ch14- Plant Molecular Systematics
Plant Molecular Systematics Notes
Types of Molecular Data
DNA sequences
DNA restriction sites: RFLPs
Allozymes: different forms of proteins
Microsatellites: DNA regions with tandem repeats
RAPDs: Random Amplification of Polymorphic DNA
AFLPs: Amplified Fragment Length Polymorphism
Acquisition of Plant Molecular Data
Collect plant samples and prepare vouchers
Use live samples, e.g., allozyme analysis
Use dried or liquid-preserved samples for DNA analysis
DNA Sequence Data
Components:
Adenine (A), Guanine (G), Cytosine (C), Thymine (T)
Purines: A, G
Pyrimidines: C, T
PCR: Polymerase Chain Reaction
Definition: Amplifies DNA to produce thousands of copies
Process:
Isolate and purify DNA, heat to denature
Use primers: short, conserved DNA regions
Include Taq polymerase and nucleotides
DNA Sequencing
Method: Similar to PCR but uses dideoxynucleotides which terminate synthesis.
Output: Length of DNA strands determined by electrophoresis
DNA Sequence Types
Chloroplast DNA (cpDNA)
Nuclear DNA (nDNA)
Mitochondrial DNA (mtDNA): less used in plants, more in animals
Chloroplast Coding Genes
atpB: ATP synthesis
rbcL: Photosynthesis (RUBISCO)
matK: Splicing type II introns
ndhF: NADH dehydrogenase
Internal Transcribed Spacers (ITS)
ITS Region: Involves nrDNA, used in phylogenetic studies
ETS Region: External transcribed spacer for additional data
DNA Alignment
Compare nucleotide sequences across taxa for variability
Character coding for differences
Models of Molecular Evolution
Different base substitution models affecting phylogenetic analysis
Restriction Fragment Length Polymorphism (RFLP)
Definition: Variation in the length of DNA fragments after digestion with restriction enzymes
E.g., using EcoRI enzyme
Allozymes
Definition: Variants of enzymes
Historically used but rarely today due to complexity in coding for phylogenetic studies
Next Generation Sequencing (NGS)
Description: High Throughput Sequencing allows massive data generation
Advantages: More data, lower costs per base, can sequence transcriptomes
Disadvantages: Requires advanced computing power for data assembly
Microsatellites and RAPDs
Microsatellites: Tandem repeats indicating genetic differences
RAPDs: Variability due to randomly generated primers leading to different lengths in amplicons
AFLP Technique
Steps: DNA cleavage by restriction enzymes, amplification via PCR with primers and adapters.