A&P I Laboratory #12: Spinal Cord and Nerves

Dr. Benitez BIOL 2010 - A&P I Laboratory Notes: Spinal Cord, Cranial Nerves, and Spinal Nerves

A. Spinal Cord Gross Anatomy

Familiarize yourself with the following key features of the spinal cord:

  1. Cervical Enlargement - A widening of the spinal cord located in the cervical region that supplies nerves to the upper limbs.

  2. Lumbar Enlargement - A similar widening in the lumbar region that serves the lower limbs.

  3. Conus Medullaris - The tapered end of the spinal cord, marking the termination of the spinal cord proper.

  4. Cauda Equina - A bundle of spinal nerves and spinal nerve rootlets extending from the conus medullaris, resembling a horse's tail.

  5. Filum Terminale - A slender extension of the pia mater that anchors the spinal cord to the coccyx, providing stability.

  6. Dura Mater - The tough outermost layer of the meninges that surrounds the brain and spinal cord.

  7. Denticulate Ligament - A small ligamentous structure that helps anchor the spinal cord laterally to the dura mater.

  8. Subdural Space - The potential space between the dura mater and the arachnoid mater, which can accumulate fluid or blood.

  9. Arachnoid Mater - The middle layer of the meninges, characterized by a web-like appearance.

  10. Subarachnoid Space - The area beneath the arachnoid mater containing cerebrospinal fluid (CSF), which cushions the spinal cord.

  11. Pia Mater - The innermost layer of the meninges, closely adhering to the surface of the spinal cord.

B. Transverse Sectional Anatomy of Spinal Cord

Acquire knowledge on the following features as observed in a cross-section of the spinal cord:

  1. Anterior Median Fissure - A deep groove along the anterior midline of the spinal cord, facilitating its segmentation.

  2. Posterior Median Sulcus - A groove along the posterior midline of the spinal cord, complementing the anterior fissure.

  3. White Matter - Comprised of myelinated axons that form ascending and descending pathways for signals traveling to and from the brain.

  4. Gray Matter - Containing neuronal cell bodies, dendrites, and unmyelinated axons; it presents an "H" or butterfly shape in cross-sections.

  5. Anterior Horns - Regions of gray matter containing somatic motor neurons that innervate skeletal muscles.

  6. Posterior Horns - Areas of gray matter that house sensory neurons receiving input from the periphery.

  7. Lateral Horns - Present in thoracic and upper lumbar regions, containing autonomic motor neurons.

  8. Central Canal - A narrow passageway in the center of the spinal cord filled with cerebrospinal fluid (CSF).

C. Spinal Nerves, Plexuses and Peripheral Nerves

Understand the following spinal nerve structures and their respective functions:

  1. Anterior Root - Contains motor fibers that carry signals from the spinal cord to skeletal muscles (motor).

  2. Posterior Root - Contains sensory fibers that bring information from peripheral sensory receptors to the spinal cord (sensory).

  3. Dorsal Root Ganglion - A cluster of sensory neurons located on the posterior root of the spinal nerve responsible for transmitting sensory information.

  4. Spinal Nerve - A mixed nerve formed from the merging of the anterior and posterior roots, responsible for both motor and sensory functions.

  5. Ramus Communicans - Connective branches between spinal nerves and autonomic ganglia, contributing to the autonomic nervous system.    

Cervical Plexus
  1. Phrenic Nerve - Major nerve arising from the cervical plexus that innervates the diaphragm, crucial for respiration.    

Brachial Plexus

Identify the following nerves within this plexus:

  1. Axillary Nerve - Innervates the deltoid and teres minor muscles, responsible for shoulder abduction.

  2. Musculocutaneous Nerve - Motor supply to the anterior compartment of the arm, sensory supply to the lateral forearm.

  3. Ulnar Nerve - Controls many hand muscles and provides sensation to the medial side of the hand.

  4. Median Nerve - Primarily innervates flexor muscles of the forearm and provides sensation to the lateral side of the hand.

  5. Radial Nerve - Responsible for the motor function of the posterior arm and forearm, impacting wrist extension.    

Lumbar Plexus
  1. Femoral Nerve - Major nerve arising from the lumbar plexus supplying the anterior thigh muscles involved in leg movement.    

Sacral Plexus
  1. Sciatic Nerve - The largest nerve in the body, innervating the hamstrings and the entire lower leg and foot.    

Structure of a Nerve

Familiarize yourself with the microscopic features of a nerve:

  1. Axons - The long projections of neurons that conduct impulses away from the neuron's cell body.

  2. Schwann Cells - Glial cells that wrap around axons in the peripheral nervous system, producing myelin sheaths for insulation.

  3. Fascicle - A bundle of axons grouped together, wrapped in connective tissue, forming a larger nerve.

  4. Endoneurium - The delicate connective tissue sheath surrounding each individual axon within the fascicle.

  5. Perineurium - A protective layer surrounding a fascicle of nerve fibers, providing additional support and containing blood vessels.

  6. Epineurium - The outermost layer of connective tissue that encloses the entire nerve, offering structural integrity.    

Cranial Nerves

Identify the following cranial nerves, along with their types (sensory, motor, or mixed) and primary functions:

  1. Olfactory Nerve (CN I) - Sensory; responsible for the sense of smell.

  2. Optic Nerve (CN II) - Sensory; responsible for vision.

  3. Oculomotor Nerve (CN III) - Motor; controls most of the eye's movements, including constriction of the pupil and maintaining an open eyelid.

  4. Trochlear Nerve (CN IV) - Motor; innervates the superior oblique muscle of the eye, allowing for downward and lateral movement.

  5. Trigeminal Nerve (CN V) - Mixed; responsible for sensation in the face and motor functions such as biting and chewing.

  6. Abducens Nerve (CN VI) - Motor; controls lateral eye movement by innervating the lateral rectus muscle.

  7. Facial Nerve (CN VII) - Mixed; responsible for facial expressions, and taste sensations from the anterior two-thirds of the tongue.

  8. Vestibulocochlear Nerve (CN VIII) - Sensory; responsible for hearing and balance.

  9. Glossopharyngeal Nerve (CN IX) - Mixed; involved in taste and swallowing, and contributes to the gag reflex.

  10. Vagus Nerve (CN X) - Mixed; serves various functions in the thorax and abdomen, including heart rate modulation and digestive tract control.

  11. Accessory Nerve (CN XI) - Motor; supplies muscles that allow for head movement, particularly the sternocleidomastoid and trapezius muscles.

  12. Hypoglossal Nerve (CN XII) - Motor; responsible for tongue movements involved in speech and swallowing.