Tubular Reabsorption and Diuretics

Tubular Reabsorption and Secretion

Differentiate between tubular reabsorption and secretion, paracellular and transcellular routes of solute/substance movement or transportation

Describe how and where sodium, water, organic compounds, and other substances (or ions) are reabsorbed in the nephron by both passive and active processes

Describe the location(s) in the nephron where tubular secretion occurs

Differentiate between obligatory and facultative water reabsorption and recall the locations in the nephron for these processes.

Describe how the aldosterone, antidiuretic hormone (ADH), and atrial

natriuretic peptide (ANP) each work together to regulate reabsorption and

secretion

Identify sites of actions of diuretics in the nephron.

diuretics

Define the term “diuretic” and describe the clinical uses of diuretics

Explain the mechanisms and sites of action of the 5 classes of diuretics

Discuss the primary side effects associated with diuretics

Explain how NSAIDs may reduce the effectiveness of some diuretics

quiz

  1. how does

  2. bicard is reabsorded from th renal tubules by NBEC1

  3. the following clinical conditons could be appropriately manged with specific diuretics except diarrhea

  4. based on its MOA which of the following drugs is CI in hyperkalemia? spironolactone

  5. which of the following diuretcs may induce hypokalemia? thiazide and furosemide

  6. faculate water absorption occurs in which of the following nephron sites? distal convulated tubule and collecting duct

  7. in the process of co-transporter/symport?

  8. MOA of thiazide diuretics NCC

  9. Correct about NSAIDS? reduce efficacy of some diuretics reduce the GFR

  10. How does furosemide cause hypokalemia?

  11. which of the following best explains the occurence of glycosura in indiviuals with DM? gluose concentration exceeds the transport maxium of renal rubules leading to glucose remaining in the filtrate

  12. When blood pH becomes too acidic, type A intercalated cells respond by secreting bicarb ions and retaining? false