KD

Key Concepts of Body Fluids and Electrolytes

Total Body Mass

  • Total body mass consists of solids and fluids.
    • Female: approximately 45% solids
    • Male: approximately 40% solids
  • Fluid composition:
    • Females: about 55% fluids
    • Males: around 50% fluids
    • Hypothesis for differences: Fat composition vs. muscle composition.

Breakdown of Body Fluids

  • Total body fluid is about 55% to 60% and includes water and dissolved solutes.
  • Breakdown of body fluids:
    • Intracellular Fluid (ICF):
    • Comprises 2/3 of total body fluid.
    • Found within cells.
    • Extracellular Fluid (ECF):
    • Comprises 1/3 of total body fluid.
    • Further divided into:
      • Interstitial Fluid: 80% of ECF, fluid between cells.
      • Blood Plasma: 20% of ECF, fluid component of blood.

Water Gain and Loss

  • Water gain is equal to water loss, approximately 2500 mL.
    • Sources of water gain:
    • Ingested liquids (water, coffee, soda).
    • Ingested foods (water content varies).
    • Metabolic water from cellular respiration.
  • Water loss occurs via:
    • Kidneys: largest contributor via urine.
    • Skin: through sweat.
    • Lungs: water loss during exhalation.
    • GI Tract: minimal loss, primarily during defecation.

Electrolyte Imbalances

  • Electrolytes are vital for maintaining fluid balance and homeostasis. Significant imbalances can disrupt bodily functions.

Sodium (Na)

  • Functions:
    • Muscle contraction
    • Nerve conduction
  • Imbalances:
    • Hyponatremia (low sodium):
    • Symptoms include mental confusion, muscle weakness, and headaches.
    • Hypernatremia (high sodium):
    • Symptoms may include intense thirst and hypertension.

Chloride (Cl)

  • Important as sodium chloride (NaCl), especially lost in sweat.
  • Imbalances lead to similar issues as sodium due to their relationship.

Potassium (K)

  • Involved in muscle contraction and regulating fluid volume.
  • Imbalances:
    • Hypokalemia (low potassium):
    • Symptoms include muscle fatigue and confusion.
    • Hyperkalemia (high potassium):
    • Symptoms can result in nausea and may lead to death through heart complications.

Calcium (Ca)

  • Key for nerve excitability, muscle response, and blood coagulation.
  • Imbalances:
    • Hypocalcemia (low calcium):
    • Symptoms include numbness, tetany, and convulsions.
    • Hypercalcemia (high calcium):
    • Symptoms can include lethargy and may lead to coma.

Additional Notes

  • Importance of electrolyte replenishment during physical activity; beverages like Gatorade help restore lost electrolytes and prevent conditions like hyponatremia.
  • Discussion on thirst center in brain related to maintaining fluid balance and body hydration.