meds for 2 exam
Yes — this is a big med packet, so here’s the clean nursing-school version.
Respiratory / Gas Exchange Meds
Class | Meds listed | Mechanism | Common symptoms | Emergency symptoms | Black box |
|---|---|---|---|---|---|
Antihistamines | Diphenhydramine | Blocks H1 histamine receptors → dries secretions | Drowsiness, dizziness, dry mouth, urinary retention, confusion in older adults | Severe confusion, hypotension, trouble urinating | None major listed |
Decongestants | Pseudoephedrine, phenylephrine | Alpha stimulation → vasoconstriction → less nasal swelling | Restlessness, palpitations, ↑ BP | Severe hypertension, dysrhythmias | None major listed |
Intranasal steroids | Beclomethasone, budesonide, flunisolide, fluticasone, mometasone, triamcinolone | Local anti-inflammatory effect in nose/airways | Headache, nasal irritation, sore throat, nosebleed, candidiasis | Severe infection, adrenal suppression with long-term/high dose | None major listed |
Antitussives | Dextromethorphan, codeine, hydrocodone combos | Suppress cough center in medulla | Drowsiness, dizziness, nausea, constipation | Respiratory depression, serotonin syndrome, anaphylaxis | Opioid cough meds: addiction/abuse + respiratory depression risk |
Expectorants | Guaifenesin | Thins mucus so patient can cough it out | Nausea, vomiting, GI upset | Rare allergy | None major listed |
Beta₂ agonists | Albuterol, salmeterol | Bronchodilation by relaxing bronchial smooth muscle | Tachycardia, nervousness, tremor | Chest pain, dysrhythmias, paradoxical bronchospasm | LABA like salmeterol: increased asthma-related death risk if used alone without inhaled steroid. |
Anticholinergic bronchodilators | Tiotropium | Blocks muscarinic receptors → bronchodilation | Dry mouth, headache, sinusitis, blurred vision | Worsening bronchospasm, urinary retention, narrow-angle glaucoma symptoms | None major listed |
Methylxanthines | Theophylline | Relaxes bronchial smooth muscle; mild CNS/cardiac stimulant | Nausea, insomnia, tremor, tachycardia | Toxicity >20 mcg/mL, seizures, dysrhythmias | None major listed |
Glucocorticoids | Prednisone, prednisolone, dexamethasone, methylprednisolone, inhaled fluticasone/beclomethasone | Decrease airway inflammation | Hoarseness, dry mouth, oral thrush; oral forms: mood changes, insomnia, hyperglycemia | Infection, GI bleed/ulcer, adrenal suppression, psychosis | None major listed |
Mast cell stabilizer | Cromolyn | Prevents mast cells from releasing histamine | Throat irritation, cough, postnasal drip | Rebound bronchospasm, laryngeal edema | None major listed |
Leukotriene modifiers | Montelukast, zafirlukast, zileuton | Blocks leukotrienes → less bronchoconstriction/inflammation | Headache, GI upset, ↑ liver enzymes | Suicidal thoughts, behavior/mood changes, liver injury | Montelukast: serious neuropsychiatric events including suicidal thoughts/behavior. |
PDE inhibitors for COPD | Ensifentrine | ↑ cAMP/cGMP → bronchodilation + ↓ inflammation | Anxiety, insomnia, diarrhea, back pain | Paradoxical bronchospasm, suicidal ideation, hypertension | None major listed |
Respiratory meds and side effects are pulled from your respiratory chapter sections on antihistamines, intranasal steroids, dextromethorphan, bronchodilators, glucocorticoids, cromolyn, leukotriene antagonists, and tiotropium.
Diuretics
Class | Meds listed | Mechanism | Common symptoms | Emergency symptoms | Black box |
|---|---|---|---|---|---|
Thiazides | Hydrochlorothiazide, chlorothiazide clinical use- this chic c- chf hypertension insipidus calcium calculi | Distal tubule: lose Na⁺, water, K⁺ MOST POTENT DIURETIC | Dizziness, headache, nausea, photosensitivity, polyuria thinker hyper glycemia lipidemia uricemia calcemia hypovalemia hypotension FIRST line in hypertension monitor for hyperglycemia, hypokalemia, hypotension | Hypokalemia, hyponatremia, renal failure, Stevens-Johnson syndrome | None major listed |
Thiazide-like | Chlorthalidone, indapamide, metolazone | Similar to thiazides | Orthostatic hypotension, GI upset, low K⁺/Mg²⁺/Na⁺ | Severe electrolyte imbalance, hypovolemia | None major listed |
Loop diuretics | Furosemide, bumetanide, torsemide MOST potent diuretic think HE Hypertension Edema | Loop of Henle: powerful loss of Na⁺, water, K⁺ | Frequent urination, dizziness, dehydration, hypokalemia think hypo -atremia -kalemia -magneisum -volemia otoxyicity hyperuricemia | Ototoxicity, severe dehydration, dysrhythmias from low K⁺ | None major listed |
Osmotic diuretic | Mannitol | Pulls water into renal tubule → diuresis | Fluid shifts, headache, nausea | Pulmonary edema, HF worsening, dehydration | None major listed |
Carbonic anhydrase inhibitor | Acetazolamide | Blocks bicarbonate reabsorption | Tingling, metabolic acidosis, electrolyte loss | Severe acidosis, blood dyscrasias | None major listed |
Potassium-sparing | Spironolactone, triamterene, amiloride WEAK diuretic should not be combined with other potassium supplements | Keeps K⁺ while removing Na⁺/water | Hyperkalemia, nausea, dizziness | Fatal dysrhythmias from high K⁺ | None major listed |
The chapter divides diuretics into thiazide/thiazide-like, loop, osmotic, carbonic anhydrase inhibitor, and potassium-sparing groups; hydrochlorothiazide specifically causes sodium/water/potassium loss and can cause serious hypokalemia and blood disorders.
Blood Pressure / Cardiac Meds
Class | Meds listed | Mechanism | Common symptoms | Emergency symptoms | Black box |
|---|---|---|---|---|---|
ARBs | Valsartan, losartan, irbesartan, candesartan, eprosartan, olmesartan, azilsartan, telmisartan | Blocks angiotensin II receptor → vasodilation + ↓ aldosterone | Dizziness, headache, fatigue, GI upset | Angioedema, renal dysfunction, hyperkalemia | Avoid in pregnancy |
Direct renin inhibitor | Aliskiren | Blocks renin → ↓ angiotensin I/II/aldosterone | Diarrhea, dizziness, hypotension | Angioedema, renal impairment, hyperkalemia | Avoid in pregnancy; avoid with ACE/ARB in diabetes |
Calcium channel blockers | Amlodipine, verapamil, diltiazem, felodipine, isradipine, nicardipine, nifedipine, nisoldipine | Blocks calcium entry into heart/vessels → vasodilation | Flushing, dizziness, ankle edema, constipation, bradycardia | AV block, severe hypotension, dysrhythmias, angioedema | None major listed |
Alpha blocker | Prazosin | Blocks alpha₁ receptors → vasodilation | Orthostatic hypotension, dizziness | Syncope/falls, severe hypotension | None major listed |
Beta blocker | Atenolol | Blocks beta receptors → ↓ HR and BP | Fatigue, bradycardia, dizziness | Heart block, bronchospasm, rebound MI if stopped suddenly | Abrupt stopping can cause rebound ischemia/MI risk |
Misc antihypertensive | Aprocitentan | Endothelin receptor antagonist → vasodilation | Edema, fluid retention, anemia, rash | Hepatotoxicity | Pregnancy/fetal toxicity concern |
Your chapter specifically explains that ARBs block angiotensin II receptors, calcium channel blockers prevent calcium influx causing vasodilation, and amlodipine can cause edema, bradycardia, AV block, angioedema, dysrhythmia exacerbation, and thrombocytopenia.
Clotting / Antiplatelet / Thrombolytic Meds
Class | Meds listed | Mechanism | Common symptoms | Emergency symptoms | Black box |
|---|---|---|---|---|---|
Antiplatelet | Clopidogrel | Blocks ADP platelet receptor → prevents platelet aggregation | Abdominal pain, dizziness, bruising, rash, diarrhea | GI/intracranial bleeding, TTP, pancytopenia, hepatic failure, Stevens-Johnson | CYP2C19 poor metabolizers: reduced effectiveness. |
GP IIb/IIIa inhibitors | Abciximab, eptifibatide, tirofiban | Blocks fibrinogen binding to platelets | Bleeding, bruising | Major hemorrhage, thrombocytopenia | None major listed |
Thrombolytics | Alteplase, tenecteplase, reteplase | Converts plasminogen → plasmin → breaks down clot | Bleeding, nausea, rash | Intracranial hemorrhage, stroke, anaphylaxis, dysrhythmias, pulmonary edema | Major bleeding/intracranial hemorrhage risk |
Hemostatic | Aminocaproic acid | Stops fibrinolysis → helps control bleeding | Headache, dizziness, nausea, diarrhea | Thrombosis, bradycardia, hypotension | None major listed |
Anticoagulant | Heparin | Activates antithrombin → prevents clot extension | Bleeding, bruising | HIT, hemorrhage | Major bleeding risk |
Your clotting chapter lists clopidogrel as an antiplatelet that blocks ADP binding, GP IIb/IIIa inhibitors as platelet blockers, and thrombolytics like alteplase/tenecteplase/reteplase as clot-busters with hemorrhage as the major complication.
Cholesterol / Peripheral Blood Flow Meds
Class | Meds listed | Mechanism | Common symptoms | Emergency symptoms | Black box |
|---|---|---|---|---|---|
Statins GOLD STANDARD | Atorvastatin, lovastatin, pravastatin, simvastatin, rosuvastatin MAY TAKE UP TO 2 WEEKS (lifetime commitment) nursing considerations-
| Blocks HMG-CoA reductase → ↓ cholesterol production works by inhibiting hmg, coa reductase, an anzyme in the liver used to produce chloesterol | GI upset, myalgia, weakness, headache | Rhabdomyolysis, hepatic/renal failure, stroke | None major listed |
Bile acid sequestrants | Cholestyramine, colestipol (usually powder form) (works well with statins) | Bind bile acids in gut → body uses cholesterol to make more bile works inside the intenseness by binding to bile acids, forcing the body to excrete them | Constipation, bloating, GI upset | Bowel obstruction rare | None major listed |
Niacin | Nicotinic acid | Lowers VLDL/triglycerides; raises HDL (needs a lot of it to work to get to their therapeutic range) | Flushing, itching, GI upset | Hepatotoxicity, severe hypotension/syncope | None major listed FLUSHING ITCHING |
Cholesterol absorption inhibitor | Ezetimibe (can be combined with statins for the best effect) | Blocks small intestinal from cholesterol absorption | Headache, GI upset | Liver injury, severe muscle pain if with statin | None major listed |
Fibric acid derivative | Gemfibrozil | ↓ triglycerides, ↑ HDL act in the liver to control lipid metaboilism | GI upset, gallstones | Bleeding with anticoagulants, rhabdomyolysis with statins | None major listed |
Peripheral vasodilator / antiplatelet | Cilostazol | Vasodilates + inhibits platelet aggregation | Headache, diarrhea, palpitations, dizziness | Tachycardia, bleeding, hypotension | Contraindicated in heart failure. |
Blood viscosity reducer | Pentoxifylline | Improves RBC flexibility + ↓ blood viscosity | Nausea, vomiting, dizziness | Tachycardia, hypotension, blurred vision overdose | None major listed |
Your peripheral blood flow/cholesterol chapter lists statin adverse effects like myalgia and rhabdomyolysis, cilostazol for claudication, and pentoxifylline for improving microcirculation by decreasing blood viscosity.
What I’d memorize first
For exam mode, don’t memorize every tiny side effect. Memorize the danger patterns:
Class | Biggest danger |
|---|---|
Antihistamines | Sedation + anticholinergic effects |
Decongestants | ↑ BP, palpitations |
Beta₂ agonists | Tachycardia, tremor, dysrhythmias |
Theophylline | Narrow therapeutic range, seizures/dysrhythmias |
Steroids | Hyperglycemia, infection, osteoporosis, adrenal suppression |
Diuretics | Electrolyte problems |
Thiazides | Low K⁺, high glucose, high uric acid |
Loops | Low K⁺, dehydration, ototoxicity |
Potassium-sparing | High K⁺ |
ACE/ARB/renin drugs | Hyperkalemia, renal dysfunction, pregnancy danger |
Calcium channel blockers | Edema, bradycardia, hypotension |
Antiplatelets/anticoagulants/thrombolytics | Bleeding |
Statins | Muscle pain → rhabdomyolysis |
Cilostazol | Do not give in heart failure |