DIABETES

Diabetes Mellitus Type 1 vs Type 2

Definitions and Overview
  • Diabetes Mellitus is a chronic metabolic disorder characterized by high blood sugar (hyperglycemia) due to defects in insulin secretion, insulin action, or both.
  • Type 1 Diabetes Mellitus (T1DM): An autoimmune condition where the immune system attacks insulin-producing beta cells in the pancreas. Usually diagnosed in children and young adults.
  • Type 2 Diabetes Mellitus (T2DM): A more common form of diabetes characterized by insulin resistance and relative insulin deficiency. Often associated with obesity and typically diagnosed in adulthood.
Similarities and Differences
  • Similarities:
    • Both types result in high blood glucose levels.
    • Require monitoring of blood glucose to manage health and prevent complications.
    • Both may lead to complications like neuropathy, nephropathy, and retinopathy if uncontrolled.
  • Differences:
    • Etiology:
    • T1DM: Autoimmune destruction of beta cells.
    • T2DM: Insulin resistance and progressive beta cell dysfunction.
    • Onset:
    • T1DM: Often abrupt onset, typically in childhood or adolescence.
    • T2DM: Gradual onset, often in adults over 45 years.
    • Treatment:
    • T1DM: Requires insulin for survival.
    • T2DM: May initially be managed with lifestyle changes; may also require insulin or oral medications.

Risk Factors

  • Type 1 Diabetes: Genetic predisposition, autoimmune disease.
  • Type 2 Diabetes: Obesity, sedentary lifestyle, family history, older age, high blood pressure, abnormal cholesterol levels, and history of gestational diabetes.

Nursing Implications

  • Understand the patient’s type of diabetes and individual needs.
  • Be prepared to administer medications and educate the patient about self-management.
  • Monitor for signs of hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar).

Patient Assessment and Monitoring

Key Assessments
  • Regular monitoring of blood glucose levels -- target levels as determined by healthcare providers.
  • Assess body weight, dietary habits, and physical activity levels.
  • Monitor for diabetes-related complications (e.g., foot exams for neuropathy).
Monitoring Recommendations
  • Blood glucose monitoring:
    • Frequency may depend on the type of diabetes and treatment regimen.
    • T1DM: Often multiple times daily.
    • T2DM: May vary based on control and treatment plans.
  • HbA1c testing: Recommended at least every 3-6 months.

Patient Teaching

Essential Information for Patients
  • Importance of daily self-monitoring of blood glucose and keeping records.
  • Understanding of how different factors can affect blood sugar levels:
    • Diet composition (carbohydrate intake)
    • Physical activity
    • Illness or stress
  • Administration of medication:
    • Specifics on how to take insulin and/or oral medications (e.g., Metformin).
    • Recognizing signs and symptoms of hypo- and hyperglycemia and appropriate actions to take.
Home Management
  • Patients should learn:
    • Monitoring techniques for blood glucose (e.g., use of glucometers).
    • Importance of medication adherence and methods of injections (insulin).
    • Meal planning and carbohydrate counting.
    • Emergency contacts and protocols for low blood sugar episodes.

Treatment and Medications for Diabetes Mellitus

Overview of Medications
  • Metformin: First-line oral medication for T2DM that helps lower blood sugar levels by improving insulin sensitivity and decreasing hepatic glucose production.
  • Insulin Therapy: Essential for T1DM and sometimes required for advanced T2DM.
Types of Insulin
  • Rapid-acting Insulin (e.g., Lispro, Aspart): Starts working within 15 minutes, peaks in 1-2 hours, lasts 3-5 hours.
  • Short-acting Insulin (e.g., Regular Insulin): Starts working within 30 minutes, peaks in 2-4 hours, lasts 5-8 hours.
  • Intermediate-acting Insulin (e.g., NPH): Starts in 1-2 hours, peaks in 4-12 hours, lasts 12-18 hours.
  • Long-acting Insulin (e.g., Glargine, Detemir): Starts in 1-2 hours, no pronounced peak, lasts up to 24 hours.
  • Ultralong-acting Insulin (e.g., Degludec): Lasts beyond 24 hours without significant peaks.
Administration of Insulin
  • Understanding how to draw up and mix different insulins (if applicable):
    • Clear before cloudy when mixing rapid/short-acting insulin with NPH.
    • Do not mix long-acting insulins with others.
  • Injection techniques, sites, and rotation to prevent lipodystrophy.