Carrier Proteins: Change shape to transport materials across the membrane.
Endocytosis and Exocytosis
Exocytosis
A type of active transport moving substances out of the cell via vesicles that fuse with the plasma membrane.
Common in hormone secretion and cell communication.
Endocytosis
Divided into three forms:
Pinocytosis: Ingests extracellular fluid and dissolved substances.
Receptor-Mediated Endocytosis: Integral proteins recognize and take in specific molecules (e.g., hormones).
Phagocytosis: Engulfs large particles (e.g., bacteria) into vesicles.
Summary of Active Transport Types
Pinocytosis: Cell drinking (intake of fluids).
Phagocytosis: Cell eating (intake of larger particles).
Receptor-Mediated Endocytosis: Involves binding specific substances to receptors before uptake.