Week+3+Normal+Pregnancy+%26+Tests+Slides

Normal Pregnancy & Tests

  • Focus on physiological changes and developmental milestones during pregnancy.

Human Development

  • Key developmental periods: Pre-embryonic, Embryonic, and Fetal periods.

The Menstrual Cycle

  • Phases:

    • Follicular Phase: Day 1 to ~Day 14

    • Hormones: FSH, LH, Estrogen, Progesterone

    • Temperature: Basal body temperature at 36.4°C to 36.7°C

    • Luteal Phase: ~Day 14 to 28

    • Ovulation: Released ovum

Pre-embryonic Period

  • Duration: First two weeks post-conception.

    • Important processes:

    • Fertilization to implantation.

    • Best implantation site: Upper uterus due to rich vascular supply.

    • Thick uterine lining prevents deep attachment of the placenta.

Embryonic Period

  • Duration: 3rd to 8th week post-conception.

    • Major developments:

    • Completion of basic structures and organ systems.

    • Teratogens pose a significant risk for damage during this period.

    • Growth Patterns: Cephalocaudal (head-to-toe) and central-to-peripheral.

Fetal Period

  • Duration: 9 weeks post-conception until delivery.

    • Focus on:

    • Rapid cell division, organ refinement.

    • Vulnerability of the central nervous system throughout pregnancy.

Normal Fetal Growth

  • 12 weeks:

    • Length: 7-9 cm, Weight: 28 g.

  • 16 weeks:

    • Length: 10-17 cm, Weight: 55-120 g.

  • 20 weeks:

    • Length: 25 cm, Weight: 223 g.

  • 28 weeks:

    • Length: 35-38 cm, Weight: 1,200 g.

  • 32 weeks:

    • Length: 38-43 cm, Weight: 1,500-2,500 g.

  • 36 weeks:

    • Length: 42-49 cm, Weight: 1,900-2,700 g.

  • 40 weeks:

    • Length: 48-52 cm, Weight: 3,000 g.

Auxiliary Structures

  • Placenta:

Normal Pregnancy & Tests

  • Focus on physiological changes and developmental milestones during pregnancy.

  • Common Tests & Screenings:

    • First Trimester (Weeks 1-12):

    • Blood tests: Check blood type, Rh factor, anemia, infections (e.g., rubella, syphilis, hepatitis B, HIV).

    • Urine tests: Screen for UTIs, protein, glucose.

    • Ultrasound: Confirm pregnancy, estimate due date, check for multiple pregnancies, assess fetal heart rate and early development.

    • Nuchal Translucency (NT) scan: Assess risk for chromosomal abnormalities like Down syndrome.

    • Second Trimester (Weeks 13-28):

    • Ultrasound (Anomaly Scan/Level II): Detailed assessment of fetal anatomy, organ development, growth, and placental location (typically around weeks 18-22).

    • Maternal Serum Screening (Quad Screen): Blood test to assess risk for neural tube defects and chromosomal abnormalities.

    • Glucose Challenge Test (GCT): Screen for gestational diabetes (typically weeks 24-28).

    • Amniocentesis: Diagnostic procedure (if indicated) to detect chromosomal abnormalities or genetic conditions.

    • Third Trimester (Weeks 29-40):

    • Glucose Tolerance Test (GTT): Confirmatory test for gestational diabetes.

    • Group B Streptococcus (GBS) Screening: Swab test to detect GBS colonization (around weeks 35-37).

    • Cervical examination: Assess cervical dilation and effacement as pregnancy nears term.

    • Non-stress test (NST) or Biophysical Profile (BPP): Assess fetal well-being, movement, heart rate reactivity, and amniotic fluid volume (if concerns arise).

Human Development

  • Key developmental periods: Pre-embryonic, Embryonic, and Fetal periods.

The Menstrual Cycle

  • Phases:

    • Follicular Phase: Day 1 to ~Day 14

    • Hormones: FSH, LH, Estrogen, Progesterone

    • Temperature: Basal body temperature at 36.4∘C36.4^{\circ}C to 36.7∘C36.7^{\circ}C

    • Luteal Phase: ~Day 14 to 28

    • Ovulation: Released ovum

Pre-embryonic Period

  • Duration: First two weeks post-conception.

  • Important processes:

    • Fertilization to implantation.

    • Best implantation site: Upper uterus due to rich vascular supply.

    • Thick uterine lining prevents deep attachment of the placenta.

Embryonic Period

  • Duration: 3rd to 8th week post-conception.

  • Major developments:

    • Completion of basic structures and organ systems.

    • Teratogens pose a significant risk for damage during this period.

    • Growth Patterns: Cephalocaudal (head-to-toe) and central-to-peripheral.

Fetal Period

  • Duration: 9 weeks post-conception until delivery.

  • Focus on:

    • Rapid cell division, organ refinement.

    • Vulnerability of the central nervous system throughout pregnancy.

Normal Fetal Growth

  • 12 weeks:

    • Length: 7-9 cm, Weight: 28 g.

  • 16 weeks:

    • Length: 10-17 cm, Weight: 55-120 g.

  • 20 weeks:

    • Length: 25 cm, Weight: 223 g.

  • 28 weeks:

    • Length: 35-38 cm, Weight: 1,200 g.

  • 32 weeks:

    • Length: 38-43 cm, Weight: 1,500-2,500 g.

  • 36 weeks:

    • Length: 42-49 cm, Weight: 1,900-2,700 g.

  • 40 weeks:

    • Length: 48-52 cm, Weight: 3,000 g.

Auxiliary Structures

  • Placenta:

    • Function: Transfers nutrients and oxygen from the mother to the fetus, removes waste products from the fetus, and produces hormones (e.g., hCG, progesterone, estrogen) essential for maintaining pregnancy.

    • Structure: Develops from both maternal (decidua basalis) and fetal (chorion frondosum) tissues. It is a highly vascularized organ.

    • Barrier: Acts as a selective barrier, allowing beneficial substances to pass through while largely blocking harmful ones, though some drugs, alcohol, and viruses can cross.

    • Umbilical Cord: Connects the fetus to the placenta.

    • Contains two umbilical arteries (carrying deoxygenated blood and waste from fetus to placenta) and one umbilical vein (carrying oxygenated blood and nutrients from placenta to fetus).

    • Wharton's Jelly: Protective connective tissue surrounding the vessels within the cord, preventing compression.

  • Amniotic Sac (Amnion and Chorion): The fluid-filled sac that surrounds and protects the fetus.

    • Amniotic Fluid: Cushions the fetus, allows for fetal movement, helps maintain a constant temperature, and contributes to fetal lung and gastrointestinal development.

    • Volume increases throughout pregnancy, peaking around 34-36 weeks.

  • Yolk Sac: Present in early pregnancy; provides nourishment to the embryo before the placenta is fully functional and plays a role in the development of the circulatory system and germ cells.