PRACTICE
- Different types of pathogenic organisms are: viruses, bacteria, fungi, protozoa and other organisms that can cause infectious disease.
Endemic - expected levels of disease in a region
Epidemic - a rapid increase in cases higher than expected in a population within a region
SARS - it's an example of an epidemic
Pandemic - when an epidemic is widespread and crosses borders
Outbreak - is a small scale epidemic
A small scale epidemic is called an outbreak.
Virulence is an organisms ability to cause infectious disease
If some infectious agents are not very likely to cause disease we can say that they are not very virulent
An example of A disease that is not very virulent is polio
How are pathogens able to cause infection?
- They have flagella
- Pilai
- Capsules
- Endospores
- biofilms
- endotoxins
- Exotoxins
Flagella are protein filaments that help bacteria to move around
another name for fimbriae is pilli
pilai resemble a porcupine
a pathogen that binds to cells or grabs hold of them to infect them is Pillai
protective walls that surround some cell membranes of pathogens are capsules
A pathogen that makes macrophages and neutrophils is a capsule
a type of pathogen that is resistant to hot and cold and also resistant to drying and chemical agents are endospores
a bunker that is impermeable to our host antibody reaction is called biofilm
is it true or false that some pathogens use exotoxins and endotoxins to make themselves more virulent
proteins released by bacteria that cause disease manifestations are called exotoxins
A neurotoxin that acts on the nerves or motor end plates that can cause paralysis is an example of an exotoxin or an endotoxin
What type of toxin acts on the gastrointestinal tract to cause diarrhea. The answer is enterotoxin
Cytokines can cause rashes and fevers
the type of toxin that stimulates the release of cytokines is called pyrogenic exotoxin
endotoxins are found on gram negative bacteria
endotoxins are responsible for causing host defects
host defects are things like fever, changes in blood pressure, inflammation and lethal shock
once an agent infects a host the degree and severity of the infection will depend on the hosts ability to fight off the infectious agent
virulence and host susceptibility cannot be separated
The things that make a host susceptible to infection are
- Immune system
- Age
- Nutrition
- genetic defects
- Medication
- the ability of the host to prevent an infection from occurring is dependent on:
- Barriers
- Chemicals
- Immunity
at common effect of aging is that it weakens our specific and nonspecific defenses
Why are infants susceptible to infection and disease? Because their immune systems are not fully developed
Genetic defects happen because people may not have neutrophil that kill the bacteria
Chemicals in tears and saliva provide resistance to invading pathogens
some ways that host resistance can be compromised and make an individual susceptible to an infection are:
- if the skin or mucosa is breached
- cystic fibrosis patients who have poor ciliary function
- intubation and catheterization
- A patient with poor ciliary function may have cystic fibrosis.
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