Untitled Flashcard Set
Here are the core notes for your requested AP Biology topics, streamlined for quick review.
Unit 2: Cell Structure & Function
2.5 Membrane Transport:
Passive Transport: Movement of molecules from high to low concentration (down the gradient) without energy. Includes simple diffusion (small, nonpolar molecules) and facilitated diffusion (uses transport proteins for polar/charged molecules).
Active Transport: Requires ATP to move molecules against their concentration gradient (low to high).
Bulk Transport: Endocytosis (bringing matter in via vesicles) and Exocytosis (exporting waste or proteins).
2.7 Tonicity & Osmoregulation:
Hypertonic: Higher solute concentration outside; water leaves the cell (shriveling).
Hypotonic: Lower solute concentration outside; water enters the cell (swelling/bursting).
Isotonic: Equal concentration; no net water movement.
Unit 3: Cellular Energetics
3.2 Enzyme Catalysis:
Enzymes lower the activation energy required for a reaction.
Substrates bind to the active site (highly specific shape/charge).
Denaturation occurs when environmental changes (pH, temp) break bonds, changing the enzyme's shape and making it non-functional.
3.4 Cellular Energy:
Energy is coupled: Exergonic reactions (releasing energy) drive endergonic reactions (requiring energy).
Photosynthesis captures light to make sugars; Cellular Respiration breaks down sugars to produce ATP.
Unit 4: Cell Communication & Cell Cycle
4.3 Signal Transduction:
Reception: Ligand binds to a receptor (e.g., G-protein coupled receptors).
Transduction: The signal is amplified via a "cascade" of relay molecules (like cyclic AMP or kinases).
Response: The cell performs a specific task, such as turning on a gene or activating an enzyme.
4.4 Changes in Signal Transduction:
Any change in the shape of a receptor or relay protein (due to mutation or inhibitors) can block or over-activate the response, often leading to diseases like cancer or diabetes.
Unit 6: Gene Expression & Regulation
6.1 DNA & RNA Structure:
Nucleotides consist of a sugar, phosphate, and nitrogenous base.
DNA is antiparallel ($5' \rightarrow 3'$ and $3' \rightarrow 5'$) and uses deoxyribose.
6.3 Transcription & RNA Processing:
RNA polymerase synthesizes mRNA from a DNA template.
Processing (Eukaryotes only): Introns (non-coding) are removed, exons are joined. A 5' cap and poly-A tail are added for protection and export.
6.6 Gene Expression & Cell Specialization:
All cells in an organism have the same DNA. Specialization (e.g., a skin cell vs. a neuron) happens because different genes are "turned on" by specific transcription factors.
Unit 7: Natural Selection
7.2 Natural Selection:
Requires variation, overproduction of offspring, and differential survival.
Fitness is measured by reproductive success (how many offspring survive to reproduce).
7.5 Hardy-Weinberg Equilibrium:
A population is NOT evolving if it meets five conditions: No mutations, random mating, no natural selection, extremely large population, and no gene flow.
Equations: $p + q = 1$ (alleles) and $p^2 + 2pq + q^2 = 1$ (genotypes).
Unit 8: Ecology
8.2 Energy Flow:
Only about 10% of energy is transferred from one trophic level to the next; the rest is lost as heat.
8.5 Community Ecology:
Interactions include Competition (-/-), Predation/Herbivory (+/-), and Symbiosis (Mutualism +/+, Commensalism +/0, Parasitism +/-).
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Unit 3: Cellular Energetics
3.1 Overview of Metabolism:
Metabolism comprises all chemical reactions in an organism that maintain life, including catabolic (breaking down molecules for energy) and anabolic (building larger molecules from smaller ones) pathways.
3.2 Enzyme Catalysis:
Enzymes lower the activation energy required for a reaction.
Substrates bind to the active site (highly specific shape/charge).
Denaturation occurs when environmental changes (pH, temperature) break bonds, changing the enzyme's shape and making it non-functional.
3.3 Regulation of Enzymes:
Enzyme activity can be regulated via competitive and non-competitive inhibitors and allosteric sites.
Allosteric regulation can activate or inhibit enzyme activity through feedback mechanisms.
3.4 Cellular Energy:
Energy is coupled: Exergonic reactions (release energy) drive endergonic reactions (require energy).
Photosynthesis captures light energy to synthesize sugars; Cellular Respiration breaks down sugars to produce ATP.
3.5 ATP: The Energy Currency:
ATP (Adenosine Triphosphate) is the primary energy carrier in cells, providing energy for cellular processes.
Unit 6: Gene Expression & Regulation
6.1 DNA & RNA Structure:
Nucleotides consist of a sugar, phosphate, and nitrogenous base.
DNA is antiparallel ( and ) and uses deoxyribose.
6.2 DNA Replication:
DNA replication is semiconservative; each strand serves as a template for a new strand.
6.3 Transcription & RNA Processing:
RNA polymerase synthesizes mRNA from a DNA template.
Processing (Eukaryotes only): Introns (non-coding) are removed; exons are joined. A 5' cap and poly-A tail are added for protection and export.
6.4 Translation:
Ribosomes read mRNA sequences to assemble amino acids into polypeptide chains; tRNA molecules bring specific amino acids to the ribosome.
6.5 Regulation of Gene Expression:
Gene expression can be regulated at transcriptional, post-transcriptional, translational, and post-translational levels.
6.6 Gene Expression & Cell Specialization:
All cells in an organism have the same DNA; specialization occurs because different genes are "turned on" by specific transcription factors.
Unit 7: Natural Selection
7.1 Evolutionary Principles:
Evolution explains the variety of life based on natural selection, genetic drift, mutations, and gene flow.
7.2 Natural Selection:
Requires variation, overproduction of offspring, and differential survival.
Fitness is measured by reproductive success (how many offspring survive to reproduce).
7.3 Adaptations:
Adaptations are traits that enhance an organism's ability to survive and reproduce in its environment.
7.4 Speciation:
Speciation can occur through mechanisms like allopatric (geographical isolation) and sympatric (reproductive isolation) speciation.
7.5 Hardy-Weinberg Equilibrium:
A population is NOT evolving if it meets five conditions: No mutations, random mating, no natural selection, extremely large population, and no gene flow.
Equations: (alleles) and (genotypes).