CELL CYCLE
It is the series of events that a cell goes through as it grows and divides to produce two new daughter cells. It's a tightly regulated process that ensures proper duplication of cellular components and accurate division of genetic material.
Has 2 phases: Interphase & Mitosis
It is the distribution of DNA
Binary Fission happens in prokaryotic cells while Mitosis and Meiosis happens in eukaryotic cells
INTERPHASE
The cell spends most of their time in this phase
Has 3 sub-phases: G1, S, G2
GAP 1 (G1)
Cell growth
A checkpoint happens in order to check if the cell size is normal
SYNTHESIS (S)
DNA replication takes place, resulting in the duplication of chromosomes. Each chromosome now consists of two identical sister chromatids joined at the centromere
GAP 2 (G2)
The cell continues to grow and produces the necessary proteins and organelles for mitosis
A checkpoint occus in order for the cell to check if the DNA and chromosomes are copied before mitosis occurs.
MITOSIS
During mitosis, the cell undergoes a series of stages—prophase, metaphase, anaphase, and telophase—that ensure proper segregation of chromosomes to daughter cells. After telophase, the final stage is cytokinesis, where the cytoplasm divides, resulting in two genetically identical daughter cells.
Diploid
PROPHASE
Chromatin condenses to form chromosomes
Nucleolus disappears
Nuclear envelope breaks down
Mitotic spindle is formed
METAPHASE
Chromosomes / chromatids align at the metaphase plate at the center
A checkpoint occurs in order to check if the daughter cells have correct number in chromatids, nuclei, and spindle fibers.
ANAPHASE
Spindle fibers begin to shorten
Sister chromatids separate from each other
Chromatids move to opposite poles
TELOPHASE
Nuclear membrane starts to form
Chromosomes are no longer visible and folds back into chromatin
CYTOKINESIS
Division of cytoplasm, making two new diploid 5cells
Completes the entire stage of cell cycle.
APOPTOSIS
programmed cell death
forms a bleb
uses aPhagocytosis which eats cells
TUMORS
Has two types: Benin and Malignant
Benin: clump of solid cells, clustered together
Malignant: breaks away
Cancel can usually treated by the following:
Chemotherapy
Immunotheraphy
Surgery
Radiation
MEIOSIS
Sexual reproduction
2 divisions, 4 daughter cells
Known as reduction division as the chromosomes are halves
Non-identical Cells
Haploid
Meiosis I and Meiosis II
GAMETOGENESIS
Formation of sex cells, wherein spermatogensis is for males while oogenesis for female.
MEIOSIS I
Homologous chromosomes (chromosome pairs, with one inherited from each parent, that carry the same genes in the same order) are divided
2 haploid cells with duplicated chromosomes
PROPHASE I
Forms tetrads when chromosomes condenses
Nucleolus disappears
Nuclear envelope breaks down
Spindle fibers is formed
METAPHASE I
Homologous chromosomes align at the metaphase plate at the center
The chromosomes get mixed
ANAPHASE I
Homologous chromosomes separate from each other
TELOPHASE I
Nuclear membrane starts to form
Chromosomes are pulled in opposite sides
2 haploid cells
Spindle fibers disassemble
Cytokinesis occurs after
MEIOSIS II
Division of sister chromatids
PROPHASE II
New spindle forms
Chromosomes pulled at opposite sides
METAPHASE II
Line up along the spindle fiber
ANAPHASE II
Sister chromatids seperate
TELOPHASE II
Nuclear membrane starts to form
4 haploid cells
Spindle fibers disassemble
Cytokinesis occurs after
GENETIC DISORDERS CAUSE BY MEIOSIS
Chromosomes usually have 23 diploid pairs and 46 chromosomes in total. There are 22 pairs of autosomes (body cells) and 1 pair of sex chromosomes wherein XX are female chromosomes while XY are male chromosomes. The X is larger while the Y is shorter.
KARYOGRAM
Chromosomes are group together in pairs arranged by size (karyotyping)
NONDISJUNCTION
Failure to seperate of the chromosomes
TURNER’S SYNDROME
Sex chromosomes are missing one
DOWN SYNDROME
3 chromosomes in pair 21
KINEFELTER SYNDROME
More than 2 chromosomes in pair 23
XXXY, XXY, so on and so forth
JACOB SYNDROME (CRIMINAL SYNDROME/SUPERMALE SYNDROME)
Male extra Y chromosome
TRIPLE X SYNDROME (SUPERFEMALE SYNDROME)
Trisomy X (XXX)
Happens to female
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