Key Concepts of Body Fluids and Electrolytes
Total Body Mass
- Total body mass consists of solids and fluids.
- Female: approximately 45% solids
- Male: approximately 40% solids
- Fluid composition:
- Females: about 55% fluids
- Males: around 50% fluids
- Hypothesis for differences: Fat composition vs. muscle composition.
Breakdown of Body Fluids
- Total body fluid is about 55% to 60% and includes water and dissolved solutes.
- Breakdown of body fluids:
- Intracellular Fluid (ICF):
- Comprises 2/3 of total body fluid.
- Found within cells.
- Extracellular Fluid (ECF):
- Comprises 1/3 of total body fluid.
- Further divided into:
- Interstitial Fluid: 80% of ECF, fluid between cells.
- Blood Plasma: 20% of ECF, fluid component of blood.
Water Gain and Loss
- Water gain is equal to water loss, approximately 2500 mL.
- Sources of water gain:
- Ingested liquids (water, coffee, soda).
- Ingested foods (water content varies).
- Metabolic water from cellular respiration.
- Water loss occurs via:
- Kidneys: largest contributor via urine.
- Skin: through sweat.
- Lungs: water loss during exhalation.
- GI Tract: minimal loss, primarily during defecation.
Electrolyte Imbalances
- Electrolytes are vital for maintaining fluid balance and homeostasis. Significant imbalances can disrupt bodily functions.
Sodium (Na)
- Functions:
- Muscle contraction
- Nerve conduction
- Imbalances:
- Hyponatremia (low sodium):
- Symptoms include mental confusion, muscle weakness, and headaches.
- Hypernatremia (high sodium):
- Symptoms may include intense thirst and hypertension.
Chloride (Cl)
- Important as sodium chloride (NaCl), especially lost in sweat.
- Imbalances lead to similar issues as sodium due to their relationship.
Potassium (K)
- Involved in muscle contraction and regulating fluid volume.
- Imbalances:
- Hypokalemia (low potassium):
- Symptoms include muscle fatigue and confusion.
- Hyperkalemia (high potassium):
- Symptoms can result in nausea and may lead to death through heart complications.
Calcium (Ca)
- Key for nerve excitability, muscle response, and blood coagulation.
- Imbalances:
- Hypocalcemia (low calcium):
- Symptoms include numbness, tetany, and convulsions.
- Hypercalcemia (high calcium):
- Symptoms can include lethargy and may lead to coma.
Additional Notes
- Importance of electrolyte replenishment during physical activity; beverages like Gatorade help restore lost electrolytes and prevent conditions like hyponatremia.
- Discussion on thirst center in brain related to maintaining fluid balance and body hydration.