Protein and Exercise
Protein and Exercise
Introduction
Protein serves an essential role in the body:
Forms the structural basis of muscle tissue.
Acts as a major component of most enzymes present in the muscle.
Can be utilized as a source of energy during exercise.
Review of Chemical Structure
Composition of proteins:
Contains Carbon (C), Hydrogen (H), Oxygen (O), and Nitrogen (N).
Combines into 20 different amino acids.
Structural components of amino acids:
3 parts:
Amino group (NH₂)
Acid group (COOH)
Different combinations of Carbon, Hydrogen, Oxygen, and sometimes, Sulfur.
Formation of peptide bonds:
When two amino acids link, they form a peptide bond.
Amino Acids
Total of 20 amino acids necessary for protein synthesis:
Essential Amino Acids (EAAs): 9 (must be obtained through diet).
Nonessential Amino Acids: 11 (can be synthesized by the body).
Food sources:
Most animal and plant foods contain amino acids.
The specific amounts of each amino acid vary by food source.
Types of Protein
Complete Proteins:
Contain all essential amino acids; primarily from animal products.
Incomplete Proteins:
Contain some but not all essential amino acids; primarily from plant sources.
Complementary Proteins:
Combination of plant foods that create a complete protein when consumed together (e.g., grains with legumes).
Protein Metabolism in the Human Body
Breakdown of proteins:
Proteins are broken down into polypeptides and then into individual amino acids in the stomach and small intestine.
Absorption of amino acids:
Amino acids are absorbed through the small intestine wall, entering the bloodstream, and transported to the liver via the portal vein.
Role of the liver:
Acts as a critical center for amino acid metabolism; continually synthesizes a balanced amino acid mixture to meet the body’s protein requirements.
Metabolic Fate of Proteins
Usage of amino acids by body cells:
Body cells obtain amino acids from the bloodstream to synthesize proteins specific to their needs (e.g., tissues, enzymes, hormones).
Storage limitation: Body cells cannot store excess amino acids.
Functions of Protein
Vital roles in regulating human metabolism:
Enzymes as catalysts in biochemical reactions.
Hormones regulating physiological processes.
Fluid balance and acid-base balance maintenance.
Blood clotting process regulation.
Immunity through the production of antibodies.
Serves as a carrier for nutrients in the bloodstream.
Forms of Protein in the Body
Notable forms of proteins include:
Insulin: A hormone regulating glucose levels.
Neurotransmitters (e.g., serotonin): Chemical messengers in the nervous system.
Hemoglobin: The oxygen-carrying protein in blood.
Oxidative enzymes in mitochondria: Involved in energy production.
Recommended Dietary Allowance (RDA) for Protein
Protein requirements vary throughout the life cycle:
Average Adult: 0.8 g/kg, updated to 1.2-1.6 g/kg according to new Dietary Guidelines for Americans (DGA).
Infants (0-0.5 years): 1.5 g/kg
Children (0.5-1 years): 1.1 g/kg
Children (1-3 years): 1.1 g/kg
Children (4-13 years): 0.95 g/kg
Adolescents (14-18 years): 0.85 g/kg
Adults (19+ years): 0.8 g/kg
Calculation of Protein Needs
Example calculation for protein intake based on body weight (70 kg):
One gram of protein = 4 calories.
Daily caloric intake can range from 3,500 to 4,000 calories.
Percent protein intake can be around 12% to 15%.
Calculation of grams of protein needed:
Grams of protein: 131-150 g or 105-120 g, depending on caloric intake.
Grams of protein per kg: 1.9-2.1 or 1.5-1.7 g.
Protein Restricted Diets
Types of vegetarian diets:
Vegetarian: Excludes meat, but includes other animal products.
Ovo-vegetarians: Includes eggs.
Lacto-vegetarians: Includes dairy.
Ovolacto-vegetarians: Includes both eggs and dairy products.
Semi-vegetarians: Excludes red meat but consumes fish and poultry.
Vegan: Excludes all animal products, deriving nutrients from plant-based foods.
Nutritional concerns:
Ensuring sufficient calories is crucial.
Major focus is on obtaining adequate types of protein.
Potential mineral deficiencies (iron, calcium, zinc) may occur, particularly in vegans.
Vegans may require supplementation for vitamin D if not adequately exposed to sunlight and may risk vitamin B12 deficiency.
Effects of a Vegetarian Diet on Physical Performance
Research findings:
No significant differences found in aerobic or anaerobic capacities of vegetarian and non-vegetarian individuals.
Important for vegetarian athletes (especially females) to ensure adequate intake of iron and calcium.
Role of Protein in Exercise
Contribution of protein to energy cost:
Accounts for less than 5% of total energy cost during activity.
In prolonged endurance exercise, may contribute up to 15% of the total energy cost.
Adequate carbohydrate (CHO) intake before and during exercise helps minimize protein utilization.
Protein Metabolism During and After Exercise
Protein breakdown: occurs during exercise.
Protein synthesis: post-exercise phase critical for recovery.
Recovery period:
Muscle protein synthesis (MPS) is elevated for up to 24 hours following exercise.
Factors Influencing Muscle Protein Synthesis (MPS)
Friends (positive factors):
Frequent consumption of amino acids.
Adequate caloric intake.
Post-workout fueling strategies.
Proper carbohydrate intake.
Enemies (negative factors):
Low-calorie diets.
Frequent alcohol consumption.
Infrequent doses of protein.
Improper training techniques.
Lack of adequate sleep.
Training Effects on Protein Needs
Different types of training stimulate protein metabolism:
Aerobic exercise promotes the synthesis of metabolic enzymes.
Resistance training enhances muscle protein synthesis.
Recovery nutrition: ensures proper recovery post-exercise; sleep is essential.
Endurance training: enhances the potential for increased branched-chain amino acids (BCAA) capacity, thereby allowing muscles to derive energy from protein more effectively.
Training can reduce the production or accumulation of ammonia, leading to decreased fatigue.
Protein Needs for Athletes
Recommended dietary allowance for athletes:
General RDA: 0.8 g/kg/day
For a 175 lbs athlete, approximately 64 grams/day.
Athletic requirement: 1.2-2.2 g/kg/day, generally aiming for 1.6-2.2 g/kg to maximize anabolism.
Translation for a 175 lbs athlete: 95-175 grams/day.
Important to consider meal frequency: aim for 0.4 g/kg/meal for a minimum of 4 meals per day.
Special conditions:
Injury may increase the need to nearly 2.5 g/kg.
Aging can heighten protein requirements to preserve lean body mass.
Timing: of protein intake is crucial for maximizing benefits.
Worksheet: Calculate Your Athlete's Needs
Protein Intake Goal: 1.2 – 2.2 grams per kg of body weight per day.
Example calculation:
Weight in lbs: # / 2.2 = kg
kg x 1.2 – 2.2 g/kg = grams protein per day
Guidelines for post-workout: Aim for around 30 grams of protein.
Portion sizes include:
4 ounces of protein resembles the size of a smartphone.
1 ounce of animal-based protein contains approximately 7 grams of protein.
3 ounces of grilled chicken breast = 21 grams.
1 cup of milk = 8 grams.
2 tablespoons of peanut butter = 7 grams.
½ cup cooked beans = 7 grams.
¼ cup almonds = 7 grams.
¼ cup cottage cheese = 7 grams.
1 ounce of hard cheese = 7 grams.
1 cup of plain Greek yogurt = 15 grams.
1 large egg = 7 grams.
1 cup of chocolate milk = 8 grams.
Timing of Protein Intake
Pre-Workout:
Provide amino acids for upcoming activity; adjust intake as activity approaches and consider digestion times.
Post-Workout:
Focus on recovery; optimal intake includes protein, carbs, fluids, electrolytes, and antioxidants.
Aim for 20-30 grams (may exceed in larger meals), with excess not significantly enhancing muscle protein synthesis (MPS) but may increase amino acid oxidation.
Timing guidelines: consume within 2 hours post-exercise for optimal absorption.
Consider the quality of protein source, as plant-based sources might need larger quantities to meet EAA requirements.
Timing of All Meals
Every meal contributes to overall intake.
Bedtime Protein:
Potential benefits of pre-sleep protein intake include increased strength, lean muscle gain, decreased muscle soreness, and improved recovery.
Recommended intake: 30-40 g of high-quality protein before bed; products may vary in effectiveness based on type (casein or whey + casein combo is common).
More studies needed for comparisons of dairy vs. plant-based protein options.
References
Trommelen, Jorn et al. (2018). Presleep dietary protein-derived amino acids are incorporated into myofibrillar protein during postexercise overnight recovery. Am J Physiol Endocrinol Metab. 314(5):E457-E467.
Protein Sources and Quality
Protein Quality: Must contain essential amino acids.
Complete vs. Incomplete Proteins:
Complete proteins include all essential amino acids; incomplete proteins do not.
Protein Rich Foods: Primary sources include meats, eggs, fish, legumes, dairy, and nuts.
Additional nutritional benefits from protein-rich foods:
Yogurt provides probiotics and calcium.
Eggs are rich in vitamins A/D, lipids, and minerals.
Specific amounts of leucine in protein sources:
3 oz cooked salmon/tuna/chicken breast = 2-2.5 g of leucine.
1 egg = 1.2 g of leucine.
Protein Supplements
Types of Supplementation:
Isolated sources that may enter the bloodstream faster.
The role of carbohydrates in recovery (important for glycogen synthesis).
Awareness of additives such as artificial sweeteners and sugar alcohols; always read labels.
Common types of protein supplements: dairy-based (whey + casein) and plant-based (options include pumpkin seed, pea, soy, and blends like rice + pea).
Cited research:
Burd, Nicholas et al. (2019). Protein-containing food is more than the sum of its constituent amino acids for post-exercise muscle anabolic potential. Sports Science Exchange. Vol. 29, No. 194, 1-5.