Glycolysis

Glycolysis

1.  - Glucose is phosphorylated by ATP to form glucose-6-phosphate, and producing ADP.

2. - Glucose-6-phosphate is rearranged to form fructose-6-phosphate.

3.- Fructose-6-phosphate is phosphorylated by another ATP to form fructose-1,6-disphosphate, and producing ADP.

4. - Fructose-1,6-disphosphate is split into two three-carbon molecules: glyceraldehyde-3-phosphate (G3P) and dihydroxyacetone phosphate (DHAP). DHAP is quickly converted to G3P, resulting in two molecules of G3P.

5. - Each G3P molecule is oxidized, transferring electrons to NAD+ to form NADH, while an inorganic phosphate (Pi) from the cytoplasm attaches to G3P, creating 1,3-disphosphoglycerate.

6.- One phosphate group from 1,3-disphosphoglycerate is transferred to ADP, forming ATP and 3-phosphoglycerate.

7. - 3-phosphoglycerate is converted to 2-phosphoglycerate.

8-9.    - 2-phosphoglycerate loses water to form phosphoenolpyruvate (PEP), which contains a high-energy phosphate bond.

10. - The high-energy phosphate from PEP is transferred to ADP, producing another ATP and forming pyruvate.