upper motor system

Motor Systems

Upper Motor Neuron Control

  • Focus on the brainstem and spinal cord.

Movements vs. Acts

  • Movements: Simple reflexes characterized by brief muscle activation, including examples like:   - Eyeblink   - Hiccup   - Finger twitch

  • Acts: More complex, sequential movements, such as:   - Honking your car horn   - Writing your name   - Playing lead guitar

  • Motor Plan/Motor Program: A predefined set of muscle commands established before the action occurs.   - Important Note: Most of the brain's activities are motoric in nature, involving:     - Preparation to move     - Execution of movement     - Corrections to movements as needed.

Overview of Motor Systems

  • Descending Pathways: Classified into motor and descending (efferent) pathways, visually represented in red in diagrams.   - Pyramidal Tracts:     - Lateral corticospinal tract     - Anterior corticospinal tract   - Extrapyramidal tracts: Include:     - Rubrospinal tract
        - Reticulospinal tracts
        - Olivospinal tract
        - Vestibulospinal tract

  • Anatomical Regions:   - Sacral   - Lumbar   - Thoracic   - Cervical

  • Pyramidal Tract (PT): Initiates voluntary movements.

  • Extrapyramidal Tract (EPT): Involved in involuntary reflexes and movements.

Hierarchy of Motor Control Systems

  • Skeletal System and Muscles: Responsible for powering movement.

  • Spinal Cord: Controls skeletal muscles directly.

  • Brainstem: Integrates motor commands received from the cortex.

  • Primary Motor Cortex: Initiates commands for action.

  • Nonprimary Motor Cortex: Engages in cortical processing for more complex interactions.

  • Cerebellum and Basal Ganglia: Provide fine-tuning of motor commands and movements.

Forebrain Motor Systems Overview

  • Descending Systems:   - Upper Motor Neurons: Located in the Motor Cortex; responsible for planning, initiating, and directing voluntary movements.   - Brainstem Centers: Facilitate basic movements and manage postural control.   - Non-Motor Areas: Support overall coordination but do not initiate movement.   - Corticospinal Tract: Connects motor areas and lower motor neurons, integrating with the basal ganglia and spinal interneurons for movement coordination.   - Cerebellum: Involved in the timing, coordination, and precision of movements.

Overview of Descending Motor Control

  • Motor Pathways:   - Lateral White Matter: Involves:     - Axons from motor cortex facilitating skilled movement.     - Distal muscles involved in skilled movements.   - Medial White Matter: Involves:     - Axons from brainstem affecting posture and balance.     - Axial and proximal limb muscles.

  • Key Points About Muscle Control:   - Local circuit neurons in the intermediate zone of the spinal cord are arranged topographically, with:     - Medial controlling axial muscles.     - Lateral controlling distal limb muscles.

Pyramidal vs. Extrapyramidal

  • Pyramidal Systems:   - Components: Include the motor cortex, basal ganglia, cerebellum, thalamus, descending to brainstem and spinal cord.   - Functionality: Involved in the direct control of voluntary movements. Damage here results in muscle weakness, especially for limbs.

  • Extrapyramidal Systems:   - Components: Include brainstem paths (e.g., rubrospinal, reticulospinal) and spinal cord connections.   - Functionality: Involve involuntary control of reflexes and finer modulation of movement. Damage leads to movement control impairment.

Cerebral Cortex Nomenclature

  • Key Areas:   - Frontal Lobe
      - Parietal Lobe
      - Occipital Lobe
      - Temporal Lobe

  • Key Features:   - Central Sulcus: Divides the frontal and parietal lobes.   - Cingulate Gyrus and Sulcus: Median aspects of the frontal lobe, playing roles in emotion and cognition.

Upper Motor Neurons - Motor Cortices

  • Key Regions:   - Premotor Cortex and Supplementary Motor Cortex:     - Involved in planning and executing voluntary movements.     - Activity in these areas relates significantly to complex finger movement sequences.

  • Homunculus Representation:   - Derived from the work of Wilder Penfield during the 1930s, illustrates which parts of the motor cortex correspond to various body regions:     - Example of areas represented include shoulders, arms, legs, and head.

Functionality of Primary Motor Cortex

  • Layer 5 Neurons:   - Comprise upper motor neurons and include special types such as Betz cells responsible for fine motor control.

  • Corticospinal Pathway:   - Initiates voluntary movements connected primarily through the corticobulbar (upper face) and corticospinal tracts (limbs).

Pathways of Motor Control

  • Pyramidal Tract:   - Consists of axons from various motor areas, leading through structures like the internal capsule and cerebral peduncle, terminating in specific brainstem nuclei.

  • Corticobulbar and Corticospinal Projections:   - Control muscles of the face, head, neck (corticobulbar) and torso, limbs (corticospinal).

  • Decussation:   - Occurs primarily at the medullary pyramids, where 90% of fibers of the lateral corticospinal tract cross to the opposite side for control, while 10% of fibers remain in the ventral corticospinal tract.

Lesions and Consequences

  • Lower Motor Neuron Lesions:   - Cause total ipsilateral loss of facial expression due to damage to facial nuclei.

  • Leisoning Primary Motor Cortex:   - Results in contralateral loss but can see partial compensation due to collateral projections from the cingulate cortex.

Two Pathways of Motor Control and Crossings

  • Lateral Corticospinal Tract: 90% decussates at medullary pyramids.

  • Ventral Corticospinal Tract: 10% of fibers remain on the same side, controlling proximal limb muscles.

Functionality of Extrapyramidal System

  • Purpose:   - Controls involuntary reflexes and modulates overall movement for coordination.

  • Indirect Pathways Include:   - Colliculospinal, Reticulospinal, and Vestibulospinal tracts involved in posture, balance, and locomotion.

Motor Control in Brainstem

  • Brainstem Functions:   - Balance, posture, gaze fixation, and reflex controls affecting neck muscles.   - Influences axial and proximal limb muscles.

  • Pathways Include:   - Vestibulospinal for posture/balance and orienting movements, and reticulospinal for muscle control during postural adjustments.

Upper Motor Neuron Syndrome

  • Symptoms Include:   - Loss of cortical suppression of reflexes, presenting a Babinski sign indicating loss of descending control over reflex arcs.   - Normal findings in infants (developing reflex control).

Summary of Descending Motor Systems

  • Pyramidal Pathways: Facilitating voluntary movements via the corticospinal and corticobulbar tracts to motor neurons in the spinal cord or brainstem.

  • Extrapyramidal System: Governs involuntary reflexes and modulated movement tendencies, with pathways targeting spinal reflexes, locomotion, and posture control, integrated with CNS structures like the basal ganglia and cerebellum.