Chemical Kinetics

  • Kinetics

    • the speed at which a chemical reaction occurs (Reaction rate)

    • also sheds light on reaction mechanism (exactly how the reaction occurs)

  • Factors that Affect Reaction Rates

    • 1. Physical state of the reactants

      • in order to react, molecules must come in contact with each other

      • the more homogenous (same structure) the mixture of reactants, the faster the molecules can react

      • the heterogenous reactions with solids proceed more rapidly if the surface area is increased

        • powder medicine—>stomach, enters blood quickly

        • tablet medicine—>slower

    • 2. Concentration of reactants

      • as the concentration of reactants increases, so does the likelihood that reactant molecules will collide

    • 3. Temperature

      • at higher temperatures, reactant molecules have more kinetic energy, move faster, and collide more often and with greater energy

        • ex: bacterial reaction (spoil milk) proceed rapidly at room temperature than at lower temperature (in the refrigerator)

    • 4. Presence of a catalyst

      • catalysts speed up reactions by changing the mechanism of the reaction (they affect the collisions)

      • catalysts are not consumed during the course of the reaction

  • Reaction Rates

    • rates of reactions can be determined by monitoring the change in concentration of either reactants or products as function of time (unit for reaction rate: M/s)

      • ex: hypothetical reaction A—>B

        • Average rate of appearance B= change in concentration of B/change in time = delta [B]/delta t

        • Average rate of disappearance of A = - change in concentration of A/change in time = - delta [A]/delta t

      • Sample exercise 14.1

  • Change of Rate with Time

    • rates decrease as reaction proceeds because the concentration of the reactants decrease.

      • as the reaction goes forward, there are fewer collisions between reactant molecules

  • Instantaneous Rate

    • the plot of [C4H9Cl] versus time for this reaction yields a curve like this

    • it shows how the concentration of the reactant changes with time which allows us to get the instantaneous rate of a reaction

    • the rate at particular instant during the reaction

    • the slope of a line tangent to the curve at any point is the instantaneous rate at that time

    • instantaneous rate = - 0.017M -0.042M / 800s - 400s = 6.3×10^-5 M/s

      • use the concentrations of the highest point of concentration subtracted from the lowest point of concentration

    • all reactions slow down over time

      • therefore, the best indicator of the rate of a reaction is the instantaneous rate near the beginning of the reaction (initial rate)

    • instantaneous rate at t=0 is called the initial rate

    • Sample exercise 14.2

  • Reaction Rates and Stoichiometry

    • in this reaction, the ratio of C4H9Cl to C4H9OH is 1:1

    • thus, the rate of disappearance of C4H9Cl is the same as the rate of appearance of C4H9OH

      • -delta[C4H9Cl]/delta t = [C4H9OH]/delta t

    • if the ratio is NOT 1:1…

      • ex: 2HI —> H2 + I2

        • rate = -1/2 (delta [HI] / delta t) = (delta [H2] / delta t) = (delta [I2] / delta t)

    • sample exercise 14.3

  • Concentration and Rate Laws

    • one can gain information about the rate of a reaction by seeing how the rate changes with changes in concentration

    • the equation is called rate law, and k is the rate constant

    • a A + b B —> c C + d D

      • [A]^a [B]^b —> [C]^c + [D]^d

        • the exponents tell the order of the reaction with respect to each reactant

    • since the rate law of the reaction…

      • rate = k[NH4+] [NO2^-]

        • the reaction is first order in [NH4+] and first order in [NO2^-]

  • Rate Constants

    • rate = k[NH4+][NO2^-]

      • k = rate/[NH4+][NO2]

    • larger value of k means fast reaction

  • Integrated Rate Laws

    • Rate = k[A] = d[A]/dt

    • rate laws can be converted into equations that show the relationship between concentration of the reactants and or products and time

    • calculus is used to integrate the rate law applied to: Overall order: 0, 1, and 2

      • for first order process…

        • ln[A]t - ln[A]0 = -kt or ln [A]t/[A]0 = -kt —> y = mx + b

          • [A]0 = initial concentration of A and [A]t is the concentration of A at some time, t, during the course of the reaction

          • Therefore, if a reaction is first-order, a plot of ln[A] vs. t will yield a straight line, and the slop of the line will be -k.

  • Second Order Reactions

    • Rate = k[A]²

    • 1/[A]t = it + 1/[A]0

      • also in the form of y = mx + b

    • So if a process is second order in A, a plot of t vs 1/[A] yields a straight line, and the slope of the line is k.

  • Zero Order Reactions

    • Rate of disappearance of reactant is independent of reaction concentration

  • Half Life

    • defined as time required for one-half of a reactant to react

    • Because [A] at t1/2 is one half of original [A], [A]t = 0.5 [A]0

    • For first order process, the half life does not depend on [A]0

    • Second order process half life depends on initial concentration

  • Temperature and Rate

    • as temperature increases, so does the reaction rate

    • k is temperature-dependent

  • Collision Model

    • in chemical reaction, bonds are broken and new bonds are formed

    • molecules can only react if they collide with eachother

  • Orientation Factor

    • In order for a reaction to occur, molecules must collide with the correct orientation and with enough energy to cause bond breakage and formation

  • Activation Energy

    • reactants need minimum amount of energy required for the product formation: Activation Energy (Ea)

    • just as a ball cannot get over a hill if it does not roll up the hill with enough energy, a reaction cannot occur unless the molecules possess sufficient energy to get over the activation energy barrier

  • Energy Profile Diagrams

    • it is helpful to visualize energy changes throughout a process on a energy profile [or] reaction coordinate diagram

    • the diagram shows the energy of the reactants and products (and therefore, delta E)

    • the high point on the diagram is the transition state

    • the species present at the transition state is called the activated complex

    • the energy gap between the reactants and the activated complex is the activation energy. Lower the Ea, faster the reaction

  • Effect Temperature

    • the fraction of molecules can be found through the expression f=e^-Ea/RT

      • the larger the fraction of molecules, reacts at a higher temperature

    • where R is the gas constant and T is the Kelvin temperature

  • Arrhenius Equation

    • a developed mathematical relationship between k and Ea

      • k = Ae^-Ea/RT

        • A=frequency factor, represents frequency of collision and probability of collisions with the proper orientation for reaction

  • Determination of Ea

    • taking the natural log Arrhenius equation

      • lnk = -Ea/RT + lnA

        • y = mx +b

    • therefore, if k is determined experimentally at several temperatures Ea can be calculated from the slope of a plot of ln k vs. 1/T

    • to find slope, m

      • m = delta y/delta x = (ln k2 - ln k1)/(1/T2 - 1/T1) or ln(k2/k1)/(1/T2 - 1/T1)

  • Ea is given by the plot of lnk against 1/T means that, higher the Ea, the stronger the temperature dependence of the rate constant (steeper the slope)

  • A high Ea signifies that the rate constant depends strongly on the temperature

  • If reaction has zero activation energy, its rate is independent of temperature

  • Reaction Mechanisms

    • sequence of events that describes the actual process by which reactants become products is called the reaction mechanism

    • reactions may occur all at once or through several discrete steps

    • each of these processes is known as an elementary reaction or elementary process

  • Molecularity

    • tells how many molecules are involved in the process

      • unimolecular; A—>products; Rate = k[A]

      • bimolecular; A+A—>products; Rate = [A]²

      • bimolecular; A+B—>products; Rate = [A][B]

      • termolecular; A+A+A—>products; Rate = [A]³

      • termolecular; A+A+B—>products; Rate = [A]²[B]

      • termolecular; A+B+C—>products; Rate = [A][B][C]

  • Multistep Mechanisms

    • consists of sequence of elementary reactions

    • ex: No2+CO—>NO+CO2

    • Experimentally, Rate = k[NO2]²

    • a proposed mechanism for this reaction is

      • step 1: NO2+NO2—>NO3+NO

      • step 2: NO3+CO—>NO2+CO2

    • The NO3 intermediate is consumed in the second step (product from step 1 used in step 2 = cancel out)

  • Rate-Determining Step

    • in a multistep process, one of the steps will be slower than all the others

    • the overall reaction cannot occur faster than this slowest, rate-determining step

    • NO2+CO—>NO+CO2

      • Experimentally, rate = k[NO2}²

      • a proposed mechanism for this reaction is

        • step 1: NO2+NO2—>NO3+NO (slow)

        • step 2: NO3+CO—>NO2+CO2 (fast)

      • rate constant for step 2 (k2) is much greater than step 1 rate constant k1. This observation supports the proposed mechanism

  • Fast initial step

    • 2NO+Br2—>2NOBr

    • the rate law for this reaction is found to be Rate = [NO]²[Br2]

    • because termolecular processes are rare, this rate law suggests a two-step mechanism

      • step 1: NO+Br2—>←-NOBr2 (fast)

      • step 2: NOBr2+NO—>2 NOBr (slow)

        • step 1 includes the forward and reverse reactions

        • the rate law for that step would be rate = k2[NOBr2][NO]

      • NOBr can react two ways::

        • With NO to form NOBr

        • by decomposition to reform NO and Br2

      • the reactants and products of the first step are in equilibrium with each other

        • therefore, Rate f = Rate r

        • k1[NO][Br2] = k-1[NOBr2]

        • solving for [NOBr2], gives us k1/k-1 [NO][Br2] = [NOBr2]

          • Rate = k2k1/k-1 [NO][Br2][NO] = k[NO]²[Br2] (overall rate)

  • Catalyst

    • increase the rate of reaction by decreasing the activation energy of the reaction

    • catalysts change the mechanism by which the process occurs

  • Homogenous Catalysis

  • Heterogenous Catalysis

    • one way a catalyst can speed up a reaction is by holding reactants together and helping bonds to break

  • Enzymes

    • are catalysts in biological systems

    • the substrate fits into the active site of the enzyme much like a key fits into a lock