Ch 10
Overview of Muscle Tissue
- Three types of muscle tissue: skeletal, cardiac, smooth.
- Basic function: generate muscle tension.
- Additional functions: movement, posture, joint stability, heat generation, regulation of material flow through hollow organs.
Striated Muscle Tissue
Skeletal Muscle
- Long, multinucleated cells (fibers), voluntary control, attached to skeleton.
Cardiac Muscle
- Branched cells, 1-2 nuclei, involuntary control, intercalated discs for coordination.
Smooth Muscle Tissue
- Spindle-shaped, single nucleus, involuntary, found in hollow organs, connected via gap junctions.
Properties of Muscle Cells
- Contractility: ability to contract without requiring cell shortening.
- Excitability: responding to stimuli.
- Conductivity: conducting electrical changes across membranes.
- Extensibility: stretching capabilities.
- Elasticity: returning to original length post-stretch.
Muscle Cell Structure
Myocyte Terminology
- Sarcoplasm: cytoplasm of myocyte.
- Sarcolemma: plasma membrane of myocyte.
- Sarcoplasmic Reticulum (SR): modified ER around myofibrils.
Myofibrils
- Cylindrical organelles crucial for contraction, packed with specialized proteins.
Myofilaments
- Thick filaments: bundles of myosin.
- Thin filaments: include actin, tropomyosin, troponin.
- Elastic filaments: titin for stabilization.
Sarcomere Structure
- I band: thin filaments only.
- Z disc: anchors thin filaments.
- A band: zone of overlap, both thick and thin filaments.
- H zone & M line: structures for supporting thick filaments.
Skeletal Muscle Organization
- Muscle fibers = fascicles =