meds for 2 exam

Yes — this is a big med packet, so here’s the clean nursing-school version.

Respiratory / Gas Exchange Meds

Class

Meds listed

Mechanism

Common symptoms

Emergency symptoms

Black box

Antihistamines

Diphenhydramine

Blocks H1 histamine receptors → dries secretions

Drowsiness, dizziness, dry mouth, urinary retention, confusion in older adults

Severe confusion, hypotension, trouble urinating

None major listed

Decongestants

Pseudoephedrine, phenylephrine

Alpha stimulation → vasoconstriction → less nasal swelling

Restlessness, palpitations, ↑ BP

Severe hypertension, dysrhythmias

None major listed

Intranasal steroids

Beclomethasone, budesonide, flunisolide, fluticasone, mometasone, triamcinolone

Local anti-inflammatory effect in nose/airways

Headache, nasal irritation, sore throat, nosebleed, candidiasis

Severe infection, adrenal suppression with long-term/high dose

None major listed

Antitussives

Dextromethorphan, codeine, hydrocodone combos

Suppress cough center in medulla

Drowsiness, dizziness, nausea, constipation

Respiratory depression, serotonin syndrome, anaphylaxis

Opioid cough meds: addiction/abuse + respiratory depression risk

Expectorants

Guaifenesin

Thins mucus so patient can cough it out

Nausea, vomiting, GI upset

Rare allergy

None major listed

Beta₂ agonists

Albuterol, salmeterol

Bronchodilation by relaxing bronchial smooth muscle

Tachycardia, nervousness, tremor

Chest pain, dysrhythmias, paradoxical bronchospasm

LABA like salmeterol: increased asthma-related death risk if used alone without inhaled steroid.

Anticholinergic bronchodilators

Tiotropium

Blocks muscarinic receptors → bronchodilation

Dry mouth, headache, sinusitis, blurred vision

Worsening bronchospasm, urinary retention, narrow-angle glaucoma symptoms

None major listed

Methylxanthines

Theophylline

Relaxes bronchial smooth muscle; mild CNS/cardiac stimulant

Nausea, insomnia, tremor, tachycardia

Toxicity >20 mcg/mL, seizures, dysrhythmias

None major listed

Glucocorticoids

Prednisone, prednisolone, dexamethasone, methylprednisolone, inhaled fluticasone/beclomethasone

Decrease airway inflammation

Hoarseness, dry mouth, oral thrush; oral forms: mood changes, insomnia, hyperglycemia

Infection, GI bleed/ulcer, adrenal suppression, psychosis

None major listed

Mast cell stabilizer

Cromolyn

Prevents mast cells from releasing histamine

Throat irritation, cough, postnasal drip

Rebound bronchospasm, laryngeal edema

None major listed

Leukotriene modifiers

Montelukast, zafirlukast, zileuton

Blocks leukotrienes → less bronchoconstriction/inflammation

Headache, GI upset, ↑ liver enzymes

Suicidal thoughts, behavior/mood changes, liver injury

Montelukast: serious neuropsychiatric events including suicidal thoughts/behavior.

PDE inhibitors for COPD

Ensifentrine

↑ cAMP/cGMP → bronchodilation + ↓ inflammation

Anxiety, insomnia, diarrhea, back pain

Paradoxical bronchospasm, suicidal ideation, hypertension

None major listed

Respiratory meds and side effects are pulled from your respiratory chapter sections on antihistamines, intranasal steroids, dextromethorphan, bronchodilators, glucocorticoids, cromolyn, leukotriene antagonists, and tiotropium.


Diuretics

Class

Meds listed

Mechanism

Common symptoms

Emergency symptoms

Black box

Thiazides

Hydrochlorothiazide, chlorothiazide

clinical use-

this chic

c- chf

hypertension

insipidus

calcium calculi

Distal tubule: lose Na⁺, water, K⁺

MOST POTENT DIURETIC

Dizziness, headache, nausea, photosensitivity, polyuria

thinker hyper

glycemia

lipidemia

uricemia

calcemia

hypovalemia

hypotension

FIRST line in hypertension

monitor for hyperglycemia,

hypokalemia, hypotension

Hypokalemia, hyponatremia, renal failure, Stevens-Johnson syndrome

None major listed

Thiazide-like

Chlorthalidone, indapamide, metolazone

Similar to thiazides

Orthostatic hypotension, GI upset, low K⁺/Mg²⁺/Na⁺

Severe electrolyte imbalance, hypovolemia

None major listed

Loop diuretics

Furosemide, bumetanide, torsemide

MOST potent diuretic

think HE
HF

Hypertension

Edema

Loop of Henle: powerful loss of Na⁺, water, K⁺

Frequent urination, dizziness, dehydration, hypokalemia

think hypo

-atremia

-kalemia

-magneisum

-volemia

otoxyicity

hyperuricemia

Ototoxicity, severe dehydration, dysrhythmias from low K⁺

None major listed

Osmotic diuretic

Mannitol

Pulls water into renal tubule → diuresis

Fluid shifts, headache, nausea

Pulmonary edema, HF worsening, dehydration

None major listed

Carbonic anhydrase inhibitor

Acetazolamide

Blocks bicarbonate reabsorption

Tingling, metabolic acidosis, electrolyte loss

Severe acidosis, blood dyscrasias

None major listed

Potassium-sparing

Spironolactone, triamterene, amiloride

WEAK diuretic

should not be combined with other potassium supplements

Keeps K⁺ while removing Na⁺/water

Hyperkalemia, nausea, dizziness

Fatal dysrhythmias from high K⁺

None major listed

The chapter divides diuretics into thiazide/thiazide-like, loop, osmotic, carbonic anhydrase inhibitor, and potassium-sparing groups; hydrochlorothiazide specifically causes sodium/water/potassium loss and can cause serious hypokalemia and blood disorders.


Blood Pressure / Cardiac Meds

Class

Meds listed

Mechanism

Common symptoms

Emergency symptoms

Black box

ARBs

Valsartan, losartan, irbesartan, candesartan, eprosartan, olmesartan, azilsartan, telmisartan

Blocks angiotensin II receptor → vasodilation + ↓ aldosterone

Dizziness, headache, fatigue, GI upset

Angioedema, renal dysfunction, hyperkalemia

Avoid in pregnancy

Direct renin inhibitor

Aliskiren

Blocks renin → ↓ angiotensin I/II/aldosterone

Diarrhea, dizziness, hypotension

Angioedema, renal impairment, hyperkalemia

Avoid in pregnancy; avoid with ACE/ARB in diabetes

Calcium channel blockers

Amlodipine, verapamil, diltiazem, felodipine, isradipine, nicardipine, nifedipine, nisoldipine

Blocks calcium entry into heart/vessels → vasodilation

Flushing, dizziness, ankle edema, constipation, bradycardia

AV block, severe hypotension, dysrhythmias, angioedema

None major listed

Alpha blocker

Prazosin

Blocks alpha₁ receptors → vasodilation

Orthostatic hypotension, dizziness

Syncope/falls, severe hypotension

None major listed

Beta blocker

Atenolol

Blocks beta receptors → ↓ HR and BP

Fatigue, bradycardia, dizziness

Heart block, bronchospasm, rebound MI if stopped suddenly

Abrupt stopping can cause rebound ischemia/MI risk

Misc antihypertensive

Aprocitentan

Endothelin receptor antagonist → vasodilation

Edema, fluid retention, anemia, rash

Hepatotoxicity

Pregnancy/fetal toxicity concern

Your chapter specifically explains that ARBs block angiotensin II receptors, calcium channel blockers prevent calcium influx causing vasodilation, and amlodipine can cause edema, bradycardia, AV block, angioedema, dysrhythmia exacerbation, and thrombocytopenia.


Clotting / Antiplatelet / Thrombolytic Meds

Class

Meds listed

Mechanism

Common symptoms

Emergency symptoms

Black box

Antiplatelet

Clopidogrel

Blocks ADP platelet receptor → prevents platelet aggregation

Abdominal pain, dizziness, bruising, rash, diarrhea

GI/intracranial bleeding, TTP, pancytopenia, hepatic failure, Stevens-Johnson

CYP2C19 poor metabolizers: reduced effectiveness.

GP IIb/IIIa inhibitors

Abciximab, eptifibatide, tirofiban

Blocks fibrinogen binding to platelets

Bleeding, bruising

Major hemorrhage, thrombocytopenia

None major listed

Thrombolytics

Alteplase, tenecteplase, reteplase

Converts plasminogen → plasmin → breaks down clot

Bleeding, nausea, rash

Intracranial hemorrhage, stroke, anaphylaxis, dysrhythmias, pulmonary edema

Major bleeding/intracranial hemorrhage risk

Hemostatic

Aminocaproic acid

Stops fibrinolysis → helps control bleeding

Headache, dizziness, nausea, diarrhea

Thrombosis, bradycardia, hypotension

None major listed

Anticoagulant

Heparin

Activates antithrombin → prevents clot extension

Bleeding, bruising

HIT, hemorrhage

Major bleeding risk

Your clotting chapter lists clopidogrel as an antiplatelet that blocks ADP binding, GP IIb/IIIa inhibitors as platelet blockers, and thrombolytics like alteplase/tenecteplase/reteplase as clot-busters with hemorrhage as the major complication.


Cholesterol / Peripheral Blood Flow Meds

Class

Meds listed

Mechanism

Common symptoms

Emergency symptoms

Black box

Statins

GOLD STANDARD

Atorvastatin, lovastatin, pravastatin, simvastatin, rosuvastatin

MAY TAKE UP TO 2 WEEKS

(lifetime commitment)

nursing considerations-

  • give at night

  • monitor liver

  • annual eye exam

  • report msucle

  • aches and weakness

  • therapy is lifetime

Blocks HMG-CoA reductase → ↓ cholesterol production

works by inhibiting hmg, coa reductase, an anzyme in the liver used to produce chloesterol

GI upset, myalgia, weakness, headache

Rhabdomyolysis, hepatic/renal failure, stroke

None major listed

Bile acid sequestrants

Cholestyramine, colestipol

(usually powder form)

(works well with statins)

Bind bile acids in gut → body uses cholesterol to make more bile

works inside the intenseness by binding to bile acids, forcing the body to excrete them

Constipation, bloating, GI upset

Bowel obstruction rare

None major listed

Niacin

Nicotinic acid

Lowers VLDL/triglycerides; raises HDL

(needs a lot of it to work to get to their therapeutic range)

Flushing, itching, GI upset

Hepatotoxicity, severe hypotension/syncope

None major listed

FLUSHING ITCHING

Cholesterol absorption inhibitor

Ezetimibe

(can be combined with statins for the best effect)

Blocks small intestinal from cholesterol absorption

Headache, GI upset

Liver injury, severe muscle pain if with statin

None major listed

Fibric acid derivative

Gemfibrozil

↓ triglycerides, ↑ HDL

act in the liver to control lipid metaboilism

GI upset, gallstones

Bleeding with anticoagulants, rhabdomyolysis with statins

None major listed

Peripheral vasodilator / antiplatelet

Cilostazol

Vasodilates + inhibits platelet aggregation

Headache, diarrhea, palpitations, dizziness

Tachycardia, bleeding, hypotension

Contraindicated in heart failure.

Blood viscosity reducer

Pentoxifylline

Improves RBC flexibility + ↓ blood viscosity

Nausea, vomiting, dizziness

Tachycardia, hypotension, blurred vision overdose

None major listed

Your peripheral blood flow/cholesterol chapter lists statin adverse effects like myalgia and rhabdomyolysis, cilostazol for claudication, and pentoxifylline for improving microcirculation by decreasing blood viscosity.


What I’d memorize first

For exam mode, don’t memorize every tiny side effect. Memorize the danger patterns:

Class

Biggest danger

Antihistamines

Sedation + anticholinergic effects

Decongestants

↑ BP, palpitations

Beta₂ agonists

Tachycardia, tremor, dysrhythmias

Theophylline

Narrow therapeutic range, seizures/dysrhythmias

Steroids

Hyperglycemia, infection, osteoporosis, adrenal suppression

Diuretics

Electrolyte problems

Thiazides

Low K⁺, high glucose, high uric acid

Loops

Low K⁺, dehydration, ototoxicity

Potassium-sparing

High K⁺

ACE/ARB/renin drugs

Hyperkalemia, renal dysfunction, pregnancy danger

Calcium channel blockers

Edema, bradycardia, hypotension

Antiplatelets/anticoagulants/thrombolytics

Bleeding

Statins

Muscle pain → rhabdomyolysis

Cilostazol

Do not give in heart failure