Fungus and Protozoa organizer
Fungi
Aspergillus
Disease: Skin and respiratory infections
Mode of Transmission: Spores and contact
Special Notes: Opportunistic pathogen
Blastomyces
Disease: Respiratory issues
Mode of Transmission: Inhalation of spores
Special Notes: Opportunistic pathogen
Candida albicans
Disease: Yeast infections, thrush, skin infections
Mode of Transmission: Opportunistic; part of normal microbiota
Special Notes: Dimorphic; yeast form in the body, hyphal form at room temperature
Histoplasma capsulatum
Disease: Pneumonia
Mode of Transmission: Inhalation of spores from bat and bird droppings
Special Notes: Found in Ohio and Mississippi valley regions in moist soil
Pneumocystis jirovecii
Disease: PCP pneumonia or pneumocystis pneumonia
Mode of Transmission: Opportunistic infection
Special Notes: Difficult to treat; common in AIDS patients
Trichophyton
Disease: Athlete’s foot, jock itch, ringworm (Tineas)
Mode of Transmission: Direct contact
Protozoa
Acanthamoeba
Disease: Keratitis and meningitis
Mode of Transmission: Found in lake, river, and pond water; enters through the nose
Special Notes: Can reach the brain
Babesia
Disease: Asymptomatic to fatigue, malaise, fever, chills (malaria-like)
Mode of Transmission: Vector-borne by tick (reservoir in wild and domestic animals)
Special Notes: Diagnosed by blood smear (intracellular)
Balantidium coli
Disease: Diarrhea
Mode of Transmission: Contaminated water (swine/pig feces)
Special Notes: Opportunistic; mainly a concern in immunocompromised individuals
Cryptosporidium
Disease: Gastrointestinal issues, diarrhea
Mode of Transmission: Fecal-oral route via contaminated water (vehicle)
Special Notes: Diagnosed by stool samples microscopically
Entamoeba histolytica
Disease: Bloody diarrhea, amebic dysentery
Mode of Transmission: Contaminated water (fecal-oral route)
Giardia lambia
Disease: Diarrhea
Mode of Transmission: Contaminated water (fecal-oral route)
Special Notes: Exhibits antigenic variation
Leishmania
Disease: Cutaneous and visceral infections
Mode of Transmission: Vector-borne by sand fly
Special Notes: Not commonly seen in the US
Plasmodium
Disease: Malaria
Mode of Transmission: Mosquitos
Special Notes: Diagnosed by blood smear (intracellular)
Toxoplasma gondii
Disease: Toxoplasmosis
Mode of Transmission: Cat feces
Special Notes: Pregnant women need to take special care as it can cause miscarriage
Trichomonas vaginalis
Disease: Trichomoniasis
Mode of Transmission: Vaginal infections (STD, direct contact)
Special Notes: Can be part of normal microbiota
Trypanosoma brucei
Disease: African sleeping sickness (undulating fever, inability to sleep)
Mode of Transmission: Vectors (tsetse fly)
Special Notes: Diagnosed by blood smear (extracellular); exhibits antigenic variation
Trypanosoma cruzi
Disease: Chagas disease (asymptomatic to diarrhea, enlarged spleen, fever, headache)
Mode of Transmission: Vector is the “kissing bug”
Special Notes: Diagnosed by blood smear (extracellular); exhibits antigenic variation