neuro

NERVOUS SYSTEM

Components of the Nervous System

  • Central Nervous System (CNS)

    • Composed of:

    • Brain

    • Spinal Cord

  • Peripheral Nervous System (PNS)

    • Composed of:

    • Nerves of the Autonomic Nervous System

The Brain and Nervous System

  • Major Components of the Brain

    • Cerebrum

    • Brain Stem

    • Midbrain

    • Pons

    • Medulla Oblongata

    • Diencephalon

    • Thalamus

    • Hypothalamus

    • Pituitary Gland

    • Cerebellum

    • Spinal Cord

Spinal Nerves and Their Functions

  • Cervical Nerves

    • C1-C3: Neck Muscles

    • C4: Diaphragm

    • C5: Deltoid (Shoulder)

    • C6: Wrist

    • C7: Triceps

    • C7-C8: Fingers

    • T1: Hand

  • Thoracic Nerves

    • T2-T12: Intercostals (Trunk), Abdominals

    • T11-L2: Ejaculation

  • Lumbar Nerves

    • L2: Hips

    • L3: Quadriceps

    • L4-L5: Foot

  • Sacral and Coccygeal Nerves

    • S2: Penile Erection

    • S2-S3: Bowel and Bladder

Peripheral Nervous System (PNS)

  • Divided into:

    • Autonomic Nervous System (ANS)

    • Sympathetic:

      • Stress Response

    • Parasympathetic:

      • Peaceful State

Neuro Assessment

  • Key Components of Neuro Assessment:

    • Health history

    • Vital Signs (V.S.)

    • Level of Consciousness (LOC)

    • Orientation

    • Pupils Exam

    • Motor Function Assessment

    • “What's UP?” evaluation

    • Cerebellar Function (Romberg test)

    • Coordination

    • Sensory Exam

    • Reflexes Examination

Glasgow Coma Scale (GCS)

  • Eye Opening:

    • Spontaneous: 4

    • To Sound: 3

    • To Pain: 2

    • Never: 1

  • Motor Response:

    • Obeys Commands: 6

    • Localizes Pain: 5

    • Normal Flexion (Withdrawal): 4

    • Abnormal Flexion: 3

    • Extension: 2

    • None: 1

  • Verbal Response:

    • Oriented: 5

    • Confused Conversation: 4

    • Inappropriate Words: 3

    • Incomprehensible Sounds: 2

    • None: 1

  • Highest Possible Score: 15

Diagnostics for Nervous System Disorders

  • Types of Diagnostics:

    • Lab Tests

    • Lumbar Puncture

    • X-Ray

    • CT Scan

    • MRI Scan

    • Angiogram

    • Myelogram

    • EEG (Electroencephalogram)

Risk Factors for Nervous System Disorders

  • Potential Risk Factors:

    • Trauma

    • Hemorrhage

    • Tumors

    • Infection

    • Toxicity

    • Metabolic Disorders

    • Hypoxic Conditions

    • Hypertension

    • Cerebral Artery Disease

    • Smoking

    • Aging

    • Chemical Exposure

Increased Intracranial Pressure (ICP)

  • Causes of Increased ICP:

    • Trauma

    • Hemorrhage

    • Tumor

    • Edema

    • Inflammation

  • Signs and Symptoms (S/S):

    • Altered LOC

    • Restlessness/Irritability

    • Headache

    • Vomiting

    • Posturing

    • Hemiparesis

    • Dilated Pupils

    • Seizures

    • Increased Temperature

    • Cushing's Triad (Hypertension, Bradycardia, Irregular Respirations)

  • Prevention of Increased ICP:

    • Head of Bed (HOB) elevated 30-45 degrees

    • Avoid hip flexion

    • Keep head neutral

    • Avoid straining or stress

    • Regulate temperature

    • Maintain fluid balance

    • Decrease overall stress and metabolic demand

Clinical Scenarios for Nursing Care

  • Romberg Sign:

    • Indicates significant sway when standing erect with feet together, arms at the side, and eyes closed.

  • ICP Monitoring:

    • Observe for increased temperature, decreased pulse, decreased respiration, and increased blood pressure.

  • Patient Positioning:

    • Avoid turning the head to one side; maintain head midline and elevated to 30-45 degrees.

  • Client Education for Recovery:

    • Educate clients to avoid activities such as blowing the nose or coughing vigorously to prevent elevations in ICP.

  • Emergency Signs Post-Concussion:

    • Watch for vomiting, difficulty speaking, and difficulty awakening to know when to return to ER.

Central Nervous System Disorders

Infections
  • Inflammation from Bacteria or Virus

  • Signs and Symptoms:

    • Fever/Chills

    • Irritability

    • Nuchal Rigidity

    • Headache

    • Photophobia

    • Encephalopathy

    • Seizures/Lethargy

Meningitis
  • Definition: Inflammation of the meninges surrounding the brain and spinal cord.

  • Types: Bacterial or Viral

  • Signs and Symptoms (S/S):

    • High fever

    • Nuchal rigidity

    • Photophobia

    • Encephalopathy

  • Diagnosis: Lumbar Puncture (LP) is key.

  • Treatment: Antibiotics for bacterial meningitis and symptom management.

Encephalitis
  • Definition: Inflammation of brain tissue, most commonly viral.

  • Signs and Symptoms (S/S):

    • Headache

    • Malaise

    • Nausea/Vomiting

    • Fever

    • Nuchal Rigidity

    • Ataxia

    • Photophobia

    • Confusion

    • Decreased LOC

  • Diagnosis: CT scan, MRI, LP

  • Treatment: Control symptoms effectively.

Headaches
  • Types of Headaches:

    • Migraine:

    • Symptoms include pain, nausea, and visual changes.

    • Tension:

    • Described as a band squeezing the head.

    • Cluster:

    • Pain in and around one eye.

  • Management of Headaches:

    • Use NSAIDs, antidepressants, or triptans for symptom control.

    • Identification and removal of aggravating factors.

Seizures
  • Definition: Can signal epilepsy or other neurologic disorders; characterized by abnormal electrical discharge.

  • Convulsions: Involuntary contractions of voluntary muscles.

  • Recovery Period: Varies; monitoring is essential.

  • Diagnostics: EEG is used to rule out underlying causes (CT).

  • Management: Use anticonvulsant medications, consider surgical options for control, and be prepared for emergency status epilepticus.

Seizure First Aid**:
  • Stay calm and with the patient; note the time.

  • Keep the patient safe, turn them on their side, and do not put anything in their mouth.

  • Do not restrain and loosen clothing until they are fully awake and alert.

Spinal Cord Injury (SCI)

  • Spinal Column Structure:

    • 7 Cervical Vertebrae

    • 12 Thoracic Vertebrae

    • 5 Lumbar Vertebrae

    • 5 Sacral Vertebrae

    • 4 Coccygeal (fused together)

  • Impacts of SCI:

    • C4: Quadriplegia/Tetraplegia (complete paralysis below the neck)

    • C6: Partial paralysis of hands and arms as well as lower body

    • T6: Paraplegia (paralysis below the chest)

    • L6: Paraplegia (paralysis below the waist)

Complications of SCI
  • Potential Complications:

    • Spinal Shock

    • Infection

    • Deep Vein Thrombosis (DVT)

    • Orthostatic Hypotension

    • Skin Breakdown

    • Urinary Tract Infection (UTI)

    • Depression

    • Autonomic Dysreflexia

  • Nursing Care Plan For SCI:

    • Impaired gas exchange

    • Ineffective airway clearance

    • Risk for autonomic dysreflexia

    • Alteration in bowel and bladder function

    • Impaired mobility

    • Self-care deficits

    • Impaired skin integrity

Neurodegenerative Disorders

Parkinson’s Disease
  • Definition: Destruction of cells leading to decreased dopamine production impacting semi-automatic movements.

  • Symptoms:

    • Primary:

    • Bradykinesia

    • Mask-like Expression

    • Soft Voice

    • Shuffling Gait

    • Difficulty Initiating Movements

    • Stooped Posture

    • Tremors in Hands

    • Secondary:

    • Generalized Weakness

    • Muscle Fatigue

    • Muscle Cramping

    • Diaphoresis

    • Constipation

    • Drooling

    • Orthostatic Hypotension

    • Slowed Mental Function

Huntington’s Disease
  • Characteristics: Progressive, hereditary, degenerative disorder affecting deep nuclei of the brain leading to loss of movement and intellect.

  • Symptoms:

    • Personality changes

    • Inappropriate behavior

    • Involuntary, irregular, jerky dance-like movements

    • Hesitant speech and eye blinking

    • Irregular trunk movements and constant motion

    • Wide gait

Alzheimer’s Disease
  • Definition: Most common type of dementia characterized by loss of mental functioning impacting memory, thinking, and daily activities.

  • Stages:

    • Stage 1: Lasts 2-4 years; increased forgetfulness.

    • Stage 2: Lasts 2-12 years; increased forgetfulness leads to irritability and inability to perform routine tasks, depression, sleep disruption, and hallucinations.

    • Stage 3: Progresses to complete dependency, loss of conversation ability, bowel/bladder control, and decreased mobility.

Peripheral Nervous System Disorders
Multiple Sclerosis (MS)
  • Definition: Chronic progressive degeneration affecting the myelin sheath around nerves.

  • Signs and Symptoms (S/S):

    • Numbness/tinkling (61.5%)

    • Cognitive Dysfunction (13.4%)

    • Depression (14.7%)

    • Dizziness (23.2%)

    • Vision Problems (40.2%)

    • Pain (19.3%)

    • Fatigue (40.1%)

    • Bladder Dysfunction (11.1%)

    • Muscle Spasms (17.2%)

    • Weakness (25.3%)

    • Walking Difficulty (48.9%)

  • Management: Lifestyle changes, symptom control, energy conservation, stress reduction, physical therapy, medications.

Myasthenia Gravis (MG)
  • Definition: An acquired autoimmune neuromuscular junction disorder causing antibodies to target skeletal muscle acetylcholine (Ach) receptors.

  • Symptoms:

    • Weakness and fatigue

    • Difficulty chewing and swallowing (Dysphagia)

    • Ptosis (drooping eyelids)

    • Diplopia (double vision)

    • Weak or hoarse voice

    • Difficulty breathing

  • Management:

    • Medications: Anticholinesterase drugs (Prostigmine, Mestinon)

    • Steroids and immunosuppressants

    • Plasmapheresis

Myasthenic and Cholinergic Crises
  • Myasthenic Crisis: Exacerbation of MG weakness leading to respiratory failure, commonly precipitated by respiratory infection.

  • Cholinergic Crisis: Caused by excess anticholinesterase leading to bradycardia, muscle twitches, muscle weakness, sweating, excessive secretions, and small pupils.

Amyotrophic Lateral Sclerosis (ALS)
  • Definition: A degenerative disease characterized by neuron degeneration and loss of the ability to initiate/control muscle movements.

  • Symptoms: Muscles weaken, atrophy, and twitch (fasciculations) as neurons die.

  • Management: Focus on diagnosis, management of symptoms, and slowing disease progression (e.g., Rilutek).

Guillain-Barré Syndrome
  • Definition: An acute inflammatory demyelinating polyneuropathy often following an infection leading to rapidly progressing flaccid paralysis.

  • Signs and Symptoms (S/S): Symmetrical ascending motor weakness; starts in the toes and ascends upward.

  • Management: May require oxygen/mechanical ventilation; immunoglobulin therapy/plasmapheresis, physiotherapy/occupational therapy for supportive care.

Cranial Nerve Disorders

Bell's Palsy
  • Symptoms: Loss of forehead and brow movements, inability to close eyes, drooping eyelids, loss of nasolabial folds, drooping of lower lip.

  • Management: Prevent complications with Prednisone, antivirals, analgesics, and heat/massage.

Trigeminal Neuralgia
  • Definition: A chronic pain condition affecting the trigeminal nerve.

  • Management: Medications to control pain, possibly surgical removal of irritant vessels, and additional treatments such as Botox/acupuncture.