Peds U2

High Risk Pregnancy

Multi-Fetal Pregnancy

  • Chorion:
    • Definition: The layer that connects the baby to the mother's blood supply.
    • Significance: Used to describe the placentas.
  • Dichorionic and Diamniotic:
    • Meaning: Two placentas and two amniotic sacs.
  • Monochorionic:
    • Definition: When twins share one placenta but have their own amniotic sacs.
    • Important: Monitor for twin-to-twin transfusion, where blood flow between the twins is uneven.
  • Twin Splitting:
    • Early Split:
    • Meaning: Each twin has their own placenta.
    • Terminology: Dichorionic; considered safest type of twin pregnancy.
    • Late Split:
    • Definition: Occurs days 4-8 post-conception; results in shared placenta but individual amniotic sacs.
    • After 13 Days:
    • Potential Outcome: Conjoint twins (Siamese twins).
  • Singleton Babies: Definition: One baby pregnancy.
  • Identical Twins:
    • Definition: Result from one fertilized egg splitting into two.
    • Genetic Makeup: Identical; can only be two boys or two girls.
    • Twin A vs Twin B:
    • Twin A: Closer to cervical opening.
    • Twin B: Furthest from cervical opening.
  • Fraternal Twins:
    • Combination: Can be two boys, two girls, or one of each.
    • Genetic Makeup: Different.

Multiple Gestation Risks

  • Increased Risk: Preterm delivery.
  • Therapeutic Management:
    • Approaches: Serial ultrasounds, close monitoring during labor, operative delivery.
  • Nursing Assessment:
    • Signs: Uterus larger than expected for estimated due date (EDB); confirmed via ultrasound.
  • Nursing Management:
    • Focus: Education & support antepartally; manage labor with perinatal team on standby; assess postpartum for hemorrhage risk.
    • Patient Management:
    • Bedrest admission may occur.
    • Vaginal delivery for one twin; C-section for others if needed.
    • Emergency C-section if both twins are in distress.
  • Monitoring Parameters:
    • Vital signs, signs of bleeding, skin color evaluation (for paleness), nausea, vomiting, dizziness.
    • Blood type collected.

Complications of Pregnancy

Premature Rupture of Membranes (PROM)
  • PROM:
    • Definition: Membranes rupture in women at 37 weeks or beyond.
  • PPROM:
    • Definition: Membranes rupture in women less than 37 weeks.
  • Treatment:
    • Dependent on gestational age.
    • Avoid unsterile digital cervical exams until active labor.
    • Expectant management if fetal lungs are immature.
  • Assessment Points:
    • Risk factors, signs and symptoms of labor, electronic fetal heart rate (FHR) monitoring, amniotic fluid characteristics.
  • Nitrazine Test:
    • Process: Testing vaginal fluid pH using test strips.
    • Interpretation: Blue indicates alkaline, suggesting membranes are ruptured.
  • Fern Test:
    • Process: Vaginal fluid placed on a slide under a microscope; will look like fern leaves if indicative of rupture.
  • Ultrasound:
    • Note: No sterile vaginal exams until labor starts.
  • Amniotic Fluid Characteristics:
    • Normal: Clear/yellowish.
    • Abnormal: Any color other than clear may indicate meconium-stained fluid.
    • Action Required: Respiratory standby due to potential risks involved.
  • Risks Associated with PROM:
    • Loss of protective seal leads to:
    • Risk for Infection
    • Risk for Cord Compression
    • Risk for Cord Prolapse
    • Emergency Protocol:
    • If cord felt during sterile vaginal exam (SVE) or visualized, initiate code for emergency C-section.
Management for PROM
  • Prevention of Infection.
  • Identify uterine contractions.
  • Discharging home with PPROM if no labor after 48 hours.

Group Beta Streptococcus (GBS)

  • Primary Cause of Neonatal Morbidity:
    • Not sexually transmitted.
    • Potential for neonatal sepsis risk if maternal tests positive.
  • Management for positive GBS:
    • Monitor maternal temperature.
    • Administer antibiotics (e.g., Penicillin or Ampicillin) during labor.
    • C-section Protocol: If the patient has a C-section, treatment may not be necessary.
Chlamydia
  • Association with PROM:
    • Risk of endometritis:
    • Symptoms: Inflammation of the uterine lining causing fever, lower abdominal pain, and abnormal vaginal bleeding (common postpartum).
Other Infections in Newborns
  • Conjunctivitis (in newborns):
    • Treatment: Zithromax or Amoxicillin.
  • Herpes:
    • Protocol: If client has active lesions, C-section is permitted.
    • Preventative Measure: Acyclovir is prescribed to prevent active lesions during delivery.

Adolescent Pregnancy Risks

  • Prevalence:
    • Higher incidence among Hispanic and African American teens.
  • Conditions of Concern:
    • Pre-eclampsia.
    • Iron Deficiency Anemia.
    • Preterm Labor.
    • Cephalopelvic Disproportion (CPD): Sometimes leads to C-section.

Education for Adolescents

  • Focus Areas:
    • Sexual education.
    • Oral contraceptive education.
    • Nutrition: Encourage five servings of fruits and vegetables daily.
    • Encourage early prenatal care and access to resources.
    • Support finishing high school.

Advanced Maternal Age (AMA)

  • Description:
    • Refers to pregnancies in women over 35.
  • Associated Risks:
    • Thromboembolic Problems (increased clotting).
    • Higher rates of fetal and neonatal mortality.
    • Risk of postpartum hemorrhage related to uterine atony.

Placental Issues

Placental Abruption
  • Definition:
    • Premature separation of the placenta from the uterine wall before birth.
  • Causes:
    • Hypertension, trauma, substance abuse.
  • Assessment Findings:
    • Abdomen Signs: Feels “board-like.”
    • Dark red vaginal bleeding.
  • Treatment Strategy:
    • Continuous FHR monitoring, vital signs assessment for hypovolemic shock, side lying positioning, oxygen administration, emergency C-section.
Placenta Previa
  • Definition:
    • Condition where the placenta abnormally implants in the lower segment of the uterus, near or over the cervical opening.
  • Causes:
    • Smoking, drug use, uterine scarring.
  • Assessment Findings:
    • Painless bright red bleeding; non-tender uterus.
  • Treatment Guidelines:
    • Avoid vaginal examinations, replace IV fluids, monitor bleeding, and no sexual intercourse.
Vasa Previa
  • Definition:
    • Risk of fetal blood loss due to velamentous insertion where the cord attaches to the membranes, leaving it unprotected.
  • Prevalence:
    • More common in multiple pregnancies.

Iron Deficiency Anemia

  • Description:
    • Common complication, associated with low birth weight.
  • PICA:
    • Craving for non-nutritive substances.

Iron Supplements

  • Possible Side Effects:
    • Cause constipation and dark stool.
  • Duration for replenishment:
    • Takes 4 months for iron levels to normalize.
  • Lab Tests Needed:
    • Hemoglobin & Hematocrit.

Sickle Cell Anemia

  • Description:
    • A recessively inherited hemolytic disease.
  • Monitoring Needs:
    • Monitor for intrauterine growth restriction (IUGR) and assess frequently for urinary tract infections (UTIs).
  • Emergency Response:
    • Sickle cell crisis can occur; ensure hydration and oxygenation.

Hyperemesis Gravidarum

  • Definition:
    • Severe form of nausea and vomiting in pregnancy; usually resolves by week 20.
  • Goals:
    • Limit weight loss to less than 5% of pre-pregnancy body weight.
  • Causes:
    • Can lead to dehydration, metabolic acidosis, alkalosis, and hypokalemia.
  • Assessment Needs:
    • Onset, duration, and characteristics of nausea/vomiting; monitor liver enzymes, CBC, BUN, electrolytes, and urine specific gravity.
    • Ultrasound:
    • Assess amniotic fluid levels.

Therapeutic Management

  • Involves:
    • Hospitalization, total parenteral nutrition (TPN).

Cardiac Disease in Pregnancy

Prenatal Management
  • Practice Guidelines:
    • Establish baseline status, and assess for changes frequently.
    • Emphasize rest and adequate nutrition.
    • Adjust cardiac medications as necessary, including anticoagulant therapy.
    • Infection control measures during labor and delivery.
  • Monitoring During Labor:
    • Monitor IV fluids; use Pitocin cautiously.
  • Postpartum Management:
    • Weekly weight monitoring, assess for hemorrhage, and apply antibiotic prophylaxis as needed.
Blood Incompatibility Conditions
  • ABO Incompatibility:
    • Type O mothers and fetuses with type A, B, or AB.
    • Less severe than Rh incompatibility.
  • Rh Incompatibility:
    • Overview: Exposure of an Rh-negative mother to Rh-positive fetal blood; sensitization causes antibody production, increasing risk with each subsequent pregnancy.
    • Fetus with Rh-positive blood is at risk.
    • Assessment Needs:
    • Determine maternal blood type and Rh status.
    • Management:
    • Administer RhoGAM for Rh-negative patients at 28 weeks; also with miscarriage or abortion to prevent Rh-negative patients from developing antibodies, which may lead to stillbirth or anemia.

Amniotic Fluid Conditions

Polyhydramnios
  • Definition:
    • Amniotic fluid volume greater than 2000 mL.
    • Management Approach: Close monitoring; fluid removal; indomethacin can decrease fetal urine output.
    • Assessment Needs: Risk factors, larger than normal fundal height, abdominal discomfort, fetal heart rate (FHR) evaluation, and gastrointestinal malformations expected.
Oligohydramnios
  • Definition:
    • Amniotic fluid volume less than 500 mL.
    • Management Strategy: Serial monitoring; amnioinfusion and potential birth for fetal compromise. Assessment: Ensure fetal well-being remains reactive.

Hypertensive States in Pregnancy

  • Overview:
    • Affects peripheral vascular spasms, reducing blood vessel diameter and increasing blood pressure (BP) affecting kidney function.
  • Gestational Hypertension:
    • Occurs after the 20th week of gestation; no proteinuria.
    • BP levels: 140/90; treatment includes antihypertensives (e.g., Labetolol) and magnesium sulfate.
  • Pre-eclampsia (Mild/Severe):
    • Signs: Persistent headache, blurred vision, visual disturbances, protein in urine (1+/2+); BP at 140/90 or higher; mild edema.
  • Severe Eclampsia:
    • BP reaches 160/110, proteinuria (3+/4+), pitting edema, blurred vision, headaches, hyper-reflexia, epigastric pain, nausea, vomiting.
    • Complications: Include cerebral hemorrhage, circulatory collapse, heart failure, fetal hypoxia, and RUQ pain.
  • Eclampsia Events:
    • Onset marked by seizure activity; immediate precautions are crucial!
    • Management involves private rooms, minimized environmental stimuli, seizure prevention with IV magnesium sulfate, and fetal monitoring.
  • Monitoring Needs:
    • Watch for magnesium sulfate reactions (e.g., respiratory rate below 12, unreactive reflexes).
    • Administer Betamethasone if preterm.
    • If seizures occur: Administer Ativan; magnesium sulfate given at a rate of 4-6g/hour.

HELLP Syndrome

  • Description:
    • Hemolysis (breakdown of red blood cells), Elevated Liver enzymes, Low platelets; leads to several symptoms including headaches, bleeding (nose/mouth), petechiae, confusion, and hypotension.

Diabetes During Pregnancy

Pre-Gestational Diabetes
  • Symptoms by Trimester:
    • Early Pregnancy: Decreased insulin needs due to increased insulin production.
    • Post-First Trimester: Increased insulin needs due to placental hormones blocking insulin.
    • Post-Birth: Decreased insulin needs following loss of insulin-blocking hormones.
Gestational Diabetes
  • Associated Risks:
    • Increases chance of developing type II diabetes later; linked to obesity, age >25, and history of large babies (>10 lbs).
  • Screening Guidelines:
    • Low-risk patients screened at 28 weeks; high-risk patients at 25 weeks.
  • Signs and Symptoms:
    • Polyuria, polydipsia, polyphagia, fatigue, polyhydramnios.
  • Infant Complications:
    • Macrosomia (large baby), causing potential cephalopelvic disproportion and dystocia.
  • Management Strategies:
    • Dietary education: Limit carbs to 50% of daily calories, monitor fasting and post-meal blood glucose. Promote consistent exercise routines.

Signs of Fetal Compromise

  • Indicators:
    • Decreased fetal movement, non-reactive non-stress test (NST), poor biophysical profile (BPP).

Antepartum Testing

  • Ophthalmic Exams:
    • Assess optic nerve swelling or retinal detachment, especially in diabetic patients.
  • Glycosylated Hemoglobin (HbA1C):
    • Tests and monitors prediabetic clients and diabetes management.
  • Alpha-fetoprotein (AFP):
    • Low levels: Possible down syndrome;
    • High levels: Possible neural tube defects.
  • Non-stress test (NST):
    • Evaluates maternal contractions.

Postpartum Testing

  • Blood Glucose Testing:
    • Importance of continued monitoring for several weeks post-birth.

High-Risk Labor Management

Dystocia
  • Definition:
    • Long or difficult labor caused by:
    • Multiple gestation.
    • Maternal exhaustion.
    • Ineffective maternal pushing technique.
    • Fetal presentation issues (e.g., occiput posterior).
  • Management Techniques:
    • Promoting labor progress, providing physical and emotional support, empowerment strategies.
Pre-Term Labor
  • Definition:
    • Occurs <37 weeks gestation with regular contractions causing cervical effacement and dilation (≥1 cm).
  • Associated Factors:
    • Urinary tract infection (UTI), dehydration, chorioamnionitis (inflamed amniotic fluid).
  • Signs and Symptoms:
    • Persistent low backache, vaginal spotting, pelvic pressure, menstrual-like cramping, increasing vaginal discharge, frequent contractions.
  • Management Protocols:
    • No clear first-line tocolytic drugs; methods to prolong pregnancy typically range from 2 to 7 days for corticosteroid administration.
    • Corticosteroids (Betamethasone): Lower respiratory distress between 24-35 weeks gestation; magnesium sulfate can aid in delaying contractions pre-34 weeks.
    • IV Fluid Administration: Promote hydration, may also utilize tocolytics such as SQ Terbutaline or PO Indomethacin.
Assessment Needs for Pre-Term Labor
  • Normalization of Mucus Plug Loss: Late pregnancy.
  • Bloody Show Evaluations: Considered normal if present as labor progresses but must be evaluated if occurring preterm.
  • Precipitous Labor:
    • Definition: Completion of labor in <3 hours, lies risks of: premature separation of placental tissue, increased laceration risk, and potential development of amniotic fluid embolism, subdural hematoma in the infant.
Postterm Labor
  • Description:
    • Continues beyond 42 weeks' gestation.
  • Maternal Risks Include:
    • Risk of cesarean birth, dystocia (difficult labor), birth trauma postpartum hemorrhage, and infection.
  • Fetal Risks Include:
    • Macrosomia (large baby), shoulder dystocia (difficulty delivering shoulders), brachial plexus injuries, low Apgar scores, and cephalopelvic disproportion.
Uterine Rupture
  • Onset Noted By:
    • Sudden fetal bradycardia; may also present as a tearing pain.
  • Management:
    • Preparation for urgent cesarean delivery, vigilant maternal and fetal monitoring, and intravenous fluid administration.

Labor Induction and Augmentation

  • Induction:
    • Stimulating contractions through medical or surgical means.
  • Augmentation:
    • Enhancing ineffective contractions after labor has begun.
Labor Induction Therapeutic Management
  • Methods Include:
    • Use of herbal agents, castor oil, hot baths, enemas, sexual intercourse (with breast stimulation).
    • Medications:
    • Oxytocin administration; cervical ripening agents such as Dinoprostone (Cervidil), Cytotec.
    • Amniotomy: Rupturing membranes artificially by provider.
Bishop Score
  • Function:
    • Helps evaluate cervical readiness for induction or augmentation.
Contraindications for Induction or Augmentation
  • Previous classical incision, placenta previa, grand multiparity, over-distended uterus, active genital herpes, severe fetal distress, and fetal malposition (breech/transverse).

Amnioinfusion Indications

  • Use Cases:
    • Severe variable decelerations due to cord compression, oligohydramnios due to placental insufficiency, post-maturity, or ruptured membranes.

Cesarean Section Considerations

  • Risk Overview:
    • Higher risks to both mother and infant, longer recovery times, risk for preterm births.
  • Types of Uterine Incisions:
    • Transverse: Generally easier on the maternal body.
    • Classical (Vertical): Faster access during emergencies; however, carries risks for future pregnancies.
  • Post-Operative Interventions:
    • Fundal checks every 15 minutes, pain management, incision site inspections, assist with mobility, aiding in voiding, and preventing constipation.
  • Controversies in Vaginal Birth After Cesarean (VBAC):
    • Intricate relationships between uterine rupture and hemorrhage risks.
    • Contraindications include a previous classical incision, uterine surgery history, instances of placental abruption/rupture, twin/triplet pregnancies.

Shoulder Dystocia Management

  • Definition:
    • Anterior shoulder impacted above the pelvic brim, although anticipated in patients with:
    • Maternal diabetes,
    • History of macrosomia,
    • Maternal obesity, or large fetal size.
  • Observational Indicators:
    • Slow delivery of the infant's head, absence of spontaneous restitution, head recoiling against the perineum post-delivery.
  • Intervention Strategies:
    • McRoberts Maneuver: Pull knees toward the chest, apply suprapubic pressure, perform gentle traction on the head.

Appropriate Equipment Availability in Emergencies

  • Necessary resources may include:
    • Episiotomy instruments,
    • Urethral catheterization tools,
    • Infant resuscitation materials.

External Versions

  • Procedure:
    • A medical technique to change baby’s position from breech to vertex, follows prescribed provider protocols before 37 weeks.
    • Close monitoring via electronic fetal monitoring pre-and post-procedure to evaluate fetal well-being.

Intrauterine Fetal Demise/Miscarriages/Spontaneous Abortions

  • Common Occurrences: Most occur in the first trimester.
  • Assessment Indicators:
    • Vaginal spotting/bleeding often acts as the first sign, followed by lower abdominal pain.
    • Absence of fetal heart sounds can indicate termination; ultrasound is essential for confirmation.

Ectopic Pregnancies

  • Risk Factors Include:
    • Prior ectopic pregnancy,
    • Fallopian tube surgery,
    • Previous pelvic or abdominal surgery,
    • Certain STIs,
    • Pelvic inflammatory disease,
    • Endometriosis.
  • Treatment Protocols:
    • Methotrexate administration in 2 doses to stop cellular growth; pregnancy is absorbed by the body within 4-6 weeks.
    • Ensure hydration by consuming 2-3 liters of water daily to counteract kidney crystals.
  • Warning Signs:
    • Missed period, vaginal bleeding, unilateral lower abdominal pain, cramping, shoulder tip pain (due to bleeding).
  • Recuperation Plan:
    • Suggest waiting 3 months before attempting conception; Methotrexate for prior risks of birth defects.

Pre-Term Newborn Characteristics

  • Gestation Period: Less than 37 weeks.
  • Risk Factors: Infections, maternal or fetal distress, bleeding.
  • Newborn Characteristics:
  • Weight assessment and vitality, neurological status, skin condition, lanugo presence (indicative of maturity).

Post-Term Newborn Characteristics

  • Gestation Period: Beyond 42 weeks.
  • Management Needs:
    • Non-stress tests (NSTs), biophysical profile (BPP), and often labor induction.
  • Risks Associated: Meconium aspiration, hypoglycemia, temperature instability.
  • Physical Signs: Dry skin, creased soles, alertness, excessively long nails, common presence of meconium.

Meconium Aspiration Syndrome

  • Description: Occurs when baby inhales meconium at delivery, with particles leading to obesity in alveoli hindering oxygen intake.
  • Interventions Required:
    • Chest X-ray, selective suctioning, oxygen support, NICU admission for 10-14 days.

Infants Born to Hepatitis B Positive Mothers

  • Post-Exposure Prophylaxis:
    • Hep B immunoglobulin required within 12 hours of birth and Hep B vaccination to stimulate individual immune defense.

Hyperbilirubinemia

  • Defined As: Excess bilirubin in newborn blood, resulting from various conditions.
  • **Types:
    • Pathological Jaundice:** Within 24 hours postnatal; linked to blood incompatibilities.
    • Physiological Jaundice: After 24 hours natural processes; prevalent risk among breastfed infants.
  • Treatment Protocols:
    • Formula feeding enhancements if breastfeeding to encourage fluid expulsion and stooling.
  • Risk Range: Checking serum bilirubin levels for safety; above 10mg/dL is critical, with potential for bilirubin encephalopathy leading to kernicterus if untreated.
  • Therapeutic Actions:
    • Employ phototherapy for affected infants; cover eyes; administer IV immunoglobulin if needed.

Fetal Alcohol Syndrome

  • Definition: Range of physical, behavioral, and cognitive impairments due to prenatal alcohol exposure, with no cure for brain damage.
  • Assessment Indicators:
    • Poor sucking reflex at birth, low birth weights and small head sizes.

Neonatal Abstinence Syndrome

  • Definition: Newborns exposed to opioids, antidepressants, benzos, or barbiturates; characterized by tremors, seizures, overactive reflexes, poor feeding, excessive screaming, fever, perspiration, and respiratory distress (tachypnea).
  • Treatment Strategies: IV hydration, administration of IV morphine, swaddling practices, frequent feeding, and reducing stimuli in the environment to promote calmness.

Gastrointestinal Conditions

Gastroschisis
  • Definition: Birth defect creating an abdominal wall hole, allowing external exposure of intestines, liver, or stomach.
  • Treatment Interventions: TPN administration, covering with wet sterile dressing, preventing cold stress.
Omphalocele
  • Definition: Congenital defect with abdominal organs herniating through the umbilical cord enclosed by a thin membrane.
  • Surgical Management: Placement of silo for rebuilding of abdominal cavity; dressing needs for prevention of exposure risk.
Necrotizing Enterocolitis
  • Target Groups: Primarily preterm and formula-fed infants are at risk for GI illness due to intestinal trauma, inflammation, ischemia, or necrosis.
  • Signs of Distress: Abdominal distention, feeding intolerance, vomiting, bloody stools, lethargy, bradycardia/apnea episodes.
  • Key Interventions: Initiate NPO status, insert NG tube, administer IV hydration, and broad-spectrum antibiotics, while monitoring for perforation or septic conditions.

Spina B