organic_chemistry

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  • Organic Chemistry

  • Prepared By: Ms. Taban Ahmed

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Definition of Organic Chemistry

  • The study of compounds present in living organisms.

  • All organic compounds contain carbon.

  • Organic chemistry is fundamentally the chemistry of carbon.

Natural Sources of Organic Compounds

  • Compounds derived from living things include:

    • Carbohydrates

    • Proteins

    • Fats

    • Vitamins

    • Antibiotics

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  • A variety of organic products obtained from living things.

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Sources of Organic Compounds

  • Crude oil or coal provides:

    • Alkanes, Alkenes, Alkynes

    • Aromatic hydrocarbons

  • Methods of extraction include:

    • Fractional distillation

    • Destructive distillation

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Historical Definition of Organic Chemistry (Pre-1800s)

  • Organic chemistry was defined based on compounds obtained from living organisms.

  • It was believed that organic compounds could only be synthesized in living organisms.

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Modern Definition of Organic Chemistry

  • Many organic compounds are now recognized to be synthesized from inorganic substances.

  • Current definition:

    • The study of carbon compounds, excluding CO, CO2, carbonates, hydrogen carbonates, carbides, and cyanides.

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Development of Organic Chemistry as a Science

  • Historical distinction:

    • Organic compounds: obtained from living organisms.

    • Inorganic compounds: obtained from non-living sources.

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Key Event in Organic Chemistry Development

  • In 1828, German chemist Wohler synthesized urea from ammonium cyanate.

  • Reaction:

    • Heat applied to ammonium cyanate produced urea, showcasing synthesis beyond living organisms.

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Redefining Organic Chemistry

  • It is the study of carbon compounds obtained from natural sources or synthesized in laboratories, excluding traditional inorganic categories.

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Properties of Carbon Atoms

  • Each carbon atom has four unpaired electrons.

  • Tends to form four strong covalent bonds.

  • Capable of forming chains, branched chains, and rings due to its catenation ability.

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Examples of Carbon Compounds

  • Methane (CH4)

  • Carbon dioxide (CO2)

  • DNA

  • Benzene

  • Ethanol

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Examples of Organic Compounds

  • Paper (Cellulose)

  • Nail Polish (Nitrocellulose, butyl acetate)

  • Candle (Wax, tallow)

  • Fabric (Nylon, rayon)

  • Soap (Fatty acid salt)

  • Gasoline (Mixed hydrocarbons)

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Examples of Inorganic Compounds

  • Salt

  • Diamond

  • Water

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Catenation of Carbon

  • High strength of carbon-carbon bonds (bond enthalpy of 356 kJ/mol) explains its ability to catenate.

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Classification of Organic Compounds

  • Hydrocarbons: simplest organic compounds consisting only of carbon and hydrogen.

    • Main groups:

      • Saturated hydrocarbons - single carbon-carbon bonds.

      • Unsaturated hydrocarbons - have double or triple carbon-carbon bonds.

      • Aromatic hydrocarbons - contain a benzene ring.

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Aromatic Hydrocarbons

  • Contain benzene rings with alternating single and double carbon-carbon bonds described by resonance formulas.

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Molecular Models of Hydrocarbons

  • Visual representations of the structures of different hydrocarbons.

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Alkanes

  • Acyclic, saturated hydrocarbons with general formula CnH2n+2.

  • Simplest alkane: Methane (CH4).

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Three-Dimensional Model of Methane

  • Methane has a tetrahedral structure with bond angles of 109.5 degrees.

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Structural Formulas for Alkanes

  • Methane - CH4

  • Ethane - C2H6

  • Propane - C3H8

  • Butane - C4H10

    • Illustrate the straight-chain (normal) alkanes.

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Condensed Structural Formulas

  • Often used in organic chemistry for clarity, omitting explicit hydrogen atoms:

  • Examples:

    • Methane: CH4

    • Ethane: CH3CH3

    • Propane: CH3CH2CH3

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Constitutional Isomerism and Branched-Chain Alkanes

  • Isobutane (2-methylpropane) structure as an example of a branched-chain alkane.

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Structure of Isobutane

  • Visual representation:

    • H H

    • CH3 - C - CH2 - CH3

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Isomerism in Alkanes

  • Isobutane (C4H10) is a constitutional isomer of normal butane, sharing the same molecular formula but differing structurally.

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Models of Isobutane and Butane

  • Visual perspectives of isobutane and butane.

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Cycloalkanes

  • Cycloalkanes are cyclic, saturated hydrocarbons with general formula CnH2n, with carbon atoms joined in a ring.

  • Example: Structure of cyclobutane.

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Sources and Uses of Alkanes and Cycloalkanes

  • Principal sources: Fossil fuels (mixtures of alkanes, cycloalkanes, aromatic hydrocarbons).

  • Alkanes as starting points for:

    • Plastics

    • Pharmaceuticals

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Alkenes and Alkynes

  • Alkenes and alkynes: unsaturated hydrocarbons with double or triple carbon-carbon bonds.

  • Hydrogenation can convert them to saturated compounds.

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Alkenes and Their Isomers

  • General formula for alkenes: CnH2n.

  • Simplest alkene: Ethylene.

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Geometric Isomers of Alkenes

  • Isomers where atoms occupy different relative positions in space.

  • Example: Cis-2-butene and trans-2-butene.

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Alkynes

  • Unsaturated hydrocarbons with carbon-carbon triple bonds.

  • General formula: CnH2n-2.

  • Simplest alkyne: Acetylene (ethyne).

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Aromatic Hydrocarbons

  • Characterized by six-membered benzene rings with alternating single and double bonds.

  • Example structures include benzene and toluene.

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Examples of Aromatic Hydrocarbons

  • Perfume

  • Vanilla extract

  • Cinnamon

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Combustion of Alkanes

  • All hydrocarbons burn in excess oxygen, producing carbon dioxide, water, and heat.

    • Example: Reaction in propane gas grill.

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Substitution Reactions of Alkanes

  • A substitution reaction involves an atom being replaced by another atom in a hydrocarbon.

    • Example: Reaction of ethane with Cl2.

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Ethane and Chlorination Reaction

  • Example Reaction:

    • H H

    • H - C - C - H + Cl2 → H - C - C - Cl + H-Cl

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Oxidation Reactions of Alkenes

  • Alkenes combust in oxygen;

  • Partial oxidation example with potassium permanganate results in color change (purple to brown).

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Addition Reactions of Alkenes

  • Alkenes are more reactive than alkanes due to double bond.

  • Example: Br2 addition to propene creates a saturated compound.

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Reaction Example for Addition of Halogens

  • CH3-CH=CH2 + Br2 → CH2Br-CHBr-CH3

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Naming Hydrocarbons

  • IUPAC naming rules for branched-chain alkanes:

    • Determine the longest chain.

    • Base name corresponds to number of carbon atoms.

    • Include branches in the full name.

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Steps for Naming

  1. Find the longest continuous carbon chain.

    • Example: CH3-CH2-CH2-CH3.

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Steps for Naming

  1. Name the branches as alkyl groups.

    • Reference Table of common alkyl groups.

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Steps for Naming

  1. Number the branches based on their position on the longest chain, starting from the closest end.

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Steps for Naming

  1. For multiple branches of the same type, use prefixes like di-, tri-, tetra-, with indicating locations.

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Reiteration of Naming Steps

  • Follow the structured approach for naming alkanes.

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Nomenclature of Alkenes and Alkynes

  • Naming follows similar rules as alkanes; endings change to –ene (alkenes) and –yne (alkynes).

  • Position of double/triple bonds indicated in names.

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Isomerism in Alkenes

  • Mention of cis and trans isomers in naming conventions.

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Derivatives of Hydrocarbons

  • Definition of functional group; reactive portions of molecules.

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Classification of Organic Compounds

  • Based on functional groups present in compounds.

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Example of Functional Groups

  • Comparison of propane and ethanol:

    • Propane: No reaction with sodium.

    • Ethanol: Reacts with sodium to produce hydrogen gas.

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Similarities Among Alcohols

  • Compounds exhibiting -OH functional group share similar properties and fall into the same homologous series.

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Homologous Series Definition

  • A series of compounds with the same functional group, differing by –CH2–.

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General Structure for Homologous Series

  • Examples identify members based on carbon atom count and structural formulas.

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Summary of First Four Straight-Chain Alkanes

  • Identification based on molecular formulas and IUPAC names:

    • Methane: CH4, Ethane: C2H6, Propane: C3H8, Butane: C4H10.

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Continuation of Structural Examples

  • Detailed structural formulae for the first four members of straight-chain alkanes.

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Features of Straight-Chain Alkanes

  • All members of a homologous series can be represented by a general formula highlighting trends in properties.

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Chemical Properties of Members

  • Similar chemical properties across members; gradual changes in physical properties relate to molecular mass.

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Data on Physical Properties

  • Table of the first 20 straight-chain alkanes:

    • Gas or liquid states; identified melting/boiling points.

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Physical Properties Continued

  • Properties for higher members of the alkane series, demonstrating trends.

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Functional Group Identification Example

  • Identify functional groups such as:

    • Carbon-carbon double bond, chlorino group in organic compounds.

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Additional Functional Groups

  • Identify amino (-NH2) and carboxyl (-COOH) groups in compounds.

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Homologous Series Identification Example

  • Classify compounds like esters and amides based on structure.

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Functional Group Classification

  • Examine series for amide and anhydride compounds.

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Analyzing Homologous Series

  • Examples provided for comparing compound classifications based on functional groups.

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Conclusion of Series Classification

  • Affirmative/Negative answers concluded for different pairs based on functional groups.

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  • Thank you!